N-acetyl Epithalon Amidate (50mg)
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99% PURITY GUARANTEE
99% PURITY GUARANTEE
Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.
Preparation & Handling Notice
The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.
RESEARCH USE ONLY
This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.
Strength: 50 mg
CAS: 307297-39-8
Chemical Formula: C₁₄H₂₂N₄O₉
Molecular weight: 446.45 g/mol
Peptide Sequence: Ala-Glu-Asp-Gly
Synonyms: Acetyl-Epithalon-Amidate, Ac-AEDG-NH₂, Epitalon modified
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
N acetyl Epithalon Amidate is a modified synthetic tetrapeptide based on Epithalon (Ala Glu Asp Gly). It is studied in cell aging, telomere regulation, and gene expression research models. The N acetyl and C terminal amidation changes may improve handling characteristics.
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Novera Research delivers high-quality research peptides developed under strict manufacturing and quality-control standards. Each product is carefully synthesized, tested, and handled to ensure consistency, reliability, and transparency for advanced research applications.
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- Stored and shipped under controlled conditions
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INFORMATION
What is N-acetyl Epithalon Amidate?
N-acetyl Epithalon Amidate is a synthetic tetrapeptide based on the Epithalon tetrapeptide motif (Ala‑Glu‑Asp‑Gly). This modified version includes N-acetylation and C-terminal amidation, which are commonly used to reduce susceptibility to exopeptidase degradation and to alter the peptide’s physicochemical properties. It is primarily studied in research on cell aging, gene expression, and telomere regulation.
This product is supplied strictly for laboratory research use only.
Product Specifications
- CAS Number: 307297-39-8
- Category: Peptides
- Subcategory: Longevity & Anti-Aging Peptides
- Sequence: Ala-Glu-Asp-Gly
- Chemical Formula: C₁₄H₂₂N₄O₉
- Molecular weight: 446.45 g/mol
- Purity: ≥98–99%
- Packaging Format: 50mg lyophilized powder in sterile research vial
- Storage Conditions: Store at -20°C, avoid light exposure
- Designation: For Laboratory Research Use Only
Key Characteristics of N-acetyl Epithalon Amidate
- High purity (≥98–99%), ideal for controlled experimental use.
- Short tetrapeptide structure studied in aging research models.
- End-capping modifications commonly used to reduce susceptibility to exopeptidase degradation and alter physicochemical properties.
- Supplied as lyophilized powder, providing flexibility for research preparation.
- Suitable for in vitro and preclinical laboratory investigations.
- Store at −20°C, protected from light and moisture.
- Not intended for diagnostic, therapeutic, or clinical use.
How N-acetyl Epithalon Amidate Supports Research
N-acetyl Epithalon Amidate is used in laboratory studies to explore cell aging, telomere biology, and gene-regulation pathways. Researchers examine its role in cell aging pathways and gene activity, including circadian-related gene regulation in experimental models.
It is often incorporated into experimental models to study cell lifespan markers and cellular molecular stability under controlled conditions.
Research Applications & Usage Information
N-acetyl Epithalon Amidate (50mg) is commonly used in laboratory research for:
- Investigating cell aging mechanisms.
- Research on telomere length regulation.
- Gene expression pathway studies.
- Experimental models of oxidative stress and cellular resilience.
- Molecular signaling pathway research.
- Aging and bioregulation studies in laboratory settings.
This peptide is not intended for human or veterinary use.
Handling and Storage Recommendations
- Store at −20°C immediately upon receipt.
- Protect from direct light exposure.
- Keep the vial tightly sealed when not in use.
- Minimize repeated freeze-thaw cycles.
- Allow the vial to reach room temperature before opening to prevent moisture condensation.
- Follow institutional laboratory safety guidelines during handling.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Khavinson V, Diomede F, Mironova E, et al. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules. 2020;25(3):609. Published 2020 Jan 30. doi:10.3390/molecules25030609
- Yue X, Liu SL, Guo JN, et al. Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. Aging (Albany NY). 2022;14(7):3191-3202. doi:10.18632/aging.204007
- Al-Dulaimi S, Thomas R, Matta S, Roberts T. Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology. 2025;26(5):178. Published 2025 Sep 4. doi:10.1007/s10522-025-10315-x
- Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł. Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties. Int J Mol Sci. 2025;26(6):2691. Published 2025 Mar 17. doi:10.3390/ijms26062691
What is N-acetyl Epithalon Amidate?
N-acetyl Epithalon Amidate is a synthetic tetrapeptide based on the Epithalon tetrapeptide motif (Ala‑Glu‑Asp‑Gly). This modified version includes N-acetylation and C-terminal amidation, which are commonly used to reduce susceptibility to exopeptidase degradation and to alter the peptide’s physicochemical properties. It is primarily studied in research on cell aging, gene expression, and telomere regulation.
This product is supplied strictly for laboratory research use only.
Product Specifications
- CAS Number: 307297-39-8
- Category: Peptides
- Subcategory: Longevity & Anti-Aging Peptides
- Sequence: Ala-Glu-Asp-Gly
- Chemical Formula: C₁₄H₂₂N₄O₉
- Molecular weight: 446.45 g/mol
- Purity: ≥98–99%
- Packaging Format: 50mg lyophilized powder in sterile research vial
- Storage Conditions: Store at -20°C, avoid light exposure
- Designation: For Laboratory Research Use Only
Key Characteristics of N-acetyl Epithalon Amidate
- High purity (≥98–99%), ideal for controlled experimental use.
- Short tetrapeptide structure studied in aging research models.
- End-capping modifications commonly used to reduce susceptibility to exopeptidase degradation and alter physicochemical properties.
- Supplied as lyophilized powder, providing flexibility for research preparation.
- Suitable for in vitro and preclinical laboratory investigations.
- Store at −20°C, protected from light and moisture.
- Not intended for diagnostic, therapeutic, or clinical use.
How N-acetyl Epithalon Amidate Supports Research
N-acetyl Epithalon Amidate is used in laboratory studies to explore cell aging, telomere biology, and gene-regulation pathways. Researchers examine its role in cell aging pathways and gene activity, including circadian-related gene regulation in experimental models.
It is often incorporated into experimental models to study cell lifespan markers and cellular molecular stability under controlled conditions.
Research Applications & Usage Information
N-acetyl Epithalon Amidate (50mg) is commonly used in laboratory research for:
- Investigating cell aging mechanisms.
- Research on telomere length regulation.
- Gene expression pathway studies.
- Experimental models of oxidative stress and cellular resilience.
- Molecular signaling pathway research.
- Aging and bioregulation studies in laboratory settings.
This peptide is not intended for human or veterinary use.
Handling and Storage Recommendations
- Store at −20°C immediately upon receipt.
- Protect from direct light exposure.
- Keep the vial tightly sealed when not in use.
- Minimize repeated freeze-thaw cycles.
- Allow the vial to reach room temperature before opening to prevent moisture condensation.
- Follow institutional laboratory safety guidelines during handling.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Khavinson V, Diomede F, Mironova E, et al. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules. 2020;25(3):609. Published 2020 Jan 30. doi:10.3390/molecules25030609
- Yue X, Liu SL, Guo JN, et al. Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. Aging (Albany NY). 2022;14(7):3191-3202. doi:10.18632/aging.204007
- Al-Dulaimi S, Thomas R, Matta S, Roberts T. Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology. 2025;26(5):178. Published 2025 Sep 4. doi:10.1007/s10522-025-10315-x
- Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł. Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties. Int J Mol Sci. 2025;26(6):2691. Published 2025 Mar 17. doi:10.3390/ijms26062691
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