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CIMZIA® is an injectable medication that effectively addresses inflammatory pain. Discover further details on purchasing CIMZIA®, its uses, potential side effects for patients, and more in the following sections.

What Is CIMZIA® Used For?

CIMZIA® is a Tumour Necrosis Factor Alpha (TNF-α) blocker. This injection is used to treat a variety of conditions:

Crohn’s Disease

Crohn’s disease is a condition which involves inflammation of some parts of the digestive system. CIMZIA® is introduced as a treatment option in the cases where the conventional treatments have failed.

Out of all the patients with Crohn’s disease who were treated with CIMZIA® at the clinical trial, 64% started experiencing improvement after six weeks. At 26 weeks, 48% of them reached the state of remission.

Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease that affects the synovial membrane that lines the joints. This causes painful swelling. In rare cases, rheumatoid arthritis causes inflammation in parts of the body other than joints, such as the eyes and lungs.

CIMZIA® injectable medications can help treat inflammation triggered by rheumatoid arthritis. Typically, patients experience pain relief 24 weeks after they start the treatment. Others may see benefits as quickly as after one to two weeks.

Plaque Psoriasis

Plaque psoriasis, the most common type of psoriasis, appears on the skin in the form of dry, flaky patches. For many patients, CIMZIA® has shown to be effective in relieving the symptoms of plaque psoriasis for nearly a year. They usually start seeing improvements after six weeks of treatment.

Psoriatic Arthritis

CIMZIA®’s clinical trial resulted in six out of ten patients experiencing improvement in symptoms of psoriatic arthritis, such as joint pain and swelling, after twelve weeks. Others saw improvement after one to two weeks. When it comes to skin-related symptoms, for the majority of the patients, the positive effects were visible after six months.

Ankylosing Spondylitis

Ankylosing spondylitis is a form of arthritis which is manifested as lower back pain. When treated with CIMZIA® dose, patients typically experience pain relief after twelve weeks, while some see improvements within the first week or two after this program.

Non-Radiographic Axial Spondyloarthritis

Swelling of the joints, back pain and stiffness are symptoms of non-radiographic axial spondyloarthritis that may take one year to improve in patients being treated with CIMZIA®. However, for some, it may only take two weeks.

How Does CIMZIA® Work?

CIMZIA®’s active ingredient is called certolizumab pegol. It is a type of antibody protein that has been designed to target a substance in your body called tumor necrosis factor (TNF) and acts as a TNF-α blocker. TNF-α is a cytokine whose role is to help control inflammation in the human body. It triggers inflammation in cases where there is a threat, such as a pathogen or tumour, in order to fend them off.

Excessive TNF-α levels may cause inflammatory or autoimmune conditions. Therefore, since CIMZIA® inhibits TNF-α, it works well for treating conditions induced by inflammation.

Cimzia (Certolizumab pegol) is administered via subcutaneous injection, typically in the front of the thigh or abdomen. The typical initial dose is 400 mg, given as two injections of 200 mg each at weeks 0, 2, and 4. Subsequently, the standard maintenance dose is 200 mg administered every other week. For certain individuals, the dosage may be adjusted to 400 mg every 4 weeks, except in cases of plaque psoriasis, where the usual maintenance dose is 200 mg every 2 weeks.

Side Effects

Some patients who undergo treatment with CIMZIA® injections may experience side effects. It is important for patients to talk to their doctor before taking Cimzia if they have certain conditions. During the CIMZIA®’s clinical trials, the most common adverse reactions included upper respiratory infections, rash, and urinary tract infections.

In some cases, patients may develop serious infections that can lead to hospitalization or death. Some of the more serious side effects include:

• Allergic reactions
• Heart failure
• Hepatitis B reactivation
•  Nervous system issues
• Immune reactions

Thus, it is of utmost importance that the injection be administered by a licensed healthcare provider, and if you are looking to buy CIMZIA® online, make sure that you make your purchases from trusted sources. The injection may also be administered by the patient or someone else, but that person needs to receive proper training from the medical professional.

CIMZIA® vs Competition

HUMIRA® is one of CIMZIA®’s biggest competitors. Both of these Tumour Necrosis Factor (TNF) blockers are created using living cells. The difference is that the active ingredient found in HUMIRA® is adalimumab, while CIMZIA® contains certolizumab pegol.

CIMZIA® and HUMIRA® are quite similar when it comes to their effects. They are both used to treat:

• Rheumatoid arthritis
• Crohn’s disease
• Psoriatic arthritis
•  Ankylosing spondylitis
• Plaque psoriasis

CIMZIA® is approved for treating non-radiographic axial spondyloarthritis, while HUMIRA® is not. On the other hand, HUMIRA® can be used to treat certain conditions in children, while CIMZIA® may not be safe for them.

Where Can I Buy CIMZIA®?

You can buy CIMZIA® at wholesale price from suppliers. You may contact our sales agents who can direct you where to buy this product. It is essential that you make sure you order CIMZIA® from authentic sources that are authorized to sell this product. Buying in bulk allows for cost savings and ensures a consistent supply at good price.