MONOVISC®

MONOVISC®

Manufacturer: Anika Therapeutics Active Substance(s): SODIUM…

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$349.00

What is MONOVISC?

Monovisc is an advanced orthopaedic product developed to relieve knee pain caused by osteoarthritis. This treatment contains cross-linked sodium hyaluronate, a high-molecular-weight form of hyaluronic acid derived through bacterial fermentation.

When injected into the knee joint, it supplements synovial fluid, improving lubrication and cushioning. By enhancing shock absorption, it reduces pain and promotes smoother mobility. Patients who do not respond adequately to oral drugs, physical therapy, or lifestyle changes may benefit from this injectable therapy.

The U.S. Food and Drug Administration (FDA) approved Monovisc knee injections in 2014, recognizing its safety and effectiveness in osteoarthritis management. Developed by Anika Therapeutics, a company specializing in regenerative medicine and joint health, Monovisc orthopaedic therapy reflects the manufacturer’s commitment to innovative treatments.

Since it is a prescription-only product, it must be sourced from verified distributors to ensure safety, authenticity, and compliance with medical standards.

Read our comprehensive article comparing Monovisc vs Orthovisc.

What Product Does This Brand Consist Of?

Monovisc is a single-use viscosupplement specifically formulated for the treatment of knee osteoarthritis. Its primary active ingredient, sodium hyaluronate, restores lost viscosity within the joint and improves function by mimicking the natural properties of healthy synovial fluid.

Unlike multi-dose regimens, this product is administered as a one-time injection, which simplifies therapy and increases patient compliance while delivering sustained pain relief.

The official Monovisc orthopaedic packaging includes a 4ml pre-filled syringe containing a 22mg/ml concentration of sodium hyaluronate. This design ensures ease of use and accurate dosing for healthcare providers performing knee injections.

The product is manufactured under strict quality standards by Anika Therapeutics, a leader in tissue healing and pain management innovations. By restoring natural cushioning in the joint, Monovisc helps patients achieve improved mobility and long-lasting comfort.

Product Details:

• Product Name: Monovisc
• Manufacturer: Anika Therapeutics
• Active Substance: Sodium Hyaluronate
• Strength: 22mg/ml
• Pack Size: 1 x 4ml pre-filled syringe

What Are the Benefits of MONOVISC Injection Treatment?

Monovisc provides significant benefits as a viscosupplementation treatment for patients with osteoarthritis of the knee. Developed by Anika Therapeutics, this product is administered as a single-dose knee injection, which sets it apart from multi-injection regimens.

The one-time application improves patient compliance, reduces the need for repeated visits, and simplifies the overall medical process. Because it is formulated using bacterial fermentation rather than avian sources, Monovisc is safe for patients who may be allergic to avian-derived drugs or proteins.

Key Benefits of Monovisc:

• Non-avian origin: Safe for patients with poultry, feather, or egg allergies
• Single-injection regimen: Convenient with no need for repeated knee injections
• Stabilized formula: Cross-linked hyaluronic acid ensures prolonged activity in the joint

In addition, the hyaluronic acid in Monovisc undergoes a controlled cross-linking process, making it more stable and effective. This design enhances its ability to restore synovial fluid within the joint, resulting in smoother mobility and longer-lasting pain relief.

Clinical research has shown that the effects can extend up to six months, offering a well-tolerated solution for patients who have not responded adequately to conventional meds such as oral analgesics or nonsteroidal anti-inflammatory drugs. These benefits position Monovisc as a reliable choice in both orthopedic and rheumatologic practice.

How Long Do the Results of This Knee Injectable Last?

Monovisc has been shown to provide extended relief from knee pain associated with osteoarthritis, often lasting up to 26 weeks. As a single medical treatment, it reduces friction and restores the cushioning properties of synovial fluid within the joint.

Patients typically experience gradual improvement in mobility, making everyday activities easier and less painful. The sustained results are linked to its high-viscosity formulation of cross-linked sodium hyaluronate, which improves lubrication and shock absorption in the affected knee.

Because of its durable effect, Monovisc decreases the need for repeated procedures, which benefits both patients and healthcare providers. Fewer injections translate to reduced clinic visits, lower overall treatment burden, and greater convenience. For many patients, this makes Monovisc a preferred option compared to other injectable drugs or meds that require frequent administration.

By addressing both symptom relief and functional improvement, this product stands as a valuable tool in the long-term management of osteoarthritis-related knee pain.

Is There Recovery Time Associated With MONOVISC Product?

Recovery following a Monovisc injection is typically minimal, allowing most patients to return to daily routines soon after the treatment. This injectable is delivered as a single-dose viscosupplementation procedure, reducing the need for prolonged downtime. However, physicians usually recommend:

• Avoiding strenuous activities, such as running or heavy lifting, for the first 48 hours to allow the joint to adapt to the enhanced lubrication and cushioning.

The simplicity of a single knee injection means fewer follow-up visits and less interruption to normal schedules. Unlike drugs or therapies requiring multiple applications, this product offers both medical convenience and efficiency.

Its streamlined approach makes it an attractive choice for orthopedic and medical clinics seeking effective management options for osteoarthritis-related knee pain. Patients appreciate the reduced recovery demands, which support quicker return to mobility and comfort.

Is This Sodium Hyaluronate Knee Treatment Safe?

The Monovisc injection is recognized as a safe and effective viscosupplementation option for most patients with osteoarthritis of the knee.

• The product contains high molecular weight sodium hyaluronate produced through bacterial fermentation, eliminating reliance on animal-derived materials.
• This formulation reduces the likelihood of allergic reactions and ensures compatibility for individuals sensitive to avian proteins such as feathers, eggs, or poultry. Its safety profile makes it suitable for use in both orthopedic and broader medical applications.
• While Monovisc demonstrates strong tolerability, clinicians must carefully assess each patient’s medical history before proceeding with treatment. Like other injectable drugs, it may not be recommended in cases involving active joint infections, skin disease at the injection site, or known hypersensitivity to hyaluronan-based products.

Adhering to established administration protocols ensures safe delivery and maximizes outcomes. Healthcare providers are encouraged to consult official product labeling and clinical guidelines to confirm best practices for safe use.

Contraindications

Before administering Monovisc injections, healthcare providers must carefully evaluate a patient’s medical history to identify any contraindications. Although this injection treatment is considered safe for most individuals with osteoarthritis, certain groups may face increased risks. The presence of allergies, infections, or systemic conditions can make knee injections unsuitable, and administering the product under these circumstances may lead to complications.

Clinicians should always consider the following groups as not suitable candidates for Monovisc:

• Individuals with hypersensitivity to hyaluronic acid or any other components of the product
• Patients allergic to gram-positive bacterial proteins
• Those with skin infections or open wounds near the knee injection site
• Individuals diagnosed with systemic bleeding disorders
• Pregnant or breastfeeding women
• Pediatric patients under 18 years of age

These contraindications highlight the importance of thorough clinical screening before initiating joint injection treatment. Providers should always consult the official package insert for the latest recommendations and refer patients to an orthopedic or medical specialist when uncertainties arise regarding the safe administration of hyaluronan-based drugs or products.

Potential Side Effects of MONOVISC

Like other knee injections, Monovisc may cause side effects, though most remain mild and self-limiting. Common post-procedure responses include localized swelling, discomfort, or stiffness at the joint.

These reactions are generally short-lived and reflect the body’s temporary response to the injection treatment rather than the active hyaluronic acid component. Clinical studies report that these effects usually resolve without the need for additional drugs or medical intervention.

The most frequently reported side effects include:

• Localized discomfort at the knee
• Mild joint swelling or effusion
• Temporary increase in pain
• Tenderness or soreness at the injection site

Although rare, more serious outcomes such as hypersensitivity or inflammatory responses may occur and should be addressed promptly. Practitioners administering Monovisc injections must maintain strict aseptic technique to minimize infection risks and ensure patient safety. Transparent communication with patients about possible side effects helps manage expectations and promotes confidence in this viscosupplementation treatment.

How Much Does This Product Cost?

The price of Monovisc depends on the supplier and purchasing method, but most verified distributors keep costs within a consistent range. Clinics and healthcare providers typically order Monovisc through licensed wholesale platforms such as Medica Depot, where bulk orders and clinic accounts can lead to additional savings.

This injectable hyaluronic acid product is designed for single-use knee injections, offering long-lasting relief from osteoarthritis pain with just one treatment, which adds to its overall value compared to other drugs requiring multiple doses.

• Price Range: $329–$349
• Available only through authorized orthopedic distributors and medical supply channels
• Discounts may apply for bulk orders or verified clinic accounts

By sourcing through trusted suppliers, clinics not only secure competitive Monovisc costs but also ensure product authenticity, proper storage, and compliance with medical standards. This balance of affordability, verified quality, and therapeutic efficacy makes Monovisc a reliable choice for osteoarthritis management.

Where To Order MONOVISC® Products Online

Healthcare professionals can order Monovisc online from licensed medical distributors that specialize in orthopedic and joint-care therapies. Monovisc is a high-quality, single-injection hyaluronic acid product designed to relieve pain associated with knee osteoarthritis. Unlike multi-dose treatments, this formulation delivers sustained relief with just one injection, making it an efficient choice for both patients and practitioners. Because it is classified as a Class III medical device, purchasing from authorized suppliers ensures compliance with safety regulations, proper handling, and authenticity.

Medica Depot offers healthcare providers a secure and verified platform to buy Monovisc online. Their catalog includes detailed description pages, product specifications, and transparent information about storage requirements to support confident clinical decisions. Customers can add products to their cart, review current Monovisc costs, and compare pricing options directly on the platform. Choosing a trusted distributor like Medica Depot guarantees that every unit meets strict medical standards, minimizing risks associated with counterfeit or improperly stored products.

Working with regulated suppliers also allows clinics to benefit from bulk purchasing and possible savings. This is particularly important for practices that perform recurring knee injections, as maintaining a reliable supply of authentic hyaluronic acid products ensures consistent treatment outcomes. By sourcing from Medica Depot, practitioners safeguard patient health while managing inventory efficiently.

How To Shop MONOVISC® On Medica Depot

To order Monovisc on Medica Depot, providers must first register for an account on the official website. The process requires proof of medical licensure or clinic affiliation, ensuring that only qualified professionals can access and purchase advanced orthopedic solutions. Once verified, customers can explore the full catalog, compare prices, and add products like Monovisc to their cart for streamlined checkout. This verification step protects patients and upholds the integrity of the medical supply chain.

After account approval, healthcare professionals can log in to view wholesale Monovisc costs, check for bulk savings, and place an order directly. The platform provides clear product descriptions, including syringe specifications and administration guidelines, ensuring informed purchasing decisions. Medica Depot also highlights any available price adjustments or promotions, helping clinics optimize their budgets while ensuring access to genuine supplies.

Customers benefit from responsive support services, transparent shipping policies, and secure payment options, which make the process of buying Monovisc online straightforward and reliable. With its focus on authenticity, direct sourcing, and competitive pricing, Medica Depot has become a trusted distributor for healthcare providers who rely on safe, effective knee injections for osteoarthritis management. By ordering from such an authorized source, clinics gain peace of mind, cost control, and dependable product availability.