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What Is HYMOVIS® and How Does It Work?

High molecular weight viscoelastic hyaluronan (HYMOVIS®) is a sodium hyaluronate-based hydrogel that improves the shock-absorbing and lubricating functions of synovial fluid. It does this by acting as a “cushion” that stops bones from grinding against each other.

HYMOVIS® increases joint function, protects soft tissues and cartilage, and reduces pain — especially in the case of people with severe knee osteoarthritis (OA). It is usually given after all other arthritis treatments have been tried.

What Is HYMOVIS® Used For?

HYMOVIS® is prescribed to people with meniscus knee lesions, reduced joint mobility, pain caused by knee osteoarthritis — or those who don’t get relief from physical therapy or using painkillers like acetaminophen. The regimen includes two injections that are given one week apart.

Patients can experience pain relief within 24 hours of completing the treatment. This can last up to six months — or a year in the case of patients treated with two cycles of HYMOVIS®.

Read our comprehensive article about HYMOVIS® injection frequency.

HYMOVIS® Side Effects

While HYMOVIS® is considered safe, your patient’s response to it can vary depending on any pre-existing medical conditions and their stage of joint pathology. Here are some side effects they could experience:

Headache or dizziness (12%)
Increased knee joint pain, swelling, or stiffness (0.1% to 1%)
Itching sensation around the knee (0.1% to 1%)
Numbness or tingling around the knee (0.1% to 1%)
Pain, redness, warmth, or swelling at the injection site (1%)
Back pain (1% to 10%)

HYMOVIS® can also cause serious side effects if patients are allergic to hyaluronic acid. Signs of an allergy include:

Difficulty breathing
Hives
Swelling (throat, tongue, or lips)

It’s important to advise your patients to seek emergency medical care if they experience any of these symptoms.

Who Should Not Take HYMOVIS®?

Not every patient is suited for HYMOVIS® treatment, and medical professionals must evaluate eligibility carefully.

Patients with bleeding disorders, such as hemophilia, or allergies to gram-positive bacterial proteins should not receive HYMOVIS® injections. Those with an active infection in or around the knee joint are also advised against undergoing the procedure. Additionally, HYMOVIS® should not be administered to patients who are pregnant or breastfeeding, as there is insufficient data on whether the hyaluronic acid hydrogel can pass through the placenta or into breast milk.

It is important to note that HYMOVIS® has only been tested for knee osteoarthritis, not for other joints or forms of osteoarthritis. The product is therefore not recommended for patients under the age of 21 or those seeking treatment for non-knee joint issues.

Precautions to Take When Using HYMOVIS®

Before beginning HYMOVIS® treatment, providers must follow strict guidelines to ensure safe and effective results.

Medical professionals should avoid using disinfectants that contain quaternary ammonium salts, as they may cause the HYMOVIS® hydrogel to precipitate. Furthermore, HYMOVIS® should not be used in the presence of joint effusions, as this can compromise the product’s performance and patient comfort.

Patients should be instructed to avoid strenuous physical activity following orthopedic injections. This includes refraining from running, jogging, lifting heavy weights, or engaging in contact sports for several days after each injection. Standing for extended periods (over an hour at a time) should also be avoided after receiving HYMOVIS®.

Where Can I Buy HYMOVIS®?

If you’re looking to buy HYMOVIS, it’s essential to source it from a trusted medical supplier to ensure authenticity and safety.

Manufactured by Fidia Pharmaceuticals in Italy, HYMOVIS® comes in a treatment pack containing two pre-filled syringes (3 mL each), to be administered one week apart. This provides a full course of HYMOVIS® treatment with one purchase. Licensed professionals can buy HYMOVIS online at Medica Depot, a trusted platform offering high-quality orthopedic and aesthetic solutions.

We offer the option to buy HYMOVIS wholesale, ideal for clinics and practices that treat multiple patients with knee osteoarthritis. When you buy HYMOVIS from Medica Depot, you’ll receive factory-sealed products that are shipped under safe, compliant conditions.

Treat Knee Pain with Medica Depot

If you have a patient struggling with knee pain that has not been resolved using traditional medications, physical therapy, and weight loss, HYMOVIS® may prove effective for their situation.

However, sourcing this hydrogel can be difficult. If you’re looking to buy HYMOVIS® wholesale, we can help.

At Medica Depot, we understand you need safe and effective medications to help your patients feel their best. That’s why we offer everything you might need online. Take a look through our inventory and buy HYMOVIS® today!

FAQs

Who Is an Ideal Candidate for HYMOVIS®?

Good candidates for HYMOVIS® include patients who:

Have not experienced any relief when using analgesics
Have not seen an improvement in their symptoms after physical therapy
Have lost weight but still experience severe knee pain
Prefer to avoid opioid pain medication.

Does HYMOVIS® Interact With Other Drugs?

HYMOVIS® can interact with any topical medications containing benzalkonium chloride (Alocane Max, Herpetrol, Protac) and cetylpyridinium (Bucalsep Spray and Solution).

How Soon Can You Get Pain Relief From HYMOVIS®?

Pain relief can vary depending on a patient’s joint condition, pain intensity, treatment regimen, and medical conditions. However, most patients with mild pain experience relief within 24 to 36 hours.