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Radiesse (formerly known as Radiance) is has been approved by regulatory agencies as an injectable dermal filler used to treat skin imperfections at a deeper level. This filler is most effective for moderate to severe facial wrinkles and skin volume loss.

What is Radiesse?

Radiesse is a brand of dermal fillers manufactured by Merz Aesthetics, which is a subsidiary of the Merz Pharma Group, a large multinational pharmaceutical company. Radiesse fillers are made of calcium hydroxylapatite (CaHa) microspheres; CaHa is a unique substance that can provide long-lasting skin lifting effects. Radiesse treatments are well-suited for treating skin volume loss in the back of the hands and correcting the appearance of moderate to severe facial folds and skin wrinkles or lines on the face, including nasolabial folds; accordingly, the Federal Drug Administration (FDA) has approved Radiesse fillers for these indications. In 2015, the FDA approved Radiesse fillers for use in the back of the hands to treat the loss of skin volume.

What products does the Radiesse brand consist of?

How much do they cost?

  • Radiesse 0.8ml: $169–$189
  • Radiesse 1.5ml: $225–$245
  • Radiesse (+) 0.8ml w/ Lidocaine: $188–$209
  • Radiesse (+) 1.5ml w/ Lidocaine: $244–$264

What are the benefits of Radiesse?

  • Patients attain truly exceptional results: In clinical studies, Radiesse variants have consistently left patients highly satisfied with the results of treatment. In one study, there were more patients satisfied with the results of Radiesse filler than there were patients satisfied with the results of each tested hyaluronic acid-based filler, as CaHa was found to last for longer and be more effective than any of the hyaluronic acid-containing fillers.

How long do the results of these fillers last?

The effects on skin of a Radiesse filler product can last for up to year or longer. In some cases, the results have been reported to last for up to two years.

Is there recovery time associated with Radiesse?

Minimal recovery time is required after injection of a Radiesse product.

Are they safe?

Yes, Radiesse fillers are safe products that can be confidently used on patients. With that said, Radiesse  product use may cause side effects and are contraindicated in a number of cases.


Radiesse products are contraindicated in the following types of patients:

  • patients with a hypersensitivity to CaHa or any filler ingredient
  • patients with a bleeding disorder
  • patients with a history of severe allergies or anaphylaxis
  • patients that are pregnant or bleeding.

These may not be all the contraindications for Radiesse product use. Some Radiesse products may have different contraindications from other products in the brand. Refer to the package insert of a Radiesse product for more information on its contraindications, or check online.

Side Effects

The side effects Radiesse product use can cause include but are not limited to the following: redness, swelling, bruising, pain.


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