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HYALGAN®, a reputable brand in the field of orthopedic medicine, specializes in providing sodium hyaluronate-based injections for the treatment of osteoarthritis knee pain. These injections, known for their viscosupplementation properties, are designed to mimic the natural hyaluronic acid in the knee joint, offering pain relief and improving mobility. You can buy HYALGAN® products on Medica Depot. Read more about their therapeutic uses, mechanism of action, potential side effects, and product availability.


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What Is Hyalgan Injection?

Hyalgan is a prescription orthopedic injectable that contains sodium hyaluronate, a natural substance found in the body’s synovial fluid. It is widely used for pain relief in patients with knee osteoarthritis and other joint-related conditions. By supplementing the body’s natural hyaluronic acid, Hyalgan helps improve lubrication and cushioning within the joint, easing movement and reducing discomfort.

Manufactured by Fidia Farmaceutici S.p.A., an Italian medical and pharmaceutical company, Hyalgan is recommended for osteoarthritis of the knee in mild to moderate stages. It works by restoring the viscoelastic properties of synovial fluid, which supports joint pain management, slows down cartilage wear, and improves mobility. These benefits make it a valuable non-surgical option before considering more invasive procedures such as total joint replacement.

How HYALGAN Helps Improve Joint Health

By increasing the density and viscosity of synovial fluid, Hyalgan injections:

  • Protect cartilage tissue from further damage
  • Reduce load and friction between joint surfaces
  • Lower inflammation in the synovial lining
  • Slow progression of degenerative changes
  • Support nourishment and repair of cartilage

Conditions Treated with HYALGAN

Medical professionals may prescribe Hyalgan for:

  • Acute joint pain and inflammation
  • Arthritis and arthrosis
  • Gout-related joint discomfort
  • Bursitis, synovitis, or tendinitis
  • Recovery after joint injury or arthroscopy
  • Tunnel syndrome or adhesive capsulitis

How Does HYALGAN Work On The Knee?

Intra-articular Hyalgan injections can help patients avoid joint replacement surgery if treatment begins early in the disease process. Sodium hyaluronate in Hyalgan mimics the body’s natural hyaluronic acid, which is essential for maintaining synovial fluid’s viscosity and elasticity. It also supports the formation of proteoglycans in cartilage, essential for joint resilience and flexibility.

By restoring synovial fluid quality and promoting cartilage renewal, Hyalgan enhances joint function, allowing smoother movement and less pain. It also helps to reduce inflammation in the synovial lining while stimulating the joint’s own production of hyaluronic acid.

After injection, Hyalgan is metabolized efficiently in the body. It is detectable in synovial fluid within 2 hours and in cartilage within 6 hours, where it remains active for extended periods.

The liver processes the majority of the medication, with approximately 42% of the administered dose eliminated in urine within 24 hours. This targeted retention in cartilage makes Hyalgan a highly effective orthopedic injectable for knee osteoarthritis management.

Ingredients Used In HYALGAN

Hyalgan contains the active substance sodium hyaluronate, a purified form of hyaluronic acid naturally found in the body’s synovial fluid. Each 2 mL prefilled syringe delivers 20 mg of sodium hyaluronate in sterile solution. This compound plays a critical role in lubricating and cushioning the joints, making it essential for reducing pain and improving mobility in patients with knee osteoarthritis. By replenishing the body’s natural hyaluronic acid levels, Hyalgan supports joint health and function, helping restore smoother and more comfortable movement.

In addition to the active ingredient, Hyalgan contains specific excipients to maintain stability and ensure safe intra-articular injections. These include:

  • Sodium chloride
  • Sodium dihydrogen phosphate dihydrate
  • Sodium hydrogen phosphate dodecahydrate
  • Water for injections

According to the official prescribing information, this carefully balanced formulation ensures optimal viscosity for injection, enhances the lubricating properties of the solution, and supports the therapeutic effectiveness of Hyalgan in osteoarthritis treatment.

How To Use Hyalgan Sodium Hyaluronate Injection

Administration of Hyalgan injectable must be performed only by a qualified orthopedic surgeon or orthopedic traumatologist. These intra-articular injections require:

  • Precise placement into the knee joint space, and ultrasound guidance is often used to ensure accuracy.
  • In some cases, the physician may aspirate (remove) excess synovial fluid from the joint before injecting the medication; this fluid may be sent for laboratory analysis to assess joint health.
  • Immediately after the ml injection, patients are usually encouraged to perform light physical exercises to help distribute the hyaluronic acid evenly within the joint.

The treatment schedule is individualized based on the patient’s specific condition and response to therapy. Typically, a treatment course lasts up to one year, with injections given at intervals of 1 to 2–3 weeks, or as frequently as 3–5 per week in some protocols.

The therapeutic aim is to reduce pain, improve mobility, and restore normal joint function in patients suffering from knee osteoarthritis.

Possible Side Effects of HYALGAN

Although Hyalgan is generally well tolerated, some patients may experience mild and temporary side effects at the injection site. These may include:

  • Pain, redness, or slight swelling at the injection site
  • Itching or burning sensations after injection
  • Minor bleeding into the joint cavity
  • Discomfort in tissues surrounding the joint
  • Localized skin hematoma at the injection site

These effects typically resolve on their own within a few days. If symptoms persist or worsen, patients should promptly consult their healthcare provider for further evaluation.

HYALGAN Aftercare

After receiving a Hyalgan injection, patients should follow specific aftercare instructions to maximize treatment benefits and reduce the risk of side effects.

  • For the first 48 hours, avoid strenuous activities or high-impact exercise involving the knee. This rest period allows the sodium hyaluronate solution to settle in the joint space and work effectively.
  • Applying an ice pack for 10–20 minutes every 1–2 hours during the first two days can help reduce swelling and discomfort.
  • Healthcare providers may also recommend over-the-counter medications, such as acetaminophen or ibuprofen, to manage post-procedure pain.
  • It is essential to keep the injection site clean and dry to prevent infection.
  • Patients should avoid touching the treated area unnecessarily and should not apply creams, lotions, or ointments unless directed by their healthcare provider.

Proper aftercare supports the healing process and enhances the effects of the hyaluronic acid in Hyalgan, leading to improved mobility and reduced joint pain.

How Long Does HYALGAN Last?

Clinical studies and Hyalgan patient reports indicate that this treatment can provide significant pain relief for up to six months in individuals with knee osteoarthritis.

  • The standard protocol involves a series of five syringes administered at one-week intervals. This structured dosing schedule allows the hyaluronic acid in Hyalgan to effectively restore joint lubrication, cushion the cartilage, and reduce inflammation over time.

Treatment results vary based on factors, such as:

  • The severity of the condition
  • Adherence to aftercare
  • Individual response to therapy

Patients should discuss ongoing management plans with their healthcare provider, who may recommend follow-up courses or additional supportive medications as needed. Maintaining a healthy weight, engaging in low-impact exercise, and following medical guidance can help prolong the benefits of Hyalgan and delay the progression of knee osteoarthritis.

Is HYALGAN Safe?

Hyalgan is generally considered safe when administered by a qualified healthcare provider; however, there are important contraindications to consider, which include:

  • Patients who are pregnant, breastfeeding, under the age of 18, or have active infectious diseases should not undergo this treatment.
  • It is also not recommended during acute joint inflammation, in the presence of skin diseases over the knee joint, or if the skin at the injection site is broken.
  • Additionally, individuals with known hypersensitivity to sodium hyaluronate or any excipients in the formulation should avoid the procedure, as it may cause allergic reactions.

To minimize potential risks, only obtain Hyalgan from certified suppliers. If you choose to buy Hyalgan online, ensure it comes from trusted distributors, such as Medica Depot, to guarantee product authenticity and safety.

Doctors will evaluate your medical history and current health status before recommending the use of Hyalgan syringes, ensuring the hyaluronic acid-based therapy will not negatively impact your overall health.

HYALGAN Benefits

Hyalgan provides several therapeutic advantages for patients suffering from knee osteoarthritis. Administered via intra-articular injections, the sodium hyaluronate solution helps replenish the natural hyaluronic acid found in the joint, restoring lubrication and cushioning to the affected area. This process reduces friction between cartilage surfaces, decreases inflammation, and alleviates pain, ultimately supporting improved joint mobility.

Beyond immediate pain relief, Hyalgan can contribute to long-term joint health when used as part of a comprehensive management plan. Many patients experience sustained improvement in movement and comfort, which enhances their ability to engage in daily activities without dependence on oral medications for pain control.

By improving the quality of synovial fluid and supporting cartilage health, Hyalgan offers a targeted, non-surgical treatment option for those seeking relief from degenerative joint disease.

Buy HYALGAN Wholesale At Trusted Suppliers

Healthcare professionals looking to buy Hyalgan should ensure they purchase only from reputable distributors who sell authentic Hyalgan products with verified LOT numbers.

At trusted suppliers, every batch is sourced according to strict quality and safety guidelines, ensuring compliance with the official label and manufacturer data. If needed, customers can request LOT number confirmation before placing their orders.

Purchasing in bulk allows clinics to benefit from savings while maintaining a consistent supply of Hyalgan injections for patient care. Joint pain, particularly from knee osteoarthritis, can greatly reduce a patient’s quality of life, limiting mobility and daily function.

By sourcing genuine supplies from reliable distributors, healthcare providers can offer safe and effective treatments that help patients regain comfort and movement.

Order HYALGAN Online At Medica Depot

Licensed medical professionals can confidently buy Hyalgan online through Medica Depot, a trusted and globally recognized distributor. Their secure site offers easy ordering, transparent pricing, and access to genuine Hyalgan products with competitive wholesale rates.

The customer service team can assist with prescription verification, supplies management, and order tracking to ensure smooth delivery.

Medica Depot also offers:

  • Free or discounted shipping options for eligible orders
  • Access to customer reviews for informed purchasing decisions
  • Comprehensive product data and official manufacturer label information
  • Wholesale savings for bulk orders

By choosing Medica Depot, healthcare providers can be assured they are receiving authentic, high-quality Hyalgan injections that adhere to regulatory standards. This combination of trusted sourcing, documented safety, and strong customer support helps clinics manage their treatment inventory efficiently while keeping costs under control.

 

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