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ACTEMRA® (tocilizumab) is a recombinant humanized monoclonal antibody directed against the interleukin-6 (IL-6) receptor. It is indicated for the treatment of autoimmune inflammatory conditions, including moderately to severely active rheumatoid arthritis (RA) in adults, polyarticular juvenile idiopathic arthritis (PJIA), and systemic juvenile idiopathic arthritis (SJIA) in pediatric patients aged ≥2 years. ACTEMRA® may be administered via intravenous infusion or subcutaneous injection, depending on the indication and formulation. If you want to buy ACTEMRA® for your practice today, contact the customer service representatives on Medica Depot.


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What is ACTEMRA?

ACTEMRA (tocilizumab) is a biologic medication designed to reduce immune system overactivity by blocking interleukin‑6 (IL‑6) receptors. It is prescribed for rheumatoid arthritis (RA), giant cell arteritis (GCA), systemic juvenile idiopathic arthritis (SJIA), polyarticular juvenile idiopathic arthritis (PJIA), cytokine release syndrome (CRS), and severe COVID‑19 inflammation.

Clinicians can buy ACTEMRA in small and medium vial sizes, ensuring flex administration for patients of different heights and body weights, including those over 100 kg. ACTEMRA’s background as a well‑researched biologic ensures strong clinical visibility, and its dosing padding allows safe adjustments for individualized treatment. By stimulating better immune regulation, ACTEMRA’s benefits include reducing inflammation, protecting joint structures, and improving long‑term quality of life.

Providers can order ACTEMRA with clear inventory visibility, choosing the correct size and flex dosing for their practice.

Key Benefits of ACTEMRA

ACTEMRA’s effectiveness comes from blocking the IL‑6 receptor, which interrupts the inflammatory cascade. These benefits are especially valuable for both small and medium patient populations:

  • Reduces joint swelling, tenderness, and disease activity in RA, SJIA, and PJIA, supporting optimal treatment visibility

  • Improves ACR scores, CRP levels, and symptom tracking via clinical slider measurements

  • Works as monotherapy or with other non‑biologic DMARDs for dosing flex

  • Slows joint damage progression, backed by strong background clinical studies

  • Flexible size options and dosing padding for patients under or over 100 kg

  • Provides dual IV and SC administration, improving home‑care visibility and patient adherence

Healthcare professionals can confidently buy ACTEMRA knowing that its clinical filter ensures reliable safety and efficacy for small or medium practices.

ACTEMRA Product Range

ACTEMRA’s product size and flex design allow precise dosing for various patient heights, weights, and clinical needs.

  • ACTEMRA 80 mg/4 mL (IV): Small vial for pediatric or low‑weight dosing

  • ACTEMRA 200 mg/10 mL (IV): Medium size, ideal for standard adult RA therapy

  • ACTEMRA 400 mg/20 mL (IV): High volume for patients over 100 kg

  • ACTEMRA 162 mg/0.9 mL Prefilled Syringe (SC) : Convenient flex for at‑home self‑injection

When you order ACTEMRA, selecting the right size ensures smooth workflow padding, better inventory visibility, and safe patient care.

Clinical Indications for ACTEMRA

ACTEMRA is FDA‑approved for:

  • Rheumatoid Arthritis (RA): Moderate to severe active RA in adults

  • Giant Cell Arteritis (GCA): Adults with large vessel vasculitis

  • Systemic Juvenile Idiopathic Arthritis (SJIA): Pediatric patients ≥2 years

  • Polyarticular Juvenile Idiopathic Arthritis (PJIA): Pediatric patients ≥2 years

  • Cytokine Release Syndrome (CRS): After CAR‑T therapy

  • Severe COVID‑19 Inflammation: Hospitalized patients under strict monitoring

By offering small and medium vial sizes, ACTEMRA’s flex options allow precise dosing with clinical visibility for all patient heights.

ACTEMRA Ingredients

Understanding ACTEMRA’s background helps ensure treatment visibility and safety:

  • Active Ingredient: Tocilizumab – Humanized anti‑IL‑6 receptor monoclonal antibody

  • Excipients: L‑histidine, polysorbate 80, L‑arginine, L‑methionine, and sterile water for injection

All vials are single‑use, sterile, preservative‑free, and labeled for clear size recognition. Clinics that buy ACTEMRA benefit from inventory filter control, ensuring the right padding for both small and medium dosing schedules.

ACTEMRA Administration Technique

ACTEMRA offers flex administration with both IV and SC routes, suitable for small or medium patients by size and height.

Intravenous (IV)

  • 60‑minute infusion, diluted in 50 mL (<30 kg) or 100 mL (≥30 kg) 0.9% NaCl

  • RA: 4–8 mg/kg every 4 weeks

  • PJIA/SJIA: 8–12 mg/kg based on weight

Subcutaneous (SC)

  • <100 kg: 162 mg every 2 weeks, adjustable to weekly

  • ≥100 kg: 162 mg weekly

  • Can be self‑administered after training

Correct dosing padding, filter checks, and monitoring via a clinical slider improve treatment visibility and outcomes.

ACTEMRA Storage Conditions

To maintain ACTEMRA’s background quality:

  • Store at 2°C to 8°C (36°F to 46°F)

  • Keep in original padding for light protection

  • Do not freeze

  • Use diluted IV solution within 24 hours

Maintaining proper visibility over storage conditions ensures small and medium practices can buy ACTEMRA and manage inventory efficiently.

ACTEMRA Side Effects

Providers must monitor ACTEMRA’s side effects with clear visibility:

Common:

  • Upper respiratory infections, headache, hypertension

  • Mild liver enzyme elevations

  • Injection site reactions (SC only)

Serious:

  • Pneumonia, cellulitis, shingles

  • Gastrointestinal perforation (especially in RA with diverticulitis)

  • Neutropenia, hepatotoxicity, hyperlipidemia

  • Anaphylaxis or hypersensitivity reactions

Using a clinical slider or patient tracking filter ensures early detection and safe dosing flex adjustments.

Buy ACTEMRA Online

Clinics can buy ACTEMRA or order bulk inventory with full visibility for small or medium practice needs. Actemra’s different sizes, background of safety, and dosing flex make it a reliable choice.

When you order ACTEMRA, select the correct vial size—80 mg, 200 mg, 400 mg, or 162 mg PFS—for optimal padding and patient height flexibility.

Contact authorized distributors like Medica Depot to buy ACTEMRA today and benefit from streamlined supply visibility, clinical filtering, and efficient workflow flex.

 

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