LUMIGAN®

Key Benefits of LUMIGAN®

LUMIGAN® demonstrates significant efficacy in lowering IOP, with effects comparable or superior to other topical prostaglandin analogs. Its pharmacological profile provides sustained pressure reduction with once-daily administration.

• Mean reduction of IOP: 7–8 mmHg with 0.03% formulation

• Reduction of IOP: up to 7.5 mmHg with 0.01% formulation

• Onset of action: within 4 hours of first administration

• Maximum effect: achieved within 8–12 hours

• Maintains stable safety profile over 12 months of treatment

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Clinical Indications for LUMIGAN®

LUMIGAN® is prescribed for ocular conditions associated with increased intraocular pressure. The clinical aim is to prevent glaucomatous progression and optic nerve compromise.

• Primary open-angle glaucoma

• Ocular hypertension

• Not evaluated for angle-closure glaucoma, neovascular glaucoma, or inflammatory glaucoma

• Recommended only in adult patients, as pediatric use (<16 years) is not advised due to pigmentation risk

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LUMIGAN® Ingredients

The formulation consists of the active agent and excipients to ensure isotonicity, pH stability, and sterility.

• Active substance: Bimatoprost 0.1 mg/mL (0.01%) or 0.3 mg/mL (0.03%)

• Preservative: Benzalkonium chloride (0.2 mg/mL in 0.01%; 0.05 mg/mL in 0.03%)

• Inactive components: Sodium chloride, sodium phosphate (dibasic), citric acid, purified water

• pH adjustment: Sodium hydroxide and/or hydrochloric acid

• pH range during shelf life: 6.8–7.8

• Osmolality: approximately 290 mOsmol/kg

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LUMIGAN® Product Range

The product is supplied in sterile ophthalmic dispensers of varying capacities, designed to maintain solution stability and sterility during patient use.

• 0.01% formulation:

  • 2.5 mL in 5 mL container

  • 5 mL in 10 mL container

  • 7.5 mL in 10 mL container

• 0.03% formulation:

  • 2.5 mL in 5 mL container

  • 5 mL in 10 mL container

  • 7.5 mL in 10 mL container

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LUMIGAN® Administration Technique

Correct administration technique ensures optimal therapeutic effect and minimizes contamination risk.

• Recommended dosage: one drop in the affected eye(s), once daily in the evening

• More frequent dosing may reduce IOP-lowering efficacy

• If multiple ophthalmic drugs are used, administer at least 5 minutes apart

• Contact lenses should be removed prior to instillation; reinsert after 15 minutes

• Avoid contact of dropper tip with ocular surfaces to prevent bacterial keratitis

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LUMIGAN® Storage Conditions

To preserve efficacy and sterility, LUMIGAN® must be stored under controlled conditions.

• Storage range: 2°C–25°C (36°F–77°F)

• Supplied in opaque low-density polyethylene bottles with protective caps

• Protect from contamination by maintaining container integrity

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LUMIGAN® Side Effects

Adverse reactions are primarily ocular, though systemic effects are also reported. Monitoring is recommended during long-term therapy.

• Very common (≥25%): conjunctival hyperemia

• Common (>10%): eyelash growth, ocular pruritus

• Occasional (1–10%): ocular dryness, irritation, burning, blepharitis, pigmentation of periocular skin, cataract, keratitis, photophobia, tearing, allergic conjunctivitis

• Rare (<1%): intraocular inflammation (iritis)

• Systemic: upper respiratory tract infections (~10%), headache, abnormal liver function tests (1–5%)

• Pigmentation: iris pigmentation may be permanent; eyelid and eyelash pigmentation may be reversible after discontinuation

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Read our dedicated article about LUMIGAN side effects.

Buy LUMIGAN® Online

Healthcare institutions and licensed providers can buy LUMIGAN® online or order LUMIGAN® wholesale through regulated distribution channels. Online procurement enables access to multiple formulations and package sizes for clinical use. When ordering, professionals should ensure compliance with pharmaceutical regulations and storage requirements.

• Options to order LUMIGAN® online in both 0.01% and 0.03% strengths

• Suitable for hospital pharmacies, ophthalmology clinics, and specialized practices

• Wholesale availability supports bulk purchasing for long-term therapy management

FAQs About LUMIGAN®

Here’s a list of the most commonly asked questions about Lumigan.

What is the mechanism of action of LUMIGAN®?

LUMIGAN® lowers intraocular pressure by increasing aqueous humor outflow through both trabecular meshwork and uveoscleral routes.

How quickly does LUMIGAN® act?

IOP reduction begins within 4 hours, reaching maximum effect between 8–12 hours.

Can patients use LUMIGAN® with contact lenses?

Yes, but lenses should be removed prior to instillation and reinserted 15 minutes later due to benzalkonium chloride absorption.

Is LUMIGAN® safe in children?

Use in patients under 16 years is not recommended due to risk of permanent pigmentation changes.

What precautions are necessary?

Caution in patients with uveitis, aphakia, torn posterior lens capsule, or risk factors for macular edema.