Botox

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Disclaimer:

Botox products are intended for professional use and only aesthetic doctors, plastic surgeons, and beauty clinics can order Botox online. Independent unprofessional use of these products may cause harm to your health.

What is Botox?

For many years, injectable cosmetic procedures have been gaining popularity, and Botox injections are one of the most popular procedures in aesthetic cosmetology.

Botox is one of the easiest and most reliable ways to rejuvenate the face; it minimizes wrinkles and crow’s feet and can lift the eyebrows.

Botox is a brand name for the botulinum neurotoxin (botulinum toxin) drug manufactured by Allergan. The name “Botox” has long been the “number 1” name in the world of cosmetology, as it is recognized as a calling for any injected neurotoxin, regardless of the botulotoxin manufacturer.

Botulinum toxin type A is an organic substance produced by Clostridium Botulinum bacteria without oxygen.

The product belongs to the muscle relaxants category, providing a potent muscle blockade but, at the same time, having a limited effect. The result of its application is manifested only in the places of introduction.

Botox does not migrate into neighboring tissues, does not affect the work of internal organs and systems, and does not cause allergic reactions and deterioration of well-being.

The product is intended for intramuscular administration, which is carried out with the help of a thin needle. Only minor traces and hematomas remain in the injection areas, and these reactions pass within a few days.

After the introduction of Botox, there is a direct inhibition of muscle fibers at the level of the neuromuscular synapse and a decrease in the activity of muscle stretch receptors.

In 2002, Botox was approved and began to improve and relax wrinkles between the eyes on the forehead. Since then, it has been successfully used in aesthetic cosmetology.

In 2004, Botox was approved for the treatment of excessive sweating (hyperhidrosis), and in 2010 – for the treatment of migraine headaches.

For medical purposes, in addition to ophthalmology, it is used for various diseases, such as:

• • Cerebral palsy
• • Torticollis
• • After a stroke
• • It is injected into the armpits and inguinal areas to prevent excessive sweating
• • To eliminate facial asymmetry caused by some diseases.

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The Principle Of Botox’s Action

The main effect is achieved due to the use of a complex botulinum toxin type A (Clostridium botulinum). Once inside the body, this complex breaks down, releasing pure neurotoxin.

Botulinum toxin molecules consist of linked heavy (with a molecular weight of 100,000 Da) and light (with a molecular weight of 50,000 Da) chains.

The heavy chain binds to specific receptors located on the surface of target neurons. And the light one has protease activity that manifests itself in cytoplasmic areas. Thanks to this, botulinum toxin molecules bind to neuromuscular cells.

When injected, the medicine affects the nerve endings that transmit commands to the muscles, temporarily blocking them. Blockade of the acetylcholine release leads to a decrease in the activity of muscle receptors: the dynamic muscle does not contract but relaxes.

This ensures the elimination of facial wrinkles and the cessation of migraines and hyperhidrosis.

What Is Botox Used For?

Cosmetological problems that can be solved using Botox:

• • horizontal and transverse forehead wrinkles
• • wrinkles between the eyebrows (“furrows of anger”)
• • folds on the bridge of the nose
• • wrinkles in the corners of the eyes (“crow’s feet”)
• • wrinkles above and below the lips
• • increased sweating of palms, armpits, and feet.

What Happens During The Botox Procedure?

Botox treatment can be carried out only by licensed specialists with special training and a certificate from the Botox manufacturer.

First, you conduct an examination of the patient to determine the presence of indications and contraindications for Botox injections.

Then you get the client elevated on the cosmetology couch and clean the injection areas with an antiseptic before starting the procedure.

For pain relief, you need to use a local anesthetic.

The medical solution needs to be prepared immediately before the procedure. It is forbidden to open the bottle by completely removing the rubber stopper, and the central part of the stopper has to be pretreated with alcohol.

The bottle’s content should be diluted in 2-4 ml of 0.9% sodium chloride solution for injection. The solution is carefully introduced into the vial and thoroughly mixed for 1 minute.

The result is a transparent or slightly yellow liquid without extraneous inclusions.

The prepared Botox solution can be stored for 4 hours at a temperature of 2 to 8 degrees Celsius. A syringe with a needle diameter of 0.27-0.29 mm is required to inject Botox into the tissue.

After the procedure, the remaining solution is inactivated with the help of sodium hypochlorite (which contains 1% active chlorine). All materials should be disposed of according to the rules for biological waste disposal.

There are several methods of product administration. The cosmetologist chooses the most suitable of them, depending on the goals and nature of the problems: the number of wrinkles, depth, and location. The medicine is administered directly at the site of the intended action.

The result of the Botox application is noticeable immediately; however, the full effect will be achieved only after two weeks. After repeated injections, 1-5% of patients develop antibodies to botulinum toxin type A, so the product’s effectiveness may be reduced.

A noticeable cosmetic effect occurs 5-7 days after the procedure and lasts up to 6 months. To maintain the result, after this period, injections should be repeated. During the effect of Botox, the patient gets rid of the habit of wrinkling the face, and even after the procedures are stopped, the wrinkles become less visible.

How Long Does Botox Last?

After 3-6 months, the effect of the Botox administration disappears, and the muscles begin to work with the same intensity. For some patients, a sufficient interval is 4-6 months.

Is Botox Safe?

One of the main conditions for using Botox is absolute freshness, so it is essential to hold on to the storage rules. The medicine must be stored in a refrigerator and diluted immediately before administration.

It is crucial to know that the expiration term of Botox in a diluted state is up to 4 hours.

The package should be opened directly in front of the patient.

Botox’s Main and Side Effects

Most of the minuses of Botox are myths and rumors, the use of low-quality medicine, and insufficient qualifications of the doctor who performed the procedure. Because of this, negative consequences of BTA injections, including the use of an unreasonably high dose of the product, are possible. But the benefits of Botox overshadow these disadvantages.

Botox Main Effect

There are the following advantages of Botox treatment:

• • Rejuvenation without surgical intervention. Most plastic surgeries that give a pronounced effect (lifts, blepharoplasty, lip filling, otoplasty, etc.) require rehabilitation.
• • Natural facial expressions are preserved. Turning a face into a mask is a common myth. With proper botulinum therapy, the absence of negative consequences is guaranteed.
• • Immediate effect. After just a few days, patients receive a visible result of Botox injections. The accumulative properties of the product work with regular injections.
• • Minimal pain sensations. The procedure is painless for most patients, as ultra-thin needles are used for injection.
• • Botox can be used in combination with plastic surgery and other rejuvenation procedures.

An additional advantage is the affordable Botox cost and speed of procedures. Even if there are several problem areas for processing, the total duration of manipulations will be at most 10-15 minutes.

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Botox Contraindications

There are several contraindications for Botox injections:

• • Myasthenia
• • Blood clotting disorders
• • Inflammatory and/or infectious process in the areas of intended injections
• • General diseases in the acute stage
• • Taking medicines, such as antibiotics, anticoagulants, antiplatelets, diazepam, and baclofen
• • Chronic obstructive lung diseases
• • Pregnancy and breastfeeding period
• • Minor age
• • First days of the menstrual cycle.

Also, 0.1% of people have experienced botulism and are therefore insensitive to botox.

All these are the most apparent medical contraindications, which apply not only to the use of Botox but also to many other products in the field of cosmetology.

Botox Side Effects

After this procedure, the main side effect is the lack of facial expressions when facial muscles seem to freeze for some time.

If Botox is administered incorrectly or due to the patient’s individual characteristics, a slight asymmetry may occur: the eyebrows will drop a bit, or the eyes might appear asymmetric. However, after 4-6 months, this will pass due to the expiration of the medicine in the body.

Rare possible complications after Botox injection include the following:

• • Pain, bruising, or swelling at the injection site
• • Headache
• • Flu-like symptoms
• • Droopy eyelid or cockeyed eyebrows
• • Crooked smile or drooling
• • Eye dryness or the opposite – excessive tearing.

Botox Aftercare

The post-procedural period is no less critical and depends on the patient’s compliance with the rules. About 4 hours after the procedure, they should maintain a vertical body position (do not lie down or tilt their head) and avoid drinking much water.

During the day, it is recommended to refrain from applying make-up, not to come into contact with water, and not to engage in physical activities.

Within two weeks after leaving the doctor’s office, it is prohibited to do the following:

• • Take vitamins of group B, antibiotics, and alcohol
• • Visit saunas or take baths
• • Sunbathe under the sun or in the salon
• • To massage the face
• • Do sports.

What is Botox Made Of?

Botox is produced in the form of a lyophilisate for the preparation of a solution. The manufacturer offers bottles of 100 or 200 activity units.

The product units are specific and cannot be compared with the units of other products based on botulinum toxin type A.

Botox ingredients:

• • Complex botulinum toxin type A (hemagglutinin) – 100 (200) units
• • Human plasma albumin – 500 μg
• • Sodium chloride – 900 μg.