CJC-1295 – No DAC (10mg)
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99% PURITY GUARANTEE
99% PURITY GUARANTEE
Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.
Preparation & Handling Notice
The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.
RESEARCH USE ONLY
This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.
Strength: 10 mg
CAS: 863288-34-0
Chemical Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular weight: 3367.9 g/mol
Peptide Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
Synonyms: MOD-GRF(1-29), CJC-1295 without DAC, modgrf, tetrasubstituted grf, modified grf
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
CJC-1295 – No DAC, also called Modified GRF (1-29), is a synthetic GHRH analog used in research on GH/IGF 1 axis–related signaling and endocrine pathway biology. “No DAC” indicates it lacks the albumin-binding drug-affinity complex found in long-acting CJC-1295 variants, making it a short-acting research peptide. It is primarily used for time-course and signaling studies in experimental designs that require shorter-duration exposures.
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INFORMATION
What is CJC-1295 – No DAC (10mg)?
CJC-1295 – No DAC (10mg) is a synthetic growth hormone–releasing hormone (GHRH) analog used in laboratory research to study endocrine signaling and growth hormone (GH) pathway biology. Within endocrine and metabolic peptide research, it is typically classified as a GHRH analog, reflecting its role as a tool for probing GH-axis–related mechanisms.
The “No DAC” version of CJC-1295 lacks the Drug Affinity Complex (DAC) found in long-acting variants, making it a short-acting peptide. This format is useful in experimental designs where a shorter-acting peptide profile is preferred for time-course and signaling studies.
Product Specifications
- CAS Number: 863288-34-0
- Category: Peptide
- Subcategory: Muscle Growth & Performance Peptides
- Chemical Formula: C₁₅₂H₂₅₂N₄₄O₄₂
- Molecular Weight: 3367.9 g/mol
- Peptide Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
- Purity: ≥99%
- Packaging Format: 10 mg
- Storage Conditions: Store at -20°C, avoid light exposure
- For Laboratory Research Use Only
Key Characteristics of CJC-1295 – No DAC (10mg)
- Defined GHRH-analog peptide: Used as a controlled research tool in GH-axis signaling studies.
- “No DAC” format: Lacks the DAC extension used in long-acting constructs, supporting study designs that benefit from shorter-duration exposure profiles.
- High purity (≥99%): Intended to reduce confounding from impurities in analytical and cell-based workflows.
- Research-only positioning: Used in non-clinical laboratory settings for mechanistic and measurement-focused studies.
- Cold storage + light protection required: Basic handling expectations to help preserve peptide integrity prior to experimental use.
- Frequently used in cell-based and preclinical model systems to study GHRH receptor activation, downstream signaling cascades, and GH-axis biomarker responses under defined conditions.
How CJC-1295 – No DAC (10mg) Supports Research
CJC-1295 – No DAC is commonly used to examine GHRH receptor–linked signaling and downstream GH-axis biomarkers in controlled models. Because it is referenced as a GHRH analog in analytical and preclinical literature, it can serve as a test article for labs evaluating pathway responses over time, comparing peptide analogs, or validating detection and characterization methods for GHRH-related compounds.
Research Applications & Usage Information
CJC-1295 – No DAC (10mg) is commonly referenced in research contexts such as:
- Endocrine signaling studies: Used in research programs examining GHRH‑linked signaling and GH-axis pathway behavior in controlled in‑vitro and preclinical systems.
- Time-course experiments: “No DAC” versions are often selected for designs where researchers want clearer timing separation between exposures and readouts.
- Comparative peptide research: Included in side-by-side studies comparing GHRH analogs or related peptides for assay response differences (model-dependent).
- Analytical method development: Used in workflows that require characterization of GHRH analogs (e.g., mass-spectrometry–based identification approaches).
- Biomarker-focused assays: Incorporated into experiments tracking GH-axis–associated markers under controlled conditions (endpoint-dependent).
Handling and Storage Recommendations
- Store at -20°C and protect from light when not in use.
- Keep the container tightly sealed to reduce exposure to moisture and ambient contaminants.
- Minimize temperature cycling (repeated warm/cool changes) to help reduce degradation risk.
- Use standard laboratory PPE and follow your facility’s SOPs for peptide reagents.
- Dispose of materials properly in accordance with institutional and local regulatory requirements.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Hartvig RA, Holm NB, Dalsgaard PW, Reitzel LA, Müller IB, Linnet K. Identification of peptide and protein doping related drug compounds confiscated in Denmark between 2007-2013. Scandinavian Journal of Forensic Science. 2014;20(2):42-49. doi:10.2478/sjfs-2014-0003
- Knoop A, Thomas A, Fichant E, Delahaut P, Schänzer W, Thevis M. Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS. Anal Bioanal Chem. 2016;408(12):3145-3153. doi:10.1007/s00216-016-9377-3
- Memdouh S, Gavrilović I, Ng K, Cowan D, Abbate V. Advances in the detection of growth hormone-releasing hormone synthetic analogs. Drug Test Anal. 2021;13(11-12):1871-1887. doi:10.1002/dta.3183
- Thomas A, Walpurgis K, Thevis M. Chromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples. J Mass Spectrom. 2024;59(1):e4996. doi:10.1002/jms.4996
What is CJC-1295 – No DAC (10mg)?
CJC-1295 – No DAC (10mg) is a synthetic growth hormone–releasing hormone (GHRH) analog used in laboratory research to study endocrine signaling and growth hormone (GH) pathway biology. Within endocrine and metabolic peptide research, it is typically classified as a GHRH analog, reflecting its role as a tool for probing GH-axis–related mechanisms.
The “No DAC” version of CJC-1295 lacks the Drug Affinity Complex (DAC) found in long-acting variants, making it a short-acting peptide. This format is useful in experimental designs where a shorter-acting peptide profile is preferred for time-course and signaling studies.
Product Specifications
- CAS Number: 863288-34-0
- Category: Peptide
- Subcategory: Muscle Growth & Performance Peptides
- Chemical Formula: C₁₅₂H₂₅₂N₄₄O₄₂
- Molecular Weight: 3367.9 g/mol
- Peptide Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
- Purity: ≥99%
- Packaging Format: 10 mg
- Storage Conditions: Store at -20°C, avoid light exposure
- For Laboratory Research Use Only
Key Characteristics of CJC-1295 – No DAC (10mg)
- Defined GHRH-analog peptide: Used as a controlled research tool in GH-axis signaling studies.
- “No DAC” format: Lacks the DAC extension used in long-acting constructs, supporting study designs that benefit from shorter-duration exposure profiles.
- High purity (≥99%): Intended to reduce confounding from impurities in analytical and cell-based workflows.
- Research-only positioning: Used in non-clinical laboratory settings for mechanistic and measurement-focused studies.
- Cold storage + light protection required: Basic handling expectations to help preserve peptide integrity prior to experimental use.
- Frequently used in cell-based and preclinical model systems to study GHRH receptor activation, downstream signaling cascades, and GH-axis biomarker responses under defined conditions.
How CJC-1295 – No DAC (10mg) Supports Research
CJC-1295 – No DAC is commonly used to examine GHRH receptor–linked signaling and downstream GH-axis biomarkers in controlled models. Because it is referenced as a GHRH analog in analytical and preclinical literature, it can serve as a test article for labs evaluating pathway responses over time, comparing peptide analogs, or validating detection and characterization methods for GHRH-related compounds.
Research Applications & Usage Information
CJC-1295 – No DAC (10mg) is commonly referenced in research contexts such as:
- Endocrine signaling studies: Used in research programs examining GHRH‑linked signaling and GH-axis pathway behavior in controlled in‑vitro and preclinical systems.
- Time-course experiments: “No DAC” versions are often selected for designs where researchers want clearer timing separation between exposures and readouts.
- Comparative peptide research: Included in side-by-side studies comparing GHRH analogs or related peptides for assay response differences (model-dependent).
- Analytical method development: Used in workflows that require characterization of GHRH analogs (e.g., mass-spectrometry–based identification approaches).
- Biomarker-focused assays: Incorporated into experiments tracking GH-axis–associated markers under controlled conditions (endpoint-dependent).
Handling and Storage Recommendations
- Store at -20°C and protect from light when not in use.
- Keep the container tightly sealed to reduce exposure to moisture and ambient contaminants.
- Minimize temperature cycling (repeated warm/cool changes) to help reduce degradation risk.
- Use standard laboratory PPE and follow your facility’s SOPs for peptide reagents.
- Dispose of materials properly in accordance with institutional and local regulatory requirements.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Hartvig RA, Holm NB, Dalsgaard PW, Reitzel LA, Müller IB, Linnet K. Identification of peptide and protein doping related drug compounds confiscated in Denmark between 2007-2013. Scandinavian Journal of Forensic Science. 2014;20(2):42-49. doi:10.2478/sjfs-2014-0003
- Knoop A, Thomas A, Fichant E, Delahaut P, Schänzer W, Thevis M. Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS. Anal Bioanal Chem. 2016;408(12):3145-3153. doi:10.1007/s00216-016-9377-3
- Memdouh S, Gavrilović I, Ng K, Cowan D, Abbate V. Advances in the detection of growth hormone-releasing hormone synthetic analogs. Drug Test Anal. 2021;13(11-12):1871-1887. doi:10.1002/dta.3183
- Thomas A, Walpurgis K, Thevis M. Chromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples. J Mass Spectrom. 2024;59(1):e4996. doi:10.1002/jms.4996
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