Semaglutide (20 mg)
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99% PURITY GUARANTEE
99% PURITY GUARANTEE
Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.
Preparation & Handling Notice
The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.
RESEARCH USE ONLY
This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.
Strength: 20 mg
CAS: 910463-68-2
Chemical Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular weight: 4113.6 g/mol
Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH
Synonyms: NN9535
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
Semaglutide is a synthetic GLP-1 receptor agonist analog supplied as a high-purity lyophilized peptide for laboratory research. It is widely studied in metabolic and endocrine research models to investigate glucose regulation, hormone signaling, and receptor-mediated cellular responses under controlled experimental conditions.
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INFORMATION
What is Semaglutide (20 mg)?
Semaglutide (20 mg) is a synthetic peptide commonly studied in metabolic and endocrine research. It is a modified analog of glucagon-like peptide-1 (GLP-1), involved in glucose signaling and metabolic regulation.
This peptide has specific structural modifications, including an amino acid change and the addition of a fatty acid side chain. These modifications enhance its stability and prolong its interaction with receptors in experimental systems, distinguishing it from native GLP-1, which is rapidly degraded in the body.
Semaglutide (20 mg) is ideal for extended research workflows, repeated assays, and large experimental series that require a steady supply of peptide material. This product is strictly for laboratory research use.
Product Specifications
- CAS Number: 910463-68-2
- Synonym: NN9535
- Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH
- Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
- Molecular Weight:6 g/mol
- Purity: ≥95% (verified by HPLC and mass spectrometry)
- Packaging Format: 20 mg lyophilized powder in sealed research-grade vial
- Storage Conditions: Store 2–8 °C (≤–20 °C long term). Protect from light.
- Intended Use: For Laboratory Research Use Only
Key Characteristics of Semaglutide (20 mg)
- Synthetic GLP-1 receptor agonist analog designed for controlled research
- Structural modifications improve resistance to rapid enzymatic breakdown in experimental models
- Fatty acid side-chain enhances receptor interaction duration in vitro
- High purity verified through HPLC and mass spectrometry
- Supplied as a lyophilized powder to maintain integrity before reconstitution
- Suitable for metabolic, endocrine, and receptor-signaling research
- Compatible with standard peptide preparation, dilution, and assay methods
How Semaglutide (20 mg) Supports Research
Semaglutide (20 mg) is widely used to study GLP-1 receptor-mediated signaling and related metabolic pathways. Researchers use this peptide to explore receptor activation, second-messenger cascades (e.g., cAMP production), and downstream effects on cellular metabolism in controlled laboratory and preclinical environments.
With its enhanced stability compared to native GLP-1, Semaglutide facilitates the investigation of prolonged receptor engagement and time-dependent signaling responses. It is particularly useful for studying receptor desensitization, sustained signaling pathway activation, and for comparative studies with other GLP-1 receptor agonists.
Research Applications & Usage Information
Semaglutide (20 mg) is typically used in laboratory research focused on:
- GLP-1 receptor binding and activation assays
- Incretin hormone signaling pathway studies
- Glucose metabolism and endocrine regulation
- Cellular signaling and second-messenger pathway analysis
- Comparative studies of short-acting vs. long-acting GLP-1 analogs
- Preclinical metabolic model research
All applications are investigational and limited to controlled laboratory settings.
Handling and Storage Recommendations
- Store at 2–8 °C (≤–20 °C for long-term storage). Protect from light.
- Keep vials tightly sealed when not in use.
- Minimize exposure to moisture and direct light during handling.
- Allow vials to equilibrate before opening to prevent condensation.
- After reconstitution, store solutions at 2–8 °C according to laboratory protocols.
- Avoid repeated freeze-thaw cycles to support research applications.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Lau J, Bloch P, Schäffer L, et al. Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. J Med Chem. 2015;58(18):7370-7380. doi:10.1021/acs.jmedchem.5b00726
- Loomba R, Abdelmalek MF, Armstrong MJ, et al. Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial. Lancet Gastroenterol Hepatol. 2023;8(6):511-522. doi:10.1016/S2468-1253(23)00068-7
- Knudsen LB, Lau J. The Discovery and Development of Liraglutide and Semaglutide. Front Endocrinol (Lausanne). 2019;10:155. Published 2019 Apr 12. doi:10.3389/fendo.2019.00155
What is Semaglutide (20 mg)?
Semaglutide (20 mg) is a synthetic peptide commonly studied in metabolic and endocrine research. It is a modified analog of glucagon-like peptide-1 (GLP-1), involved in glucose signaling and metabolic regulation.
This peptide has specific structural modifications, including an amino acid change and the addition of a fatty acid side chain. These modifications enhance its stability and prolong its interaction with receptors in experimental systems, distinguishing it from native GLP-1, which is rapidly degraded in the body.
Semaglutide (20 mg) is ideal for extended research workflows, repeated assays, and large experimental series that require a steady supply of peptide material. This product is strictly for laboratory research use.
Product Specifications
- CAS Number: 910463-68-2
- Synonym: NN9535
- Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH
- Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
- Molecular Weight:6 g/mol
- Purity: ≥95% (verified by HPLC and mass spectrometry)
- Packaging Format: 20 mg lyophilized powder in sealed research-grade vial
- Storage Conditions: Store 2–8 °C (≤–20 °C long term). Protect from light.
- Intended Use: For Laboratory Research Use Only
Key Characteristics of Semaglutide (20 mg)
- Synthetic GLP-1 receptor agonist analog designed for controlled research
- Structural modifications improve resistance to rapid enzymatic breakdown in experimental models
- Fatty acid side-chain enhances receptor interaction duration in vitro
- High purity verified through HPLC and mass spectrometry
- Supplied as a lyophilized powder to maintain integrity before reconstitution
- Suitable for metabolic, endocrine, and receptor-signaling research
- Compatible with standard peptide preparation, dilution, and assay methods
How Semaglutide (20 mg) Supports Research
Semaglutide (20 mg) is widely used to study GLP-1 receptor-mediated signaling and related metabolic pathways. Researchers use this peptide to explore receptor activation, second-messenger cascades (e.g., cAMP production), and downstream effects on cellular metabolism in controlled laboratory and preclinical environments.
With its enhanced stability compared to native GLP-1, Semaglutide facilitates the investigation of prolonged receptor engagement and time-dependent signaling responses. It is particularly useful for studying receptor desensitization, sustained signaling pathway activation, and for comparative studies with other GLP-1 receptor agonists.
Research Applications & Usage Information
Semaglutide (20 mg) is typically used in laboratory research focused on:
- GLP-1 receptor binding and activation assays
- Incretin hormone signaling pathway studies
- Glucose metabolism and endocrine regulation
- Cellular signaling and second-messenger pathway analysis
- Comparative studies of short-acting vs. long-acting GLP-1 analogs
- Preclinical metabolic model research
All applications are investigational and limited to controlled laboratory settings.
Handling and Storage Recommendations
- Store at 2–8 °C (≤–20 °C for long-term storage). Protect from light.
- Keep vials tightly sealed when not in use.
- Minimize exposure to moisture and direct light during handling.
- Allow vials to equilibrate before opening to prevent condensation.
- After reconstitution, store solutions at 2–8 °C according to laboratory protocols.
- Avoid repeated freeze-thaw cycles to support research applications.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Lau J, Bloch P, Schäffer L, et al. Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. J Med Chem. 2015;58(18):7370-7380. doi:10.1021/acs.jmedchem.5b00726
- Loomba R, Abdelmalek MF, Armstrong MJ, et al. Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial. Lancet Gastroenterol Hepatol. 2023;8(6):511-522. doi:10.1016/S2468-1253(23)00068-7
- Knudsen LB, Lau J. The Discovery and Development of Liraglutide and Semaglutide. Front Endocrinol (Lausanne). 2019;10:155. Published 2019 Apr 12. doi:10.3389/fendo.2019.00155
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