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NOVERA COMPOUNDS

Kisspeptin (5mg)

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99% PURITY GUARANTEE

Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.

Preparation & Handling Notice

The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.

RESEARCH USE ONLY

This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.

Strength: 5 mg
CAS: 374675-21-5
Chemical Formula: C₆₃H₈₃N₁₇O₁₄
Molecular weight: 1302.4 g/mol
Peptide Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
Synonyms: Metastin (45–54), KP-10
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.

Kisspeptin is a regulatory peptide studied in reproductive and endocrine research. It plays a central role in signaling pathways that influence gonadotropin releasing hormone (GnRH) activity. In laboratory settings, kisspeptin is used to investigate hypothalamic signaling, hormonal feedback mechanisms, and KISS1R (GPR54) receptor interactions involved in reproductive axis control.

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INFORMATION

What is Kisspeptin (5mg)?

Kisspeptin is a regulatory peptide studied within endocrine and neuroendocrine research, specifically in the subcategory of reproductive axis signaling. It is widely studied for its interaction with the KISS1 receptor (KISS1R), also known as GPR54.

In laboratory research, kisspeptin is used to investigate the signaling pathways involved in regulating gonadotropin-releasing hormone (GnRH). Its defined amino acid sequence allows researchers to examine receptor activation, hormonal feedback mechanisms, and neuroendocrine communication within controlled experimental systems.

This product is intended solely for laboratory research use.

Product Specifications

  • CAS Number: 374675-21-5
  • Peptide Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
  • Chemical Formula: C₆₃H₈₃N₁₇O₁₄
  • Molecular weight: 1302.4 g/mol
  • Synonyms: Metastin (45–54), KP-10
  • Purity: ≥99%
  • Packaging Format: 5mg lyophilized vial
  • Storage Conditions: Store at -20°C, avoid light exposure
  • Designation: For Laboratory Research Use Only

Key Characteristics of Kisspeptin (5mg)

  • Synthetic peptide with a defined and reproducible molecular structure.
  • High purity (≥99%), suitable for controlled laboratory experiments.
  • Studied for its interaction with the KISS1R (GPR54) receptor.
  • Commonly examined in reproductive and neuroendocrine signaling research.
  • Supplied in lyophilized format for laboratory flexibility.
  • Requires low-temperature storage to preserve structural stability.
  • Not approved for diagnostic, therapeutic, or clinical use.

How Kisspeptin (5mg) Supports Research

Kisspeptin is widely used in laboratory settings to study signaling pathways that regulate the reproductive endocrine axis. By interacting with the KISS1 receptor in experimental models, kisspeptin helps researchers evaluate GnRH pathway activation, hormone signaling coordination, and feedback regulation mechanisms.

Its consistent structure supports reproducible experimental design in neuroendocrine research.

Research Applications & Usage Information

Kisspeptin (5mg) is commonly used in laboratory research for:

  • GnRH pathway activation studies.
  • Reproductive endocrine axis modeling.
  • KISS1 receptor binding and activation assays.
  • Hormonal feedback loop investigations.
  • Neuroendocrine communication research.
  • Comparative studies with other reproductive signaling peptides.
  • In vitro cell-based receptor signaling experiments.

This peptide is supplied exclusively for laboratory research and must be used in accordance with institutional safety and compliance standards.

Handling and Storage Recommendations

  • Store at −20°C immediately upon receipt.
  • Protect from direct light exposure.
  • Keep the vial tightly sealed when not in use.
  • Avoid repeated freeze-thaw cycles.
  • Handle using appropriate laboratory protective equipment.
  • Follow standard laboratory documentation and handling procedures.

Proper storage and careful handling help maintain peptide integrity and support consistent research outcomes.

Research Use Only Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

  1. Kotani M, Detheux M, Vandenbogaerde A, et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem. 2001;276(37):34631-34636. doi:10.1074/jbc.M104847200
  2. Oakley AE, Clifton DK, Steiner RA. Kisspeptin signaling in the brain. Endocr Rev. 2009;30(6):713-743. doi:10.1210/er.2009-0005
  3. Sliwowska JH, Woods NE, Alzahrani AR, Paspali E, Tate RJ, Ferro VA. Kisspeptin a potential therapeutic target in treatment of both metabolic and reproductive dysfunction. J Diabetes. 2024;16(4):e13541. doi:10.1111/1753-0407.13541
  4. Mills EGA, Dhillo WS, Comninos AN. Kisspeptin and the control of emotions, mood and reproductive behaviour. Journal of Endocrinology. 2018;239(1):R1-R12. doi:10.1530/joe-18-0269

What is Kisspeptin (5mg)?

Kisspeptin is a regulatory peptide studied within endocrine and neuroendocrine research, specifically in the subcategory of reproductive axis signaling. It is widely studied for its interaction with the KISS1 receptor (KISS1R), also known as GPR54.

In laboratory research, kisspeptin is used to investigate the signaling pathways involved in regulating gonadotropin-releasing hormone (GnRH). Its defined amino acid sequence allows researchers to examine receptor activation, hormonal feedback mechanisms, and neuroendocrine communication within controlled experimental systems.

This product is intended solely for laboratory research use.

Product Specifications

  • CAS Number: 374675-21-5
  • Peptide Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
  • Chemical Formula: C₆₃H₈₃N₁₇O₁₄
  • Molecular weight: 1302.4 g/mol
  • Synonyms: Metastin (45–54), KP-10
  • Purity: ≥99%
  • Packaging Format: 5mg lyophilized vial
  • Storage Conditions: Store at -20°C, avoid light exposure
  • Designation: For Laboratory Research Use Only

Key Characteristics of Kisspeptin (5mg)

  • Synthetic peptide with a defined and reproducible molecular structure.
  • High purity (≥99%), suitable for controlled laboratory experiments.
  • Studied for its interaction with the KISS1R (GPR54) receptor.
  • Commonly examined in reproductive and neuroendocrine signaling research.
  • Supplied in lyophilized format for laboratory flexibility.
  • Requires low-temperature storage to preserve structural stability.
  • Not approved for diagnostic, therapeutic, or clinical use.

How Kisspeptin (5mg) Supports Research

Kisspeptin is widely used in laboratory settings to study signaling pathways that regulate the reproductive endocrine axis. By interacting with the KISS1 receptor in experimental models, kisspeptin helps researchers evaluate GnRH pathway activation, hormone signaling coordination, and feedback regulation mechanisms.

Its consistent structure supports reproducible experimental design in neuroendocrine research.

Research Applications & Usage Information

Kisspeptin (5mg) is commonly used in laboratory research for:

  • GnRH pathway activation studies.
  • Reproductive endocrine axis modeling.
  • KISS1 receptor binding and activation assays.
  • Hormonal feedback loop investigations.
  • Neuroendocrine communication research.
  • Comparative studies with other reproductive signaling peptides.
  • In vitro cell-based receptor signaling experiments.

This peptide is supplied exclusively for laboratory research and must be used in accordance with institutional safety and compliance standards.

Handling and Storage Recommendations

  • Store at −20°C immediately upon receipt.
  • Protect from direct light exposure.
  • Keep the vial tightly sealed when not in use.
  • Avoid repeated freeze-thaw cycles.
  • Handle using appropriate laboratory protective equipment.
  • Follow standard laboratory documentation and handling procedures.

Proper storage and careful handling help maintain peptide integrity and support consistent research outcomes.

Research Use Only Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

  1. Kotani M, Detheux M, Vandenbogaerde A, et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem. 2001;276(37):34631-34636. doi:10.1074/jbc.M104847200
  2. Oakley AE, Clifton DK, Steiner RA. Kisspeptin signaling in the brain. Endocr Rev. 2009;30(6):713-743. doi:10.1210/er.2009-0005
  3. Sliwowska JH, Woods NE, Alzahrani AR, Paspali E, Tate RJ, Ferro VA. Kisspeptin a potential therapeutic target in treatment of both metabolic and reproductive dysfunction. J Diabetes. 2024;16(4):e13541. doi:10.1111/1753-0407.13541
  4. Mills EGA, Dhillo WS, Comninos AN. Kisspeptin and the control of emotions, mood and reproductive behaviour. Journal of Endocrinology. 2018;239(1):R1-R12. doi:10.1530/joe-18-0269
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