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Quantity Our Price
1 - 5 pack(s) $49.00 USD
6 - 10 pack(s) $46.00 USD
11 - 20 pack(s) $44.00 USD
21+ pack(s) USD$43.00 43.00USD
Manufacturer: Croma
Active Substance(s) : Hyaluronic acid
Strength: 23mg/ml
Pack Size: 1-1ml prefilled syringe
Other Known Names: PRINCESS® FILLER
Accessories: Package insert, 2-27G 1/2 needles, 2 traceability labels

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Product Information

What is Saypha Filler?

Saypha Filler is a sterile, biodegradable, viscoelastic, clear, transparent, isotonic, and homogenized cosmetic filler. Saypha Filler consists of cross-linked hyaluronic acid (HA) that is obtained from Streptococcus equi bacteria and formulated to a concentration of 23mg/ml in a physiologic buffer. Backed by the hydrating power of hyaluronic acid, this unique product reduces the look of wrinkles and creases.

Accessories or items included

  • One syringe of Saypha Filler
  • Two 27G ½” disposable, sterile needles
  • Package insert
  • Two traceability labels

What are the benefits of this product?

Saypha Filler is a versatile cosmetic filler that effectively corrects facial wrinkles and increases lip volume. This product allows a patient to achieve desirable, long-lasting effects in a pain-free manner.

How does this product work?

Saypha Filler is made of hyaluronic acid. The hyaluronic acid in Saypha Filler is cross-linked using patented Supreme Monophasic and Reticulated Technology (S.M.A.R.T.), which produces a dense three-dimensional structure that is resistant to degradation. This enables the filler to provide longer-lasting, more durable results.
Aging and environmental damage can cause the skin's natural hyaluronic acid to break down, causing the loss of moisture and volume in the skin. This can produce wrinkles and enhance facial lines. When Saypha Filler is injected into the mid-to-deep dermis, the skin's supply of hyaluronic acid is replenished, which adds enough volume to reduce the look of lines and wrinkles. The result is smoother and more youthful-looking skin.

What are the ingredients?

  • Cross-linked sodium hyaluronate (23mg/ml)
  • Sodium chloride
  • pH 6.8–7.6 phosphate buffer

Use Instructions

How to inject/administer this product

This product is administered via injection into the mid-to-deep dermis with a 27G ½” needle. The injection must be performed by an authorized, trained medical professional only. It should be injected slowly into disinfected, non-inflamed, and healthy skin using appropriate injection techniques. Following the procedure, massage the treated area gently to ensure the uniform distribution of the product.

When should I use this product?

Saypha Filler should be used to treat moderate to severe facial wrinkles and to add volume to shallow areas of the face. Treatment consists of a single session, and yearly top-up treatments can be done to maintain the initial results.

What areas can I treat with this product?

This filler can be used on forehead furrows, the temple, the cheeks, perioral wrinkles, marionette lines, the nasolabial folds, the lips, and the chin.

How long do results last?

When you inject Saypha Filler into your patient's dermis, the hyaluronic acid immediately binds to moisture within the skin, instantly smoothing the look of wrinkles and creases. The hyaluronic acid resists breaking down for a few months, during which time it stimulates the production of collagen and elastin to improve the skin's structure and elasticity. Patients can enjoy the results of their Saypha Filler injection for about six to 10 months before deciding whether to return for another treatment.

Frequently Asked Questions

Who is an ideal candidate for this product?

If your patients are experiencing certain signs of aging, such as the formation of moderate to severe wrinkles and the enhancement of facial creases, Saypha Filler can help. You can use Saypha Filler to reduce the appearance of glabellar lines on the forehead, marionette lines between the mouth and chin, perioral wrinkles around the mouth, and nasolabial folds between the nose and the mouth. Additionally, it may be used to replace or create volume in the lips.

Why should I purchase this product?

Saypha Filler uses purified hyaluronic acid to restore volume to the skin and reduce the look of wrinkles and creases. Since this form of hyaluronic acid is found naturally within the skin and does not come from animal sources, it is a safe and effective wrinkle treatment with few side effects. Order wholesale Saypha Filler from Medica Depot today to help your patients turn back the clock on their facial skin.

What are the most common side effects?

The hyaluronic acid in Saypha Filler is highly purified for safety. Moreover, since it does not originate from animals, no allergy test is needed before a Saypha Filler treatment. However, there are some common side effects associated with the use of Saypha; these include mild swelling, tenderness, bruising, and redness at the injection site. However, these issues usually resolve themselves within hours of the injection. Other side effects can include light bleeding from the injection; mild edemas or erythema, which can cause itchiness, pain, and pressure; and the formation of small hematomas, indurations, or lumps in the treatment area. Any adverse effects should be reported to the manufacturer.

*This website offers only genuine products made by their original manufacturer. All brands are trademarks of their respective owners. This website is not operated by, supported by, or affiliated with the manufacturer in any way. Product packaging may not be exactly as shown.

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