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Brand: SAYPHA®


Quantity Price
1 - 5 $49.00
6 - 10 $46.00
11 - 20 $44.00
21+ $43.00

Manufacturer: Croma
Active Substance(s): HYALURONIC ACID
Strength: 23mg/ml
Pack Size: 1 x 1 ml Pre-Filled Syringe, 2 x 27G ½” Needles

Saypha® Filler is a universal product and appropriate for different aesthetic treatments such as correcting moderate facial wrinkles and lines as well as enhanceing lip volume. The product can be used for all areas of the face, specifically for perioral wrinkles, lip contour and increase lip volume. Used to treat moderate to severe facial wrinkles and to add volume to shallow areas of the face.


Frequently Asked Questions

Saypha Filler is a sterile, biodegradable, viscoelastic, clear, transparent, isotonic, and homogenized cosmetic filler. Saypha consists of cross-linked hyaluronic acid (HA) that is obtained from Streptococcus equi bacteria and formulated to a concentration of 23mg/ml in a physiologic buffer. Backed by the hydrating power of HA, this unique formulation reduces the look of wrinkles and creases. Also, it can be used in combination with Lidocaine for ease of application.

One syringe of Saypha Filler
Two 27G ½” disposable, sterile needles
Package insert
Two traceability labels

Saypha is a versatile cosmetic filler that effectively corrects facial wrinkles and increases lip volume. This dermal product allows a patient to achieve desirable, long-lasting effects in a pain-free manner when applied with the addition of Lidocaine.

Saypha Filler is made of hyaluronic acid(HA). The HA in Saypha  is cross-linked using patented Supreme Monophasic and Reticulated Technology (S.M.A.R.T.), which produces a dense three-dimensional structure that is resistant to degradation. This enables the filler to provide longer-lasting, more durable results.
Aging and environmental damage can cause the skin’s natural HA to break down, causing the loss of moisture and volume in the skin. This can produce wrinkles and enhance the appearance of lines. When Saypha is injected into the mid-to-deep dermis, the skin’s supply of HA is replenished, which adds enough volume to reduce the look of lines and wrinkles. The result is smoother and more youthful-looking skin.

Cross-linked sodium hyaluronate (23mg/ml)
Sodium chloride
pH 6.8–7.6 phosphate buffer

This product is administered via injection into the mid-to-deep dermis with a 27G ½” needle. The injection must be performed by an authorized, trained medical professional only. It should be injected slowly into disinfected, non-inflamed, and healthy skin using appropriate injection techniques. Following the procedure, massage the treated area gently to ensure the uniform distribution of the product.

Saypha Filler should be used to treat moderate to severe wrinkles and to introduce volume to shallow areas of the face. Treatment consists of a single session, and yearly top-up treatments can be done to maintain the initial results.

This filler can be used on forehead furrows, the temple, the cheeks, perioral wrinkles, marionette lines, the nasolabial folds, the mouth area, and the chin.

When you inject Saypha Filler into your patient’s dermis, the hyaluronic acid immediately binds to moisture within the skin, instantly smoothing the look of lines and creases. The hyaluronic acid resists breaking down for a few months, during which time it stimulates the production of collagen and elastin to improve the skin’s structure and elasticity. Patients can enjoy the results of their Saypha injection for about six to 10 months before deciding whether to return for another treatment.

If your patients are experiencing certain signs of aging, such as the formation of moderate to severe lines and the enhancement of appearance of creases, Saypha Filler can help. You can use Saypha to reduce the appearance of glabellar lines on the forehead, marionette lines between the mouth and chin, perioral wrinkles around the mouth, and nasolabial folds between the nose and the mouth. Additionally, it may be used to replace or create volume in the lips.

Saypha uses purified hyaluronic acid to restore volume to the skin and reduce the look of lines and creases. Since this form of hyaluronic acid is found naturally within the skin and does not come from animal sources, it is a safe and effective wrinkle treatment with few side effects. Order wholesale Saypha Filler from Medica Depot today to help your patients turn back the clock on their facial skin.

The hyaluronic acid in Saypha is highly purified for safety. Moreover, since it does not originate from animals, no allergy test is needed before a Saypha treatment. However, there are some common side effects associated with the use of Saypha; these include mild swelling, tenderness, bruising, and redness at the injection site. However, these issues usually resolve themselves within hours of the injection. Other side effects can include light bleeding from the injection; mild edemas or erythema, which can cause itchiness, pain, and pressure; and the formation of small hematomas, indurations, or lumps in the treatment area. Any adverse effects should be reported to the manufacturer.

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