GHRP-2 5mg

What is GHRP-2 (5mg)?

GHRP-2 (5 mg), also known as Pralmorelin, is a synthetic hexapeptide classified as a muscle growth and performance peptide. It is primarily used in laboratory and preclinical research settings as a growth hormone secretagogue to study peptide-mediated endocrine signaling under controlled experimental conditions.

GHRP-2 is structurally designed to interact with the growth hormone secretagogue receptor (GHSR-1a), a receptor associated with ghrelin-related signaling pathways. Due to this interaction, researchers use GHRP-2 to investigate growth hormone release patterns, receptor activation dynamics, and downstream intracellular signaling cascades in both in vitro and animal model studies. The 5 mg presentation is ideal for small-scale, controlled experimental workflows requiring precise handling and reproducibility.

This product is strictly for laboratory research use and is not approved for human or veterinary applications.

Product Specifications

• CAS Number: 158861-67-7
• Peptide Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
• Molecular Formula: C₄₅H₅₅N₉O₆
• Molecular weight: 817.97 g/mol
• Synonyms: GHRP-2, Pralmorelin, Growth Hormone Releasing Peptide-2
• Purity: ≥95% (typically verified by HPLC and mass spectrometry)
• Packaging Format: 5 mg lyophilized powder in sealed research vial
• Storage Conditions: Store at −20 °C; protect from light and moisture
• Intended Use: For Laboratory Research Use Only

Key Characteristics of GHRP-2 (5mg)

• Synthetic hexapeptide designed for receptor-specific research
• Frequently used in endocrine and metabolic signaling studies
• Lyophilized format ensures stability and extended shelf life
• Analytical verification typically performed using HPLC and mass spectrometry
• Compatible with standard peptide handling and storage protocols
• Designed for controlled in vitro and preclinical research applications

How GHRP-2 (5mg) Supports Research

GHRP-2 (5 mg) is commonly used in laboratory studies to explore growth hormone–related signaling and ghrelin-associated receptor pathways. Researchers investigate how this peptide interacts with GHSR-1a receptors and influences intracellular signaling mechanisms, such as calcium mobilization and second-messenger pathways.

Due to its short-chain peptide structure and defined characteristics, GHRP-2 is often used in controlled experiments that investigate endocrine communication, receptor binding kinetics, and peptide stability in experimental systems. The 5 mg format is particularly suited for small-batch experimental designs and comparative peptide research.

Research Applications & Usage Information

GHRP-2 (5 mg) is commonly used in laboratory and preclinical research involving:

• Growth hormone secretagogue receptor (GHSR-1a) signaling studies
• Endocrine pathway modeling in vitro and in animal systems
• Peptide–receptor binding and activation assays
• Intracellular signaling and calcium-response investigations
• Comparative analysis of growth hormone–releasing peptides
• Metabolic regulation and energy-balance research frameworks

All applications are limited to controlled research environments and are investigational in nature.

Handling and Storage Recommendations

To preserve structural integrity and maintain research reliability:

• Store unopened vials at −20 °C in a dry, light-protected environment
• Avoid exposure to heat, humidity, and direct sunlight
• Allow the vial to equilibrate to room temperature before opening to prevent condensation
• After reconstitution, store solutions at 2–8 °C and use within laboratory-defined timeframes
• Avoid repeated freeze–thaw cycles to minimize degradation

Proper handling supports stability, reproducibility, and experimental reliability.

Research Use Only Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

1. Laferrère B, Abraham C, Russell CD, Bowers CY. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab. 2005;90(2):611-614. doi:10.1210/jc.2004-1719
2. Laferrère B, Hart AB, Bowers CY. Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake. Obesity (Silver Spring). 2006;14(6):1056-1063. doi:10.1038/oby.2006.121
3. National Center for Biotechnology Information. PubChem Compound Summary for CID 6918245, Pralmorelin. https://pubchem.ncbi.nlm.nih.gov/compound/Pralmorelin.
4. Yin Y, Li Y, Zhang W. The growth hormone secretagogue receptor: its intracellular signaling and regulation. Int J Mol Sci. 2014;15(3):4837-4855. Published 2014 Mar 19. doi:10.3390/ijms15034837