Bronchogen (50mg)
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99% PURITY GUARANTEE
99% PURITY GUARANTEE
Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.
Preparation & Handling Notice
The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.
RESEARCH USE ONLY
This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.
Strength: 50 mg
CAS: N/A
Chemical Formula: C₁₈H₃₀N₄O₉
Molecular weight: 446.45 g/mol
Peptide Sequence: Ala-Glu-Asp-Leu (AEDL)
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
Bronchogen is a short synthetic tetrapeptide (AEDL) classified as an organ specific bioregulatory peptide. In laboratory research, it is used to explore gene expression patterns and nucleic acid interaction endpoints in bronchial/respiratory epithelium model systems and is supplied at high purity for reproducible experimental workflows, for laboratory research use only.
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Novera Research delivers high-quality research peptides developed under strict manufacturing and quality-control standards. Each product is carefully synthesized, tested, and handled to ensure consistency, reliability, and transparency for advanced research applications.
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- Analytical testing to verify quality and composition
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- Stored and shipped under controlled conditions
High-purity, research-grade peptide synthesis
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INFORMATION
What is Bronchogen (50mg)?
Bronchogen (50mg) is a short synthetic tetrapeptide positioned within the organ-specific & bioregulator peptide space, where it is most often referenced in respiratory/bronchial epithelium–focused research contexts.
In laboratory settings, it may be used as a controlled test article in cell-based models to explore how small peptides interact with nuclear regulatory processes, such as DNA/chromatin-associated regulation, and how those interactions may correlate with shifts in gene-expression patterns under defined experimental conditions.
Product Specifications
- Category: Peptides
- Subcategory: Organ-Specific & Bioregulator Peptides
- Peptide Sequence: Ala–Glu–Asp–Leu (AEDL)
- Chemical Formula: C₁₈H₃₀N₄O₉
- Molecular Weight: 446.45 g/mol
- Purity: ≥99% purity (HPLC verified)
- Packaging Format: 50 mg
- Storage Conditions: Store at -20°C, avoid light exposure
- For Laboratory Research Use Only
Key Characteristics of Bronchogen (50mg)
- Defined, short peptide format (tetrapeptide): Useful for controlled studies in which small, sequence-specific peptides are evaluated in model systems.
- High stated purity (≥99%, HPLC verified): Supports repeatability when comparing results across assays and batches.
- Reported research focus: Explored in cell culture and other preclinical contexts related to bronchial epithelium biology and regulatory signaling.
- Studied for nucleic-acid interaction: Experimental work has reported effects consistent with DNA interaction/thermostability changes in model systems.
How Bronchogen (50mg) Supports Research
Bronchogen is used as a research reagent to help investigators explore how short peptides may influence cell behavior and gene activity under controlled conditions. Published work has described bronchogen/ADEL being studied in human bronchial epithelial cell cultures, including associations with markers of cell proliferation and epithelial differentiation (gene-expression level observations in experimental models).
Separately, experimental measurements have reported peptide-associated changes in DNA melting/thermostability in vitro, supporting ongoing interest in how short peptides can interact with nucleic acids in research systems.
Research Applications & Usage Information
Bronchogen (50mg) is generally used in laboratory research, such as:
- Bronchial epithelium differentiation models: Studies evaluating changes in gene-expression markers associated with bronchial epithelial identity and maturation (cell culture research).
- Cell proliferation and aging-passage comparisons: Research examining how biomarkers differ across “younger” vs “older” cell culture passages in bronchial epithelium systems.
- Gene-expression and transcription program studies: Broader “short peptide” research investigating how small peptides may affect transcriptional regulation in tissue-biased cell models.
- DNA/chromatin interaction assays: In vitro research exploring peptide binding to DNA and related biophysical readouts (e.g., melting temperature shifts).
- Method development/comparative peptide panels: Use as one component in short-peptide screening panels, where multiple sequences are compared under the same assay conditions.
Note: All above describe research contexts reported in preclinical or in-vitro literature; they are not validated clinical outcomes.
Handling and Storage Recommendations
- Store at -20°C and protect from light to help maintain peptide integrity.
- Keep the container tightly closed when not in use to limit moisture exposure.
- Avoid unnecessary temperature cycling (repeated warming/cooling), which can increase the risk of degradation for many synthetic peptides.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Monaselidze JR, Khavinson VKh, Gorgoshidze MZ, et al. Effect of the peptide bronchogen (Ala-Asp-Glu-Leu) on DNA thermostability. Bull Exp Biol Med. 2011;150(3):375-377. doi:10.1007/s10517-011-1146-x
- Khavinson VKh, Tendler SM, Vanyushin BF, et al. Peptide regulation of gene expression and protein synthesis in bronchial epithelium. Lung. 2014;192(5):781-791. doi:10.1007/s00408-014-9620-7
- Ashapkin VV, Linkova NS, Khavinson VKh, Vanyushin BF. Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. Biochemistry (Mosc). 2015;80(3):310-322. doi:10.1134/S0006297915030062
- Khavinson VK, Popovich IG, Linkova NS, Mironova ES, Ilina AR. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053. Published 2021 Nov 22. doi:10.3390/molecules26227053
- Khavinson V, Linkova N, Dyatlova A, Kuznik B, Umnov R. Peptides: Prospects for Use in the Treatment of COVID-19. Molecules. 2020;25(19):4389. Published 2020 Sep 24. doi:10.3390/molecules25194389
What is Bronchogen (50mg)?
Bronchogen (50mg) is a short synthetic tetrapeptide positioned within the organ-specific & bioregulator peptide space, where it is most often referenced in respiratory/bronchial epithelium–focused research contexts.
In laboratory settings, it may be used as a controlled test article in cell-based models to explore how small peptides interact with nuclear regulatory processes, such as DNA/chromatin-associated regulation, and how those interactions may correlate with shifts in gene-expression patterns under defined experimental conditions.
Product Specifications
- Category: Peptides
- Subcategory: Organ-Specific & Bioregulator Peptides
- Peptide Sequence: Ala–Glu–Asp–Leu (AEDL)
- Chemical Formula: C₁₈H₃₀N₄O₉
- Molecular Weight: 446.45 g/mol
- Purity: ≥99% purity (HPLC verified)
- Packaging Format: 50 mg
- Storage Conditions: Store at -20°C, avoid light exposure
- For Laboratory Research Use Only
Key Characteristics of Bronchogen (50mg)
- Defined, short peptide format (tetrapeptide): Useful for controlled studies in which small, sequence-specific peptides are evaluated in model systems.
- High stated purity (≥99%, HPLC verified): Supports repeatability when comparing results across assays and batches.
- Reported research focus: Explored in cell culture and other preclinical contexts related to bronchial epithelium biology and regulatory signaling.
- Studied for nucleic-acid interaction: Experimental work has reported effects consistent with DNA interaction/thermostability changes in model systems.
How Bronchogen (50mg) Supports Research
Bronchogen is used as a research reagent to help investigators explore how short peptides may influence cell behavior and gene activity under controlled conditions. Published work has described bronchogen/ADEL being studied in human bronchial epithelial cell cultures, including associations with markers of cell proliferation and epithelial differentiation (gene-expression level observations in experimental models).
Separately, experimental measurements have reported peptide-associated changes in DNA melting/thermostability in vitro, supporting ongoing interest in how short peptides can interact with nucleic acids in research systems.
Research Applications & Usage Information
Bronchogen (50mg) is generally used in laboratory research, such as:
- Bronchial epithelium differentiation models: Studies evaluating changes in gene-expression markers associated with bronchial epithelial identity and maturation (cell culture research).
- Cell proliferation and aging-passage comparisons: Research examining how biomarkers differ across “younger” vs “older” cell culture passages in bronchial epithelium systems.
- Gene-expression and transcription program studies: Broader “short peptide” research investigating how small peptides may affect transcriptional regulation in tissue-biased cell models.
- DNA/chromatin interaction assays: In vitro research exploring peptide binding to DNA and related biophysical readouts (e.g., melting temperature shifts).
- Method development/comparative peptide panels: Use as one component in short-peptide screening panels, where multiple sequences are compared under the same assay conditions.
Note: All above describe research contexts reported in preclinical or in-vitro literature; they are not validated clinical outcomes.
Handling and Storage Recommendations
- Store at -20°C and protect from light to help maintain peptide integrity.
- Keep the container tightly closed when not in use to limit moisture exposure.
- Avoid unnecessary temperature cycling (repeated warming/cooling), which can increase the risk of degradation for many synthetic peptides.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Monaselidze JR, Khavinson VKh, Gorgoshidze MZ, et al. Effect of the peptide bronchogen (Ala-Asp-Glu-Leu) on DNA thermostability. Bull Exp Biol Med. 2011;150(3):375-377. doi:10.1007/s10517-011-1146-x
- Khavinson VKh, Tendler SM, Vanyushin BF, et al. Peptide regulation of gene expression and protein synthesis in bronchial epithelium. Lung. 2014;192(5):781-791. doi:10.1007/s00408-014-9620-7
- Ashapkin VV, Linkova NS, Khavinson VKh, Vanyushin BF. Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. Biochemistry (Mosc). 2015;80(3):310-322. doi:10.1134/S0006297915030062
- Khavinson VK, Popovich IG, Linkova NS, Mironova ES, Ilina AR. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053. Published 2021 Nov 22. doi:10.3390/molecules26227053
- Khavinson V, Linkova N, Dyatlova A, Kuznik B, Umnov R. Peptides: Prospects for Use in the Treatment of COVID-19. Molecules. 2020;25(19):4389. Published 2020 Sep 24. doi:10.3390/molecules25194389
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