TRH Thyrotropin (20mg)
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99% PURITY GUARANTEE
99% PURITY GUARANTEE
Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.
Preparation & Handling Notice
The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.
RESEARCH USE ONLY
This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.
Strength: 20 mg
CAS: 24305-27-9
Chemical Formula: C₁₆H₂₂N₆O₄
Molecular weight: 362.38 g/mol
Peptide Sequence: Pyr-His-Pro-NH2
Synonyms: Protirelin
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
TRH (thyrotropin-releasing hormone), a tripeptide neuroendocrine tool, supports laboratory research on TRH receptor activity, hypothalamic–pituitary–thyroid axis signaling, and endocrine pathways. Used in receptor pharmacology, dose-response assays, and pathway-mapping in controlled models. For laboratory research use only.
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INFORMATION
What is TRH (Thyrotropin-Releasing Hormone) (20 mg)?
TRH (thyrotropin-releasing hormone) is a short, naturally occurring peptide commonly used in laboratory research to study neuroendocrine signaling and hormone-regulation pathways. It is often grouped with brain, cognitive, and nootropic peptides, as it serves as a tool compound in studies of hypothalamic–pituitary signaling, receptor activity, and neurotransmitter-linked endocrine responses. Its small size and well-characterized structure make it suitable for controlled experimental models.
Product Specifications
- CAS Number: 24305-27-9
- Peptide Sequence: Pyr-His-Pro-NH₂
- Category: Peptide
- Subcategory: Brain, Cognitive & Nootropic Peptides
- Molecular Weight:38 g/mol
- Molecular Formula: C₁₆H₂₂N₆O₄
- Synonyms: Protirelin
- Purity: ≥99%
- Packaging Format: 20 mg
- Storage Conditions: Store at -20°C; avoid light exposure
- Compliance Notice: For laboratory research use only
Key Characteristics of TRH (Thyrotropin-Releasing Hormone) (20 mg)
- Research-Grade Peptide Tool: Used in controlled neuroendocrine study designs.
- High Purity (≥99%): Supports reproducibility across experiments.
- Well-Defined Tripeptide Structure: Suitable for receptor and pathway research.
- Neuroendocrine Relevance: Common in hypothalamic–pituitary axis studies.
- Storage: Store at -20°C; avoid exposure to light.
How TRH (Thyrotropin-Releasing Hormone) (20 mg) Supports Research
In laboratory settings, TRH is used to investigate TRH receptor activity and signaling pathways involved in endocrine regulation. It supports studies exploring pituitary hormone-release pathways, neuroendocrine communication, and how peptide signals influence downstream cellular behavior in controlled in vitro or in vivo research models.
Research Applications & Usage Information
TRH (20 mg) is commonly used in laboratory research for:
- TRH Receptor Research: Evaluating receptor interaction and signaling responses.
- Neuroendocrine Pathway Studies: Supporting hypothalamic–pituitary axis research.
- Hormone Signaling Models: Used in studies of regulated hormone release.
- Cell Signaling Assays: Mapping downstream pathway activation patterns.
- Method Development: Useful as a reference peptide in assay validation.
- Comparative Research: Included in studies comparing peptide signaling profiles.
Handling and Storage Recommendations
- Store at -20°C; avoid light exposure.
- Minimize time at room temperature. Make sure to reduce exposure during handling.
- Keep vial tightly closed.
- Use clean techniques and appropriate lab PPE.
- Maintain labeling and internal documentation for traceability.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Trubacova R, Drastichova Z, Novotny J. Biochemical and physiological insights into TRH receptor-mediated signaling. Front Cell Dev Biol. 2022;10:981452. Published 2022 Sep 6. doi:10.3389/fcell.2022.981452
- Yang F, Zhang H, Meng X, et al. Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res. 2022;32(9):858-861. doi:10.1038/s41422-022-00646-6
- National Center for Biotechnology Information. PubChem Compound Summary for CID 638678, Protirelin. https://pubchem.ncbi.nlm.nih.gov/compound/Protirelin.
- Nillni EA. Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs. Front Neuroendocrinol. 2010;31(2):134-156. doi:10.1016/j.yfrne.2010.01.001
- Engel S, Gershengorn MC. Thyrotropin-releasing hormone and its receptors–a hypothesis for binding and receptor activation. Pharmacol Ther. 2007;113(2):410-419. doi:10.1016/j.pharmthera.2006.09.004
What is TRH (Thyrotropin-Releasing Hormone) (20 mg)?
TRH (thyrotropin-releasing hormone) is a short, naturally occurring peptide commonly used in laboratory research to study neuroendocrine signaling and hormone-regulation pathways. It is often grouped with brain, cognitive, and nootropic peptides, as it serves as a tool compound in studies of hypothalamic–pituitary signaling, receptor activity, and neurotransmitter-linked endocrine responses. Its small size and well-characterized structure make it suitable for controlled experimental models.
Product Specifications
- CAS Number: 24305-27-9
- Peptide Sequence: Pyr-His-Pro-NH₂
- Category: Peptide
- Subcategory: Brain, Cognitive & Nootropic Peptides
- Molecular Weight:38 g/mol
- Molecular Formula: C₁₆H₂₂N₆O₄
- Synonyms: Protirelin
- Purity: ≥99%
- Packaging Format: 20 mg
- Storage Conditions: Store at -20°C; avoid light exposure
- Compliance Notice: For laboratory research use only
Key Characteristics of TRH (Thyrotropin-Releasing Hormone) (20 mg)
- Research-Grade Peptide Tool: Used in controlled neuroendocrine study designs.
- High Purity (≥99%): Supports reproducibility across experiments.
- Well-Defined Tripeptide Structure: Suitable for receptor and pathway research.
- Neuroendocrine Relevance: Common in hypothalamic–pituitary axis studies.
- Storage: Store at -20°C; avoid exposure to light.
How TRH (Thyrotropin-Releasing Hormone) (20 mg) Supports Research
In laboratory settings, TRH is used to investigate TRH receptor activity and signaling pathways involved in endocrine regulation. It supports studies exploring pituitary hormone-release pathways, neuroendocrine communication, and how peptide signals influence downstream cellular behavior in controlled in vitro or in vivo research models.
Research Applications & Usage Information
TRH (20 mg) is commonly used in laboratory research for:
- TRH Receptor Research: Evaluating receptor interaction and signaling responses.
- Neuroendocrine Pathway Studies: Supporting hypothalamic–pituitary axis research.
- Hormone Signaling Models: Used in studies of regulated hormone release.
- Cell Signaling Assays: Mapping downstream pathway activation patterns.
- Method Development: Useful as a reference peptide in assay validation.
- Comparative Research: Included in studies comparing peptide signaling profiles.
Handling and Storage Recommendations
- Store at -20°C; avoid light exposure.
- Minimize time at room temperature. Make sure to reduce exposure during handling.
- Keep vial tightly closed.
- Use clean techniques and appropriate lab PPE.
- Maintain labeling and internal documentation for traceability.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Trubacova R, Drastichova Z, Novotny J. Biochemical and physiological insights into TRH receptor-mediated signaling. Front Cell Dev Biol. 2022;10:981452. Published 2022 Sep 6. doi:10.3389/fcell.2022.981452
- Yang F, Zhang H, Meng X, et al. Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res. 2022;32(9):858-861. doi:10.1038/s41422-022-00646-6
- National Center for Biotechnology Information. PubChem Compound Summary for CID 638678, Protirelin. https://pubchem.ncbi.nlm.nih.gov/compound/Protirelin.
- Nillni EA. Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs. Front Neuroendocrinol. 2010;31(2):134-156. doi:10.1016/j.yfrne.2010.01.001
- Engel S, Gershengorn MC. Thyrotropin-releasing hormone and its receptors–a hypothesis for binding and receptor activation. Pharmacol Ther. 2007;113(2):410-419. doi:10.1016/j.pharmthera.2006.09.004