Tirzepatide 10mg
Strength: 10 mg
CAS: 2023788-19-2
Chemical Formula: C₂₂₅H₃₄₈N₄₈O₆₈
Molecular weight: 4813.48 g/mol
Peptide Sequence: Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys(C20-linker)-Ile-Ala-Gln-Lys-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂
Synonyms: P1206, LY3298176, tirzepatida, tirzepatidum, OYN3CCI6QE
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
Tirzepatide, also known as LY3298176 or P1206, is a synthetic dual receptor–targeted peptide supplied as a high-purity lyophilized powder for laboratory research. It is widely studied in metabolic and endocrine research models to investigate hormone receptor signaling, glucose regulation pathways, and energy balance mechanisms under controlled experimental conditions.
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INFORMATION
What is Tirzepatide (10 mg)?
Tirzepatide is a synthetic, modified peptide used as a research reagent in studies on incretin receptor biology. It can activate both GIP and GLP-1 receptors, making it a valuable tool in experimental designs focused on receptor-driven signaling, downstream biomarker changes, and pathway selectivity.
With a 39-amino acid backbone and lipid conjugation, Tirzepatide is also relevant to research evaluating how peptide modifications influence biological behavior in matrices and model systems.
Product Specifications
- Synonyms: LY3298176, P1206, tirzepatida, tirzepatidum
- CAS Number: 2023788-19-2
- Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
- Molecular Weight: 4813.48 g/mol
- Peptide Sequence:
Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys(C20)-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ - Purity: ≥95% (verified by HPLC and mass spectrometry)
- Packaging Format: 10 mg lyophilized powder in a sealed research-grade vial
- Storage Conditions: Store 2–8 °C (≤–20 °C long term). Protect from light.
- Intended Use: For Laboratory Research Use Only
Key Characteristics of Tirzepatide (10 mg)
- Dual incretin-receptor work: Supports studies that track the behavior of two receptor targets within the same experimental setup.
- Commonly referenced in mechanistic literature: Frequently discussed in “twincretin” research and comparative incretin pharmacology.
- Important structural features: Lipid conjugation and a defined composition enable controlled comparisons in peptide design projects.
- Storage-sensitive reagent: Protect from light during handling.
How Tirzepatide (10 mg) Supports Research
Tirzepatide is used to explore how incretin receptor activation leads to downstream signaling and measurable system changes in experimental models. Depending on the model, this may involve receptor signaling measurements, functional assays related to metabolic pathways, and comparisons between dual-agonist tools and more selective pathway probes.
Research Applications & Usage Information
- Cell-based signaling assays: Evaluation of receptor activation and downstream signaling responses.
- Model-based metabolic pathway research: Investigating glucose and nutrient response pathways in experimental systems.
- Comparative agonist profiling: Benchmarking dual-target behavior against single-target incretin tools (depending on the experimental design).
- Structure-function investigations: Exploring how peptide modifications influence stability and exposure in research settings.
Handling and Storage Recommendations
- Minimize light exposure during handling to protect the integrity of the peptide.
- Follow good laboratory practices for labeling, storage, and handling to reduce contamination risk.
- Store according to standard laboratory protocols, ensuring conditions are suitable for long-term storage.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Willard FS, Douros JD, Gabe MB, et al. Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist. JCI Insight. 2020;5(17):e140532. Published 2020 Sep 3. doi:10.1172/jci.insight.140532
- Fisman EZ, Tenenbaum A. The dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide: a novel cardiometabolic therapeutic prospect. Cardiovasc Diabetol. 2021;20(1):225. Published 2021 Nov 24. doi:10.1186/s12933-021-01412-5
- Coskun T, Sloop KW, Loghin C, et al. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept. Mol Metab. 2018;18:3-14. doi:10.1016/j.molmet.2018.09.009
What is Tirzepatide (10 mg)?
Tirzepatide is a synthetic, modified peptide used as a research reagent in studies on incretin receptor biology. It can activate both GIP and GLP-1 receptors, making it a valuable tool in experimental designs focused on receptor-driven signaling, downstream biomarker changes, and pathway selectivity.
With a 39-amino acid backbone and lipid conjugation, Tirzepatide is also relevant to research evaluating how peptide modifications influence biological behavior in matrices and model systems.
Product Specifications
- Synonyms: LY3298176, P1206, tirzepatida, tirzepatidum
- CAS Number: 2023788-19-2
- Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
- Molecular Weight: 4813.48 g/mol
- Peptide Sequence:
Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys(C20)-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ - Purity: ≥95% (verified by HPLC and mass spectrometry)
- Packaging Format: 10 mg lyophilized powder in a sealed research-grade vial
- Storage Conditions: Store 2–8 °C (≤–20 °C long term). Protect from light.
- Intended Use: For Laboratory Research Use Only
Key Characteristics of Tirzepatide (10 mg)
- Dual incretin-receptor work: Supports studies that track the behavior of two receptor targets within the same experimental setup.
- Commonly referenced in mechanistic literature: Frequently discussed in “twincretin” research and comparative incretin pharmacology.
- Important structural features: Lipid conjugation and a defined composition enable controlled comparisons in peptide design projects.
- Storage-sensitive reagent: Protect from light during handling.
How Tirzepatide (10 mg) Supports Research
Tirzepatide is used to explore how incretin receptor activation leads to downstream signaling and measurable system changes in experimental models. Depending on the model, this may involve receptor signaling measurements, functional assays related to metabolic pathways, and comparisons between dual-agonist tools and more selective pathway probes.
Research Applications & Usage Information
- Cell-based signaling assays: Evaluation of receptor activation and downstream signaling responses.
- Model-based metabolic pathway research: Investigating glucose and nutrient response pathways in experimental systems.
- Comparative agonist profiling: Benchmarking dual-target behavior against single-target incretin tools (depending on the experimental design).
- Structure-function investigations: Exploring how peptide modifications influence stability and exposure in research settings.
Handling and Storage Recommendations
- Minimize light exposure during handling to protect the integrity of the peptide.
- Follow good laboratory practices for labeling, storage, and handling to reduce contamination risk.
- Store according to standard laboratory protocols, ensuring conditions are suitable for long-term storage.
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Willard FS, Douros JD, Gabe MB, et al. Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist. JCI Insight. 2020;5(17):e140532. Published 2020 Sep 3. doi:10.1172/jci.insight.140532
- Fisman EZ, Tenenbaum A. The dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide: a novel cardiometabolic therapeutic prospect. Cardiovasc Diabetol. 2021;20(1):225. Published 2021 Nov 24. doi:10.1186/s12933-021-01412-5
- Coskun T, Sloop KW, Loghin C, et al. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept. Mol Metab. 2018;18:3-14. doi:10.1016/j.molmet.2018.09.009




