Did you know that in 2019, about 528 million people worldwide lived with osteoarthritis (OA)? This statistic emphasizes the significant 113% increase in patients with OA since 1990, with more and more individuals having to deal with its chronic symptoms and negative effects on their mobility.
Unfortunately, OA has yet to find a cure in the medical field, urging individuals to seek effective solutions to manage its symptoms. Due to advancements, medical professionals may offer Durolane injections to temporarily relieve OA pain and improve joint mobility.
This article will discuss Durolane’s generic name, its pharmacological properties, how it relieves osteoarthritis symptoms, and understanding this key ingredient’s role in viscosupplementation therapy.
Key Takeaways
- Sodium hyaluronate acts as a lubricant and shock absorber for the joints, enhancing joint function and reducing pain.
- This substance naturally occurs in the joints and the synovial fluid, making it a safe solution for addressing knee OA.
- Viscosupplementation therapy often capitalizes on sodium hyaluronate, which is injected into the affected joint.
- Bioventus developed the recommended Durolane dosage of 3 mL, which contains high-molecular-weight hyaluronic acid (HA) and NASHA technology to crosslink HA molecules for longer-lasting effects.
About: Medica Depot is your trusted all-in-one supplier, offering a range of high-quality medical injectables and supplies. If you’re looking to buy Durolane online, our dedicated sales agents can give you proper guidance. We offer a worry-free experience in searching for the best and most popular products on the market. Whether for health professionals, plastic surgeons, dermatologists, licensed estheticians, or other specialists, we can offer genuine, brand-name products you may need. With Medica Depot, we prioritize serving you better to improve the patient’s quality of life.
What is Sodium Hyaluronate?
Durolane offers a single-injection therapy to treat individuals suffering from knee osteoarthritis (OA) and its chronic symptoms. When comparing treatments like Durolane vs Synvisc, these injections utilize hyaluronic acid for effective treatments.
Furthermore, when considering the treatment, individuals and medical professionals may look into Durolane’s generic name, sodium hyaluronate. This is the clear, viscous gel in the body, like the joint tissue and fluid surrounding the joints.
Sodium hyaluronate acts as a lubricant and shock absorber for the joints, enhancing joint function and reducing pain. Durolane is a brand of sodium hyaluronate utilized to treat knee pain caused by OA when the first line of therapy is ineffective.
This substance naturally occurs in the joints and the synovial fluid, making it a safe solution for addressing knee OA. It maintains joint health through lubrication, cushioning, and supporting joint movement. When injected directly into the knee joint, the appropriate Durolane dosage relieves pain and improves mobility for up to six months or longer.
Pharmacological Properties of Sodium Hyaluronate
Sodium hyaluronate is part of the high-molecular-weight hyaluronic acid fraction, which helps balance the synovial fluid’s viscoelasticity. It also activates the tissue repair processes in the joint cartilage, improving joint function and reducing pain.
Viscosupplementation therapy often capitalizes on sodium hyaluronate, which is injected into the affected joint. This thick fluid lubricates and cushions the joint, minimizing the symptoms brought by knee osteoarthritis (OA). Medical professionals may only recommend viscosupplementation when the first line of treatments has not taken effect.
Compared to other OA treatments, nonsteroidal anti-inflammatory drugs (NSAIDs) only provide short-term pain relief for the symptoms; duloxetine can also temporarily address chronic pain, while physical therapy is best used alongside another OA treatment for muscle strengthening and joint flexibility.
Clinical Efficacy and Development of Sodium Hyaluronate
Bioventus produced the Durolane single-injection therapy to address knee osteoarthritis (OA) symptoms. Bioventus maintains its dedication to transforming OA and joint-related treatments. In 2019, Bioventus initiated a collaborative development agreement with MTF Biologics to create an advanced placental tissue product for knee OA jointly. Their partnership also explores broader applications beyond knee OA.
The manufacturer developed the recommended Durolane dosage of 3 mL, which contains high-molecular-weight hyaluronic acid (HA) and NASHA technology to crosslink HA molecules for longer-lasting effects. Moreover, the US Food and Drug Administration has approved Durolane injections temporarily treating knee OA.
The clinical studies evaluated reveal consistent and lasting relief of knee osteoarthritis (OA) symptoms after a single NASHA injection. Furthermore, NASHA exhibits excellent biocompatibility as an intra-articular OA therapy, evidenced by the minimal occurrence of adverse events associated with treatment.
A study by Velasco et al. (2017) indicates that using NASHA for viscosupplementation effectively alleviates symptoms of rhizarthrosis and is well tolerated by patients. Various patient testimonials highlight Durolane dosage’s efficacy, potential Durolane side effects, and safety.
Conclusion
Understanding Durolane and its generic name, sodium hyaluronate, shed light on its role in managing the chronic symptoms of knee osteoarthritis (OA). By highlighting its pharmacological properties and clinical efficacy, it emphasizes sodium hyaluronate’s significance in viscosupplementation therapy.
Additionally, the information on Durolane’s development, dosage, and FDA approval offers valuable insights into its potential for knee OA treatment. This underscores its substantial impact in providing consistent and long-lasting relief for individuals suffering from knee OA. Clinical studies and patient testimonials demonstrate its safety and efficacy.
FAQs
1. What is the key role of Sodium Hyaluronate in managing knee osteoarthritis (OA) symptoms?
Sodium Hyaluronate acts as a lubricant and shock absorber for the joints, enhancing joint function and reducing pain, making it a safe and effective solution for addressing knee OA.
2. What is the recommended Durolane dosage and its composition?
The recommended Durolane dosage is 3 mL, containing high-molecular-weight hyaluronic acid (HA) and NASHA technology, which crosslinks HA molecules for longer-lasting effects.
3. How does Durolane compare to other treatments for knee osteoarthritis?
Durolane offers single-injection therapy, providing consistent and long-lasting relief for knee osteoarthritis symptoms, distinguishing itself from short-term relief treatments such as NSAIDs and duloxetine.
References
- WHO. (2023, July 14). Osteoarthritis. Www.who.int; World Health Organization. https://www.who.int/news-room/fact-sheets/detail/osteoarthritis
- Velasco, E., Ribera, M. V., & Pi, J. (2017). Single-arm open-label study of Durolane (NASHA nonanimal hyaluronic acid) for the treatment of osteoarthritis of the thumb. Open access rheumatology: research and reviews, 9, 61–66. https://doi.org/10.2147/OARRR.S128675
