An individual showing their smooth and glowing facial skin.

Innovative treatments like injectable fillers have transformed the world of aesthetic medicine, helping people address a wide range of skin concerns. Over the years, more patients have turned to these non-surgical solutions to enhance their appearance, driven by advancements in technology and improved results.

Among the most popular options, hyaluronic acid fillers such as Neuramis and Restylane have become leading choices for facial rejuvenation. These unique formulations offer patients a youthful look without the need for surgery.

In this article, we’ll explore the differences between Neuramis vs Restylane fillers, including their formulations, treatment areas, before-and-after results, the longevity of effects, and potential side effects.

Key Takeaways

  • While having a similar active ingredient in hyaluronic acid, Neuramis and Restylane differ in their cross-linking and stabilizing formulation technologies.
  • The collection of Neuramis and Restylane dermal fillers offers versatility in various treatment areas and concerns for the facial skin.
  • The visual evidence highlights the potency of these dermal fillers in delivering effective facial rejuvenation and restoring the glow in these individuals.
  • While Restylane has earned FDA approval, there is still no word about Neuramis FDA approval in the United States.
  • Both injections can last within six to twelve months, while several Restylane formulations can extend up to 18 months.

About: Medica Depot is your trusted all-in-one supplier, offering a range of high-quality medical injectables and supplies. Buy Neuramis online at Medica Depot today! Whether for health professionals, plastic surgeons, dermatologists, licensed estheticians, or other specialists, we can offer genuine, brand-name products you may need. With Medica Depot, we prioritize serving you better to improve the patient’s quality of life.

Introduction to Neuramis and Restylane

A medical professional administering a facial injection into a patient.

When considering hyaluronic acid-based dermal fillers for facial rejuvenation, aesthetic professionals often compare Neuramis and Restylane. These prominent brands have emerged as safe and efficient options in aesthetic medicine, enhancing facial volume, smoothing visible signs of aging, and restoring a youthful appearance.

  • Neuramis: Developed by Medytox, Neuramis uses advanced SHAPE technology to create a high-quality filler with longer-lasting effects. It is known for its smooth consistency and versatility in treating various areas of the face.
  • Restylane: Restylane, by Galderma, is one of the most recognized dermal fillers worldwide and is known for its diverse range of formulations. It has been used for decades to effectively smooth wrinkles, enhance lips, and restore facial volume.

Formulation and Composition

Medytox produced Neuramis fillers and harnesses the potency of high-quality hyaluronic acid. They utilized a unique Stabilized Hyaluronic Acid and Purification Enhancement (SHAPE) technology for these Neuramis fillers. This involves a two-step cross-linking process, ensuring stabilization and high formulation purification.

In contrast, Galderma developed a Restylane collection of fillers and capitalized on a hyaluronic acid (HA) formulation that mimics the natural HA in the body with minimal cross-linking. Depending on their injections’ approved treatment areas, Restylane uses NASHA® and XpresHAn technologies for their formulations.

While hyaluronic acid is a similar active ingredient, Neuramis and Restylane differ in cross-linking and stabilizing formulation technologies. These distinct methods affect the dermal filler’s stability, duration of effects, and suitability for specific facial areas.

Treatment Areas and Effectiveness

The collection of Neuramis injectables offers versatility in treating various facial areas and addressing multiple skin concerns. Their formulation is suitable for sensitive and delicate facial regions, making them a reliable choice for different needs.

  • Neuramis Deep: Targets moderate to severe wrinkles and folds.
  • Neuramis Light Lidocaine: Addresses fine wrinkles and improves skin elasticity and structure.
  • Neuramis Lidocaine and Neuramis Deep Lidocaine: Designed for lower face wrinkles and folds, specifically nasolabial folds.
  • Neuramis Volume Lidocaine: Suitable for facial wrinkles and folds, chin and cheek augmentation, and facial contouring.

Meanwhile, Restylane’s collection of fillers offers specific formulations designed for a wide range of facial areas and skin issues. Each Restylane product is tailored to ensure optimal and satisfactory outcomes based on the targeted treatment area.

  • Restylane and Restylane Refyne: Moderate to severe facial wrinkles and folds.
  • Restylane-L: Moderate to severe facial wrinkles and folds, and lip enhancement.
  • Restylane Contour: Cheek augmentation and mid-face contouring.
  • Restylane Defyne: Chin augmentation and treatment of deep facial wrinkles and folds.
  • Restylane Kysse: Lip augmentation and upper perioral wrinkles.
  • Restylane Lyft: Suitable for cheek augmentation, dorsal hand rejuvenation, and facial wrinkles and folds.
  • Restylane Silk: Lip enhancement and perioral wrinkle treatment.
  • Restylane Eyelight: Targets infraorbital hollowing.

Both dermal fillers effectively address visible signs of aging and volume loss in the facial region. Neuramis excels in treating sensitive areas due to its high purity and advanced SHAPE technology, which provides stability and smooth consistency. On the other hand, Restylane offers a diverse range of formulations specifically tailored for different facial areas, ensuring long-lasting and natural-looking results.

Patient Experiences and Longevity

Many individuals have shared before-and-after photos of their Neuramis and Restylane treatments. This visual evidence highlights the potency of these dermal fillers to deliver effective facial rejuvenation and restore the glow in these individuals. These patients have received Neuramis and Restylane injections for their aesthetic enhancements.

Neuramis's patients' before and after photos of their facial rejuvenation enhancement.
Photo Source: Korean Fillers
A Neuramis-treated patient's before and after photo of their lip enhancement.
Photo Source: Angelite Aesthetics via Neuramis UK
A Restylane-treated patient's before and after photo of their nasolabial fold and cheeks enhancements.
Photo Source: Restylane
A Restylane-treated patient's before and after photo of their symmetrical lips post-treatment.
Photo Source: Celibre

The first two photos highlight Neuramis results that generally last between 6 to 12 months, influenced by the treatment area and individual metabolism. Similarly, the last two images showcase Restylane outcomes that typically endure 6 to 12 months, with certain formulations extending up to 18 months.

Safety Profile and Side Effects

Neuramis fillers have undergone extensive clinical tests and trials to receive CE-mark approval and reach the aesthetic markets in various European and Asian countries. However, the product has yet to gain FDA approval in the United States.

In comparison, the Restylane collection has received a green light from the FDA and is widely used globally. This shows its well-established safety profile and the rigorous clinical trials these injectables’ underwent to prove their safety and efficacy.

Common Side Effects and Potential Risks

Despite the difference in their FDA approvals, aesthetic professionals should discuss the Restylane and Neuramis filler side effects post-treatment with patients. These side effects are typically temporary and may subside within a few days to a week once the body adapts to the material.

  • Common Neuramis Side Effects: Redness, swelling, bruising, tenderness, and itching at the injection site.
  • Common Restylane Side Effects: Swelling, redness, pain, bruising, tenderness, and itching at the injection site.

In addition to common side effects, rare but potentially severe adverse events may occur due to factors such as individual treatment response, inaccurate administration technique, or improper post-treatment care. These potential risks include:

  • Allergic Reactions: Symptoms may include severe redness, swelling, itching, hives, rash, or difficulty breathing.
  • Infection: This side effect can manifest as persistent redness, pain, warmth at the injection site, or fever.
  • Filler Migration: Patients may notice lumps, asymmetry, and changes in the treatment area’s appearance.

These symptoms may also occur with other dermal filler injections. If these symptoms arise, it is crucial for individuals to seek immediate medical attention, ensuring prompt action and appropriate management to avoid further complications.

Conclusion

The comparison between Neuramis vs Restylane highlights the effectiveness of hyaluronic acid-based dermal fillers in aesthetic medicine. Both brands offer versatile, non-surgical solutions for facial rejuvenation, with Neuramis featuring unique SHAPE technology and Restylane utilizing NASHA and XpresHAn technologies.

Before-and-after results further demonstrate their ability to restore a youthful appearance, with the choice between them depending on individual preferences, skin concerns, and aesthetic goals.

FAQs

1. What are the main differences between Neuramis and Restylane dermal fillers?

Neuramis and Restylane differ in their cross-linking and stabilizing formulation technologies, affecting the stability, duration of effects, and suitability for specific facial areas.

2. Which treatment areas do Neuramis and Restylane target?

Neuramis and Restylane offer specific formulations for various facial skin issues and treatment sites, addressing wrinkles, folds, facial volume, and contouring concerns.

3. How long do Neuramis and Restylane injections last?

Both Neuramis and Restylane injections can last within six to twelve months, with several Restylane formulations extending up to 18 months.

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References

  1. Eppley, B. L., & Dadvand, B. (2006). Injectable soft-tissue fillers: clinical overview. Plastic and reconstructive surgery, 118(4), 98e–106e. https://doi.org/10.1097/01.prs.0000232436.91409.30
  2. Hyaluronic Acid Filler  Neuramis®. (n.d.). Medytox.com. Retrieved October 4, 2024, from https://www.medytox.com/page/neuramis_en?site_id=en