DYSPORT® 300u (English Alternative)

DYSPORT® 300u – Key Features and Benefits

DYSPORT® 300 Units is a botulinum toxin type A product used for both aesthetic and therapeutic purposes. It works by blocking nerve signals to muscles, thereby reducing muscle contractions that cause wrinkles or spasticity.

• Contains clostridium botulinum type A neurotoxin, from Hall strain

• 300 units per vial, in powder form for reconstitution

• Onset of effect: within 2–3 days, peak at 1–2 weeks

• Duration of action: up to 4 months

• Used for glabellar lines, cervical dystonia, blepharospasm, and more

• Proven efficacy and consistent dosing for repeat treatments

• Similar indications to Botox®, but with a different unit equivalence

DYSPORT® 300u – Indications

DYSPORT® 300u is indicated for use in adults and children for several muscle-related conditions, including both medical and cosmetic uses.

• Aesthetic indication:

  • Temporary improvement in moderate to severe glabellar lines

• Therapeutic indications (adults):

  • Cervical dystonia (spasmodic torticollis)

  • Upper limb spasticity

  • Blepharospasm

• Pediatric use:

  • Lower limb spasticity due to cerebral palsy (≥2 years old)

• Always administered by a trained medical professional

DYSPORT® 300u – Ingredients

DYSPORT® contains botulinum toxin type A and stabilizers to maintain potency. The powder is white and must be reconstituted prior to use.

• Active ingredient:

  • Clostridium botulinum toxin type A – 300 units per vial

• Excipients:

  • Human albumin

  • Lactose monohydrate

• Formulation:

  • Lyophilized powder for injection

• Diluent:

  • 0.9% sodium chloride (preservative-free) for reconstitution

DYSPORT® 300u – How To Use

DYSPORT® 300u must be reconstituted and administered by qualified professionals, with dosing adjusted based on indication, muscle mass, and individual response.

• Route: Intramuscular injection

• Dilution: Typically reconstituted with 1.5 to 2.5 mL of 0.9% NaCl

• Injection technique:

  • Varies based on use (e.g., five-point injection for glabellar lines)

• Onset: 2–3 days; peak effect in 1–2 weeks

• Duration: 12–16 weeks (3–4 months)

• Storage:

  • Store unopened vials refrigerated (2–8°C)

  • Use reconstituted solution within 24 hours

DYSPORT® 300u – Side Effects

DYSPORT® has a well-established safety profile, though some patients may experience localized or systemic reactions. Side effects vary by treatment area and dosage.

Common side effects (aesthetic use):

• Headache

• Eyelid drooping (ptosis)

• Injection site discomfort

• Dry eyes or tearing

Common side effects (therapeutic use):

• Muscle weakness

• Fatigue

• Dysphagia (difficulty swallowing)

• Flu-like symptoms

Rare but serious effects:

• Allergic reactions (rash, itching, difficulty breathing)

• Systemic botulinum toxin spread (e.g., difficulty swallowing or breathing)

• Antibody formation (may reduce effectiveness)

DYSPORT® 300u – Clinical Studies

DYSPORT® has been extensively studied across multiple indications, with robust data supporting its efficacy and tolerability.

• Glabellar line trials:

  • Showed significant wrinkle reduction compared to placebo

  • Improvement maintained for up to 4 months

• Cervical dystonia:

  • Effective in reducing neck pain and muscle spasms

  • Repeated doses were safe and well tolerated

• Pediatric lower limb spasticity:

  • Demonstrated improved gait pattern and spasticity control

  • No increase in adverse event frequency over multiple cycles

DYSPORT® 300u – Manufacturer Information

DYSPORT® is manufactured by Ipsen Biopharm Ltd., a global biopharmaceutical company specializing in neurology, oncology, and rare diseases.

• Manufacturer: Ipsen Biopharm Ltd., Wrexham, UK

• Brand owner: Ipsen Pharma, France

• Marketed internationally under: DYSPORT®

• Approved for use in over 70 countries

• Distributed by licensed partners worldwide

• Requires cold chain handling for stability

DYSPORT® 300u – FAQ (Based on Google SERP)

How many units of DYSPORT® equal Botox®?
The general conversion ratio is 2.5 to 3 units of DYSPORT® = 1 unit of Botox®, though this varies by use and patient.

How long does DYSPORT® last?
Results typically last 3 to 4 months, similar to Botox®.

When will I see results from DYSPORT®?
Most patients notice results within 2–3 days, with full effect in 7–14 days.

Can DYSPORT® be used for the same areas as Botox®?
Yes. It’s approved for glabellar lines, cervical dystonia, and other muscle conditions, often used as a Botox alternative.

Is DYSPORT® safe for long-term use?
Yes. Clinical data support safe repeated use with consistent efficacy over multiple injection cycles.

What’s the difference between DYSPORT® and Botox®?
DYSPORT® diffuses more broadly, which may benefit larger treatment areas. Botox® may stay more localized.

Can children receive DYSPORT®?
Yes, for specific conditions such as lower limb spasticity in cerebral palsy, for children aged 2 and older.