An individual receiving an injection into their nasolabial folds.

According to the American Board of Cosmetic Surgery, volume loss is a key contributor to many visible signs of aging. Thinning facial tissues lead to fine lines around the nose and mouth, as well as hollowed cheeks. As a result, more people are turning to aesthetic treatments to address these concerns and restore a youthful appearance.

Injectable dermal fillers offer a non-surgical solution for enhancing facial features, restoring lost volume, and smoothing out signs of aging. Among the most notable options are Ellanse and Sculptra, which stand out for their ability to stimulate collagen production, offering long-lasting results that rejuvenate the skin from within.

This article will compare Ellanse vs Sculptra, focusing on their formulations, mechanisms of action, ideal treatment areas, and the longevity of their effects.

Key Takeaways

  • Proper selection of dermal filler can ensure natural-looking results and minimize the risks of complications throughout the cycle.
  • The Europe-approved Ellanse dermal filler capitalizes on the potency of polycaprolactone, while the US FDA-approved Sculptra utilizes poly-L-lactic acid.
  • Ellanse delivers immediate and enduring treatment outcomes, while Sculptra offers gradual, lasting results.
  • Both dermal fillers effectively address aging signs in the mid-face region, targeting and minimizing fine lines, wrinkles, and folds.

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Introduction to Ellanse and Sculptra

An individual receiving an injection to address their nasolabial folds.

Dermal fillers have become one of the most popular choices for facial rejuvenation, especially following the success of botulinum toxin injections. These injectables address volume loss, enhance facial contours, and reduce visible signs of aging by restoring fullness or stimulating collagen production. As a result, patients experience smoother, firmer, and more youthful-looking skin.

Choosing the right dermal filler is critical to achieving specific aesthetic goals. When selecting a filler, aesthetic professionals must consider several factors:

  • Severity of skin concern
  • Skin type and condition
  • Potential medical concerns (such as hypersensitivity)
  • Longevity of the filler’s effects
  • How well the patient responds to the treatment

Ellanse and Sculptra are advanced dermal fillers known for combating facial aging through different mechanisms. Medical professionals often compare Ellanse and Sculptra due to their proven effectiveness and unique compositions, making them ideal for addressing specific patient needs.

Formulation and Composition

Ellanse and Sculptra stand out for their unique compositions, differentiating them from traditional dermal fillers that typically use hyaluronic acid. Their advanced formulations stimulate the body’s collagen production, allowing for long-lasting, natural-looking results.

Ellanse is approved in Europe and features polycaprolactone (PCL) microspheres suspended in a carboxymethyl cellulose gel. This combination allows Ellanse to provide both immediate volume restoration and long-lasting results as the PCL microspheres gradually stimulate collagen production. Unlike traditional hyaluronic acid fillers, which rely on volumization alone, Ellanse promotes structural skin improvement over time, enhancing its longevity.

Sculptra, approved by the US Food and Drug Administration, uses poly-L-lactic acid (PLLA) particles in its formulation. Unlike Ellanse, Sculptra’s effects are more gradual. PLLA stimulates collagen production over several months, leading to a natural, progressive improvement in skin texture and volume. While Sculptra may not offer immediate volumizing effects like Ellanse or hyaluronic acid fillers, its gradual collagen-boosting mechanism results in long-lasting improvements lasting up to two years or more.

Mechanism of Action

Ellanse uses polycaprolactone (PCL) microspheres to deliver a dual-action approach. Upon injection, Ellanse immediately corrects wrinkles, lines, and folds by adding volume to the skin. Over time, the PCL microspheres gradually stimulate the body’s natural collagen production, which addresses the deeper causes of aging, such as the loss of skin structure and elasticity.

This process allows Ellanse to provide immediate volumization while promoting long-term skin rejuvenation lasting several years.

On the other hand, Sculptra uses poly-L-lactic acid (PLLA) particles that work beneath the skin’s surface. When injected, the PLLA particles are absorbed by the body and trigger a gradual increase in collagen production. This slow process helps restore the skin’s structure over time, enhancing volume and texture in a way that looks natural.

Unlike Ellanse, Sculptra does not offer immediate results but instead works progressively over several months, with visible improvements lasting for up to two years or more.

Ideal Treatment Areas

An aesthetic professional holding an injection before the treatment process.

Individuals should understand the approved and ideal treatment areas for Ellanse and Sculptra. Knowledge about the proper treatment procedure and areas can minimize the potential Sculptra and Ellanse problems throughout their procedure.

  • Ellanse Treatment Areas and Concerns: Temples, mid-face, chin, jaw, marionette lines, and nasolabial folds.
  • Sculptra Treatment Areas and Concerns: Cheek region, nasolabial fold contour deficiencies, fine lines, and wrinkles.

Both Ellanse and Sculptra target the mid-face region and effectively address signs of aging. However, Ellanse is preferred for patients who want immediate volume restoration, especially in areas like the chin and jaw, where structural support is critical. Sculptra, by contrast, is more suitable for individuals who are comfortable with gradual, progressive results, as it takes time for the collagen stimulation to visibly improve skin texture and volume.

Effectiveness and Longevity

An individual flexing their smooth and clear skin.

Aesthetic professionals should discuss the clinical evidence proving these dermal fillers’ safety and efficacy when comparing Ellanse vs Sculptra. Many studies have delved into these dermal fillers, equipping individuals with clinical data to ensure their effectiveness in addressing the facial region.

A study highlights that Ellanse effectively corrects age-related volume loss and is versatile in its applications. It primarily restores volume, redefines facial contours, and reduces wrinkles. The safety profile, ease of injection, and adjustable longevity make Ellansé a preferred choice in our practice, ensuring high patient satisfaction.

A randomized controlled trial reported that injectable PLLA treatments were well tolerated and significantly reduced moderate to severe cheek lines and wrinkles while enhancing skin quality. The effectiveness remained consistent over the 12-month study period, with subjects expressing high satisfaction, noting a natural-looking appearance, and showing enthusiasm for repeat treatments.

According to Ellanse, the typical duration of effects can last from 18 months to three years, and onset of action immediately after treatment. In contrast, Sculptra’s longevity of results may last up to two years, and results become noticeable after a month post-treatment. Both fillers are effective; however, Ellanse lasts longer than Sculptra.

Conclusion

Both Ellanse and Sculptra offer distinct approaches to facial rejuvenation. Ellanse’s polycaprolactone formulation provides immediate and long-lasting results, which is ideal for those seeking quick outcomes. Sculptra, using poly-L-lactic acid, promotes gradual collagen production, delivering sustained improvements over time.

When choosing between these fillers, factors such as specific skin concerns, skin type, and desired longevity of results should be carefully considered. Both injectables have demonstrated safety and effectiveness in clinical studies. Consulting with an aesthetic professional is essential to determine the most suitable option based on individual needs and treatment goals.

FAQs

1. What are the key differences between Ellanse and Sculptra?

Ellanse uses polycaprolactone (PCL) to deliver immediate and enduring results, while Sculptra utilizes poly-L-lactic acid (PLLA) to offer gradual, lasting improvements.

2. Which areas do Ellanse and Sculptra target?

Both fillers effectively address aging signs in the mid-face region, targeting and minimizing fine lines, wrinkles, and folds.

3. How do I choose between Ellanse and Sculptra for my aesthetic treatment?

Factors to consider include the severity of your skin concern, skin type and condition, medical concerns, the longevity of outcomes, and the patient’s treatment response. Consulting with an aesthetic professional can help determine the best option for their needs and goals.

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References

  1. Injectable Fillers Guide. (2014, July 11). American Board of Cosmetic Surgery. https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/injectable-fillers-guide/
  2. de Melo, F., Nicolau, P., Piovano, L., Lin, S. L., Baptista-Fernandes, T., King, M. I., Camporese, A., Hong, K., Khattar, M. M., & Christen, M. O. (2017). Recommendations for volume augmentation and rejuvenation of the face and hands with the new generation polycaprolactone-based collagen stimulator (Ellansé®). Clinical, cosmetic and investigational dermatology, 10, 431–440. https://doi.org/10.2147/CCID.S145195