The latest report from the American Society of Plastic Surgeons indicates that neuromodulator injections were the most popular minimally invasive procedure in 2022, with over 8.7 million treatments performed. This significant figure underscores the confidence that both patients and professionals place in these injections to achieve facial rejuvenation and a youthful appearance.
Neuromodulator injections use botulinum toxin to relax wrinkles in the facial areas. These treatments help individuals achieve a smoother facial appearance by addressing signs of aging. Among various brand-name injections, Xeomin and Jeuveau are notable for their demonstrated safety and effectiveness in reducing frown lines and wrinkles.
This article will compare Xeomin vs Jeuveau, their formulations, clinical efficacy, approved uses, duration of results, and cost comparison.
Key Takeaways
- The comparison between Xeomin vs Jeuveau aims to differentiate their distinct formulations, common uses, benefits, and potential risks associated with their treatments.
- When injected, Xeomin and Jeuveau offer similar mechanisms of action. These neuromodulators inhibit the release of acetylcholine, blocking this neurotransmitter from reaching the nerve signals.
- Xeomin addresses moderate to severe upper facial lines, while Jeuveau targets moderate to severe glabellar lines.
- RealSelf users have rated Xeomin an average of 96%, while Jeuveau rated 91%, indicating high satisfaction with their results. Here are several patient reviews about these two injectables.
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Introduction to Xeomin and Jeuveau
Xeomin and Jeuveau offer unique injectable neurotoxins in aesthetic medicine to minimize the visible appearance of facial wrinkles and lines. Both injections capitalize on botulinum toxin type A as their active ingredient and have received the US Food and Drug Administration approval for cosmetic use.
While both have received the agency’s approval, this highlights that Xeomin and Jeuveau have proven their safety and efficacy in their specific indications for the facial region. Both are prescription medicines injected into muscles to temporarily improve the appearance of moderate to severe aging lines.
The comparison between Xeomin vs Jeuveau aims to differentiate their distinct formulations, common uses, benefits, and potential risks associated with their treatments. When medical professionals discuss these differences and equip patients with comprehensive information, individuals can make informed decisions for their intended treatment procedure.
Composition and Mechanism of Action
Xeomin contains the purified form of botulinum toxin type A, free from additional proteins, reducing the risk of antibody formation. This incobotulinumtoxinA ingredient distinguishes Xeomin from other neuromodulator injections in the market.
Meanwhile, Jeuveau utilizes a newer botulinum toxin type A formulation and ingredient – prabotulinumtoxinA-xvfs. The manufacturer designed this neuromodulator for aesthetic purposes and formulated it as a vacuum-dried powder for injection.
Despite the difference in their formulation and botulinum toxin type A component, Xeomin and Jeuveau offer similar mechanisms of action when injected. These neuromodulators inhibit the release of acetylcholine, blocking this neurotransmitter from reaching the nerve signals. This action leads to the temporary halting of muscle contractions, resulting in muscle relaxation and smoothing out wrinkles.
Xeomin and Jeuveau’s Common Uses
When comparing Xeomin and Jeuveau, patients must understand the difference in their approved uses from the US Food and Drug Administration. Despite the lack of approval and clinical evidence for other treatment areas, medical professionals can administer Jeuveau or Xeomin lip flip procedures with a thorough evaluation and assessment to ensure patient safety and suitability.
- Approved Uses of Xeomin: For aesthetic purposes, moderate to severe upper facial lines (frown lines, forehead lines, and crow’s feet). Approved medical conditions include chronic sialorrhea, upper limb spasticity, cervical dystonia, and blepharospasm.
- Approved Uses of Jeuveau: For aesthetic purposes, for moderate to severe frown lines between the eyebrows (glabellar lines).
Onset of Action, Duration, Dosage Units, and Cost
According to Xeomin’s FAQs, the neuromodulator can offer noticeable results as early as three to four days after injection. The first onset of action happens in less than a week, with the maximum effects occurring 30 days post-treatment. Depending on individual factors, the Xeomin effects may last approximately three months or more.
Meanwhile, Jeuveau typically takes effect within two to three days post-injection due to its use of smaller and more uniform proteins. Patients can expect the maximum number of Jeuveau results 30 days after the treatment. Furthermore, the Jeuveau injection duration of results may last up to five months, depending on various individual characteristics.
Medical professionals should know the suitable dosage for both injections based on the individual skin concerns and treatment area. However, the typical dosages of Xeomin and Jeuveau for treating glabellar lines range from 20 to 40 units. The dosage used also determines the total cost for these treatments.
The cost of Xeomin or Jeuvaeau varies based on the dosage or units used, the provider’s expertise, and geographical location. However, these products are generally similar in price, and patients can expect an average cost of $10 to $20 per unit (excluding other fees).
Clinical Studies and Patient Reviews
Patients seeking a safe and effective option for their aesthetic treatments should consult a medical professional to determine the most suitable product for their concerns, goals, and individual characteristics. Moreover, they should also look into various relevant clinical studies for Xeomin and Jeuveau to know their clinical efficacy.
Merz Aesthetic conducted clinical studies to prove the safety and efficacy of Xeomin. In two studies, 97.7% and 98.3% of patients observed significant improvements in their upper facial lines by Day 30. Moreover, two randomized, double-blind, multicenter clinical trials demonstrated that Xeomin effectively and temporarily improved the appearance of moderate to severe glabellar lines in adult patients.
A clinical study involving adult subjects with moderate to severe glabellar lines received Jeuveau injection into their frown lines. The findings demonstrated that administering a single dose of 20 units of prabotulinumtoxinA or Jeuveau effectively and safely treated glabellar lines.
Individuals should also take their time reading patient reviews of these two neuromodulators. On the online user review website for aesthetic treatments RealSelf, patients have rated Xeomin an average of 96%, while Jeuveau rated 91%, indicating high satisfaction with their results. Here are several patient reviews about these two injectables.
Conclusion
Comparing Xeomin vs Jeuveau highlights key differences in their compositions, onset of action, duration of results, and approved uses. Xeomin contains incobotulinumtoxinA, while Jeuveau uses prabotulinumtoxinA-xvfs, though both share similar mechanisms of action. Understanding these distinctions is vital for medical professionals and patients to make informed decisions about the most suitable treatment for their aesthetic needs.
Additionally, comprehensive information and evidence-based insights are crucial when discussing Xeomin and Jeuveau. This helps guide individuals toward optimal treatment procedures, ensuring safety, efficacy, and satisfaction with neuromodulator injections in aesthetic medicine.
FAQs
1. What are Xeomin and Jeuveau used for?
Xeomin is used for moderate to severe upper facial lines (frown lines, forehead lines, and crow’s feet) for aesthetic purposes, as well as for approved medical conditions such as chronic sialorrhea, upper limb spasticity, cervical dystonia, and blepharospasm. Jeuveau is used for aesthetic purposes for moderate to severe frown lines between the eyebrows (glabellar lines).
2. What is the difference in onset of action and duration between Xeomin and Jeuveau?
Xeomin typically offers noticeable results within three to four days after injection, with effects lasting approximately three months or more. Jeuveau takes effect within two to three days post-injection and may last up to five months.
3. What are the key differences in compositions between Xeomin and Jeuveau?
Xeomin contains pure botulinum toxin type A and is free from additional proteins, while Jeuveau contains botulinum toxin type A with accessory proteins. This difference in composition may impact their mechanisms of action and duration of results.
References
- 2022 Minimally Invasive Procedures. (2023). American Society of Plastic Surgeons. https://www.plasticsurgery.org/documents/News/Statistics/2022/minimally-invasive-procedure-trends-2022.pdf
- Physicians Resources – Clinical Results – Xeomin Aesthetic. (n.d.). Xeomin Aesthetic. Retrieved August 21, 2024, from https://www.xeominaesthetic.com/professionals/clinical-results
