The global demand for minimally invasive aesthetic treatments continues to rise, with over 19.1 million nonsurgical procedures performed worldwide in 2023. This trend reflects a growing preference for solutions that deliver visible, natural-looking results with reduced downtime, driven by advancements in regenerative aesthetic medicine.
Among these innovations, Plinest has emerged as a leading polynucleotide-based therapy, designed to support skin regeneration at a cellular level. Its product range—Regular, Eye, Hair, Plus, and One—offers targeted solutions for diverse aesthetic concerns, from fine lines and skin laxity to scalp vitality and post-procedural recovery.
This article will examine the distinct formulations within the Plinest product range, highlighting how each variant addresses specific skin and hair rejuvenation needs, and why they have become integral to modern aesthetic practice.
Key Takeaways
- Plinest Regular is designed for general skin rejuvenation. It stimulates collagen and elastin production, improves hydration, and addresses fine lines and uneven texture through a structured protocol involving multiple sessions.
- Plinest Eye targets the delicate periorbital area, reducing fine lines, crow’s feet, and eyelid sagging. Its gentle, low-concentration polynucleotide formulation makes it suitable for sensitive skin.
- Plinest Hair focuses on scalp health and hair follicle regeneration, improving hydration, reducing inflammation, and supporting hair growth for patients experiencing hair thinning and scalp deterioration.
- Plinest Plus offers a higher concentration of polynucleotides for deeper dermal regeneration. It is ideal for advanced signs of skin aging and patients seeking more robust tissue remodeling.
- Plinest One provides an effective yet gentle rejuvenation solution for those with mild to moderate aging concerns. It delivers visible improvements in skin tone, hydration, and texture with minimal downtime.
- The Plinest product range enables practitioners to personalize treatments based on patient needs, skin condition, and aesthetic goals, ensuring safe, effective, and natural-looking outcomes.
- Advanced polynucleotide technology underpins the efficacy of all Plinest formulations, promoting biostimulation, tissue repair, and long-term skin health without the need for invasive procedures.
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Overview of Plinest Regular for General Skin Rejuvenation
Understanding the product’s unique composition, mechanism of action, and recommended Plinest protocol is essential for achieving optimal patient outcomes. Plinest Regular offers sustainable skin revitalization with minimal downtime, making it an effective solution for concerns such as aging, dehydration, and uneven skin texture.
Derived from highly purified trout DNA, Plinest Regular stimulates fibroblast activity, encouraging the natural production of collagen and elastin while delivering deep dermal hydration. This regenerative process not only improves skin structure but also reinforces the skin barrier, leading to lasting improvements.
Key benefits of this treatment include:
- Enhanced collagen and elastin production for firmer skin
- Improved skin hydration and barrier function
- Reduction of fine lines and wrinkles over time\
- Gradual, natural-looking skin revitalization with subtle enhancements
Administration involves precise intradermal microinjections, targeting specific dermal layers for maximum efficacy. A Plinest protocol consists of several sessions spaced two to four weeks apart. This duration supports progressive rejuvenation and long-term improvements in skin quality and texture.
Targeted Treatments Using Plinest Eye for the Periorbital Area
The Plinest product range offers versatility as it can address various facial treatment areas. Particularly, Mastelli designed Plinest Eye to rejuvenate the delicate periorbital area, addressing fine lines, sagging skin, and loss of elasticity.
The Plinest product range offers tailored solutions for different facial areas, with Plinest Eye specifically designed to rejuvenate the periorbital region. This area is often prone to early signs of aging, such as fine lines, sagging skin, and loss of elasticity. Because of this, this region requires a gentle yet effective approach.
Formulated with a low-concentration polynucleotide solution (15 mg/2 mL), Mastelli’s Plinest Eye undergoes an advanced purification process to minimize irritation risks. This ensures a safe application on delicate skin while delivering visible improvements in texture, tightness, and radiance.
This treatment can deliver clinical benefits, like:
- Enhanced skin texture and radiance
- Reduction of fine wrinkles and crow’s feet
- Tightening of drooping eyelid tissues
- Minimal downtime and reduced edema risk
Treatment frequency depends on the severity of the concern and individual skin characteristics, with most patients benefiting from 3–4 sessions for optimal results. Plinest Eye offers a non-volumizing, regenerative solution for restoring a youthful appearance to this sensitive area.
Hair and Scalp Rejuvenation with Plinest Hair
Beyond facial treatments, Plinest Hair addresses scalp health and hair rejuvenation through a minimally invasive injectable therapy. It shares the regenerative properties of the Plinest range but focuses on enhancing hair follicle function and improving the overall condition of the scalp.
Plinest Hair enhances scalp hydration, reduces inflammation, and strengthens hair follicles by stimulating the extracellular matrix and supporting cellular regeneration. This leads to visibly thicker, healthier hair while mitigating hair loss caused by factors such as hormonal imbalances or environmental stressors.
Clinical benefits that patients can enjoy from this treatment are:
- Strengthening of hair follicles and reduction of hair thinning
- Improved scalp hydration and health
- Restoration of follicular function through collagen stimulation
- Enhanced protein synthesis supporting long-term hair vitality
Plinest Hair serves as an effective standalone treatment or can be combined with therapies like PRP or microneedling to amplify results, making it a versatile option for comprehensive hair rejuvenation protocols.
Enhanced Regeneration Options with Plinest Plus and Plinest One
For patients seeking more targeted regenerative solutions, Plinest Plus and Plinest One expand treatment options within the Plinest line. These formulations cater to varying levels of skin aging and patient expectations, offering flexibility in clinical applications.
Plinest Plus is formulated with a higher concentration of polynucleotides, designed to maximize fibroblast activation and accelerate collagen production. Its deeper dermal penetration addresses more advanced signs of aging, such as significant laxity and dermal thinning, delivering pronounced regenerative effects.
Plinest One, in contrast, offers a streamlined formulation tailored for individuals with mild to moderate aging concerns. It provides effective skin rejuvenation with minimal downtime, making it ideal for patients seeking subtle yet noticeable improvements in skin texture, tone, and hydration.
By diversifying its product range, Plinest allows practitioners to customize treatments based on individual patient needs, skin conditions, and desired outcomes. Customized treatment plans ensures more personalized and effective aesthetic care.
Conclusion: Selecting the Ideal Solution from the Plinest Product Range
The Plinest product range represents a significant advancement in non-surgical aesthetic treatments. These treatments offer specialized solutions for a wide spectrum of skin and hair concerns. From general skin rejuvenation with Plinest Regular to targeted periorbital care with Plinest Eye, and scalp revitalization with Plinest Hair, each product is designed to address specific clinical needs.
Further, Plinest Plus and Plinest One provide enhanced regenerative options, accommodating different levels of skin aging and patient expectations. By leveraging advanced polynucleotide technology, these formulations deliver natural-looking results with minimal downtime. Their ability to provide quick results makes the Plinest product range essential in modern aesthetic practice.
Careful product selection based on patient profile, treatment goals, and skin condition ensures safe, effective, and personalized outcomes, reinforcing Plinest’s role as a trusted solution in regenerative aesthetics.
FAQs
1. What is the main benefit of Plinest Regular?
Plinest Regular enhances skin rejuvenation by boosting collagen and elastin production. It improves hydration and texture while effectively reducing fine lines and wrinkles.
2. How does Plinest Eye specifically address concerns around the eyes?
Plinest Eye is designed for the delicate periorbital area. Its gentle formula targets fine lines and sagging skin, minimizing irritation and promoting a refreshed appearance.
3. What differentiates Plinest Plus from Plinest One?
Plinest Plus features a higher concentration of polynucleotides for deeper dermal regeneration. Meanwhile, Plinest One offers a simplified formulation ideal for those seeking effective yet subtle rejuvenation.
References
- Triana L, Palacios Huatuco RM, Campilgio G, Liscano E. Trends in Surgical and Nonsurgical Aesthetic Procedures: A 14-Year Analysis of the International Society of Aesthetic Plastic Surgery-ISAPS. Aesthetic plastic surgery. 2024;48. doi:https://doi.org/10.1007/s00266-024-04260-2
- Aesthetic medicine & Dermocosmetics – Mastelli. Mastelli. Accessed May 9, 2025. https://www.mastelli.com/therapeutic-areas/aesthetic-medicine-area
