A medical professional injecting a treatment into a patient's knee.

Zhang et al. (2015) found that a single Durolane injection is as effective as five injections of Artz. Over 90% of osteoarthritis patients responded favorably to the injections for 18 to 26 weeks. This finding underscores the effectiveness of Durolane’s single-injection therapy in delivering pain relief to patients.

Durolane stands out as a convenient and minimally invasive treatment for those with mild to moderate knee osteoarthritis (OA). Using hyaluronic acid and NASHA technology, it creates a unique formulation that provides symptomatic relief. If you’re looking to manage OA symptoms, Durolane may be the solution recommended by medical professionals.

In this article, we will focus on Durolane and its benefits for knee OA patients, considerations for being a suitable patient, and factors in reaching optimal results.

Key Takeaways

  • For individuals seeking a convenient yet effective solution, Durolane can deliver optimal results after a single injection therapy.
  • When medical professionals inject Durolane into the joint, this HA works as a lubricant and shock absorber for the joint.
  • Medical professionals typically recommend this for patients who have not found relief from other therapies or medications.
  • A patient-centric approach to Durolane therapy can align the product’s benefits with the patient’s goals through evaluation and doctor-patient engagement.
  • After the administration of the HA injectable treatment for osteoarthritis, patients should follow their trusted healthcare practitioners’ post-injection care and follow-up protocols.\
  • Durolane has shown significant potential in delivering symptomatic relief and enhancing OA patients’ overall quality of life.

Overview of Durolane and Its Mechanism of Action

Bioventus developed Durolane and its other products to deliver innovative medical devices and meet individuals’ specific needs, allowing them to live and enjoy an active lifestyle.

So, is Durolane a one time injection? For individuals seeking a convenient yet effective solution, Durolane can deliver optimal results after a single injection therapy. Providers have used hyaluronic acid injections for knee OA worldwide, improving the lives of many individuals. The Food and Drug Administration approved Durolane as a treatment for patients when oral medications or other therapies have failed to respond.

When does Durolane work? This injection for OA utilizes the potency of hyaluronic acid, allowing it to work and relieve pain immediately. HA is a natural substance found in the body, specifically in the eyes, skin, and joints.

When medical professionals inject Durolane into the joint, this HA works as a lubricant and shock absorber. It facilitates smooth movement and provides pain-free action to OA patients.

When injected into the affected joint, Durolane aims to restore the viscoelasticity of the synovial fluid. This benefits people dealing with osteoarthritis, where the quality and quantity of synovial fluid get compromised over time. Bioventus uses NASHA for Durolane injections to naturally entangle the HA chains, creating a gel bead-like structure. This can offer longer-lasting effects on individuals. 

So, how long does Durolane last? The treatment injection typically lasts about six (6) months or longer. Durolane’s unique formulation is a factor in its longevity. Aside from this, Durolane also offers various benefits for joint health and OA treatment.

  • Pain Relief: Durolane can reduce the symptomatic joint pain caused by osteoarthritis.
  • Improved Physical Activity: OA patients can feel better and have pain-free physical movement after a Durolane injection.
  • Single Injection: Durolane requires a single injection to provide symptomatic relief for OA patients compared to other viscosupplementation products.
  • Enhanced Quality of Life: Durolane enhances the quality of life of individuals with OA by providing pain relief and improved joint mobility.

While medical professionals consider Durolane safe for most individuals, it’s best to consult with them to determine whether this single-injection therapy suits you. Their expertise can explain how the treatment works, the potential risks and complications, and how Durolane can offer these benefits.

Patient Selection and Assessment for Durolane Treatment

A medical professional examining the knee of the patient.

When considering Durolane treatment for your osteoarthritis concerns, it’s crucial to identify the factors that may affect the outcomes. Visit your trusted healthcare providers for a thorough consultation about Durolane injections and learn their insights about the therapy. Their advice may help you make informed decisions about your healthcare treatment.

To determine whether you are a suitable candidate for a Durolane injection, a consultation with an expert may offer more information about the treatment. Medical professionals typically recommend this for patients who have not found relief from other therapies or medications. Moreover, a few warnings may prevent patients from receiving Durolane injections.

  • Patients with active skin disease or infection at or near the injection site.
  • Patients who have hypersensitivity or allergy to hyaluronic acid-based products.
  • The Durolane manufacturer has not tested this treatment on pregnant or lactating women or children (21 years and younger).

Assess the severity of the patient’s condition before proceeding with Durolane treatment. Medical professionals may evaluate the condition through various clinical examinations and imaging tests. Several symptoms may also occur that lead to knee OA.

  • Sore Joint
  • Joint Stiffness
  • Pain when Moving your Joint
  • Pain when doing Everyday Activities such as Climbing Stairs, Getting up from a Chair, or Buttoning a Shirt
  • Joint Pain
  • Grating or Catching Sensation when Moving your Joint
  • Deterioration of Coordination or Grip Strength
  • Weakened Muscular Strength

Furthermore, every patient is unique, and the treatment plans should also be. A patient-centric approach to Durolane therapy can align the product’s benefits with the patient’s goals through evaluation and doctor-patient engagement. Clear communication between the provider and the patient allows both parties to create a compelling and safe tailored treatment plan.

This approach significantly enhances the positive impact of this single-injection therapy on patients suffering from OA. While tailoring the treatment plan, medical practitioners may ask multiple questions about the patient’s medical history, primary concerns, overall health condition, and lifestyle. This allows them to create a Durolane treatment plan that offers maximum outcomes without compromising the patient’s health.

Injection Technique and Site Selection for Durolane Administration

The administration of Durolane involves a meticulous process that requires an expert’s precision and expertise. Seeking a trusted and experienced medical provider can help patients achieve their pain relief goals from lifelong joint disease. Moreover, they can also address the maintenance of Durolane so that individuals can continuously increase their quality of life.

Proper administration of Durolane is a significant factor in achieving optimal outcomes. When injected, Durolane restores the physiological viscoelasticity of the affected joint’s synovial fluid. This makes the administration essential, as wrong placement and injection technique may lead to less effective pain relief or adverse reactions.

Licensed physicians and medical professionals should only inject Durolane into the patient’s affected joints, as they know how to administer it per local legislation. They will follow the tailored treatment plan to avoid complications and risks to the patient’s health. During the treatment day, providers must swab the injection site with a suitable antiseptic solution before injection.

Depending on the treatment area, these medical professionals will utilize the recommended needle with the appropriate length. It’s worth noting that they should remove joint effusion before injecting Durolane into the affected joint. Choose a route for an intra-articular injection to avoid damaging other vital structures.

Lastly, precision in the delivery and distribution of the Durolane medication is critical to its potent effectiveness. Medical professionals should administer this single injection directly into the specific joint. Fluoroscopic control or ultrasound imaging may help deliver the injection to the precise location of the needle.

Adjunctive Therapies and Rehabilitation Exercises to Enhance Durolane Treatment

After a Durolane treatment, OA patients can feel positive results two days after the injection session. About two weeks later, they will have noticed the optimal outcome of Durolane injections. Medical professionals can guide Durolane-treated patients to maximize its effectiveness.

  • Complementary Therapies: These therapies can enhance the Durolane treatment’s efficiency and provide additional health benefits, such as pain relief, reduced anxiety and stress, and improved mood. Examples include massage, meditation, and music therapy; each type may target specific health aspects. Incorporating these therapies can enhance the overall efficacy of Durolane injections.
  • Incorporating Physical Therapy and Low-Impact Exercises: Physical therapy and low-impact exercises can help manage osteoarthritis by improving joint strength, mobility, flexibility, and overall health. These exercises can also improve bone density and muscle strength and enhance the effectiveness of the Durolane treatment. Trusted providers may add exercises like squats, jogging, and bicep curls to the treatment plan.
  • Lifestyle Modifications: Other factors influencing joint health and mobility include maintaining a healthy weight, eating a balanced diet, and avoiding strenuous activities that may affect the joint. Moreover, regular exercise and physical activity can preserve the Durolane treatment effects’ on joint flexibility and muscle strength.

Post-Injection Care and Follow-Up Protocols for Durolane Treatment

A consultation between a doctor and a patient.

After the administration of the HA injectable treatment for osteoarthritis, patients should follow their trusted healthcare practitioners’ post-injection care and follow-up protocols. These factors can offer optimal results and sustained symptomatic relief.

  • Importance of Monitoring Patient Progress: Regular follow-up appointments allow medical professionals to assess the patient’s response to the treatment. They can adjust the treatment plan if necessary and may detect risks or complications early. This monitoring process can help optimize the results and provide better joint health and quality of life.
  • Addressing Concerns or Complications Promptly: Assess and address any concerns or complications immediately following the Durolane treatment. If common side effects like pain, swelling, or redness in the injection site persist, it’s best to visit your trusted provider. Moreover, promptly report any infections or allergic reactions.
  • Optimizing Durolane’s Effectiveness: Patients can maximize the benefits of the Durolane treatment through follow-up care. This includes following the healthcare provider’s post-treatment instructions and adopting a healthier lifestyle to enhance joint health and functional mobility.

Summary and Practical Tips for Healthcare Professionals

Durolane treatment offers a comprehensive approach to managing knee osteoarthritis among patients. Its maximum effectiveness lies in its unique formulation and mechanism of action, careful patient selection, precise administration, and regular follow-up care. Durolane has shown significant potential in delivering symptomatic relief and enhancing OA patients’ overall quality of life.

For healthcare professionals, it’s critical to implement strategies that maximize the effectiveness of Durolane treatment. This includes understanding the patient’s condition, customizing a treatment plan, and incorporating therapies and exercises.

Regular monitoring and prompt addressing of concerns or complications can also help. With these tips, healthcare professionals can enhance the outcomes of Durolane treatment for their OA patients.

About: Medica Depot is your trusted all-in-one supplier, offering a range of high-quality medical injectables and supplies. We offer a worry-free experience in searching for the best and most popular products on the market, like Durolane. Whether for health professionals, plastic surgeons, dermatologists, licensed estheticians, or other specialists, we can offer genuine, brand-name products you may need. With Medica Depot, we prioritize serving you better to improve the patient’s quality of life.

References

  1. Zhang, H., Zhang, K.-K., Zhang, X., Zhu, Z., Yan, S., Sun, T., Ai, G., Jones, J. T., R. Grant Steen, Shu, B., Zhang, J., & Lin, J. (2015). Comparison of two hyaluronic acid formulations for safety and efficacy (CHASE) study in knee osteoarthritis: a multicenter, randomized, double-masked, 26-week non-inferiority trial comparing Durolane to Artz. Arthritis Research & Therapy, 17(1). https://doi.org/10.1186/s13075-015-0557-x
  2. DUROLANE. (n.d.). Bioventus OA Knee Pain Relief. Retrieved March 27, 2024, from https://durolane.com/en/durolane/faq/