A medical professional administering a knee injection into the patient's joint.

Carney et al. (2021) conducted a six-year cohort study, showing that repeated Durolane injections provided long-term relief. Patients experienced less pain for about 15 months after the initial treatment and subsequent injections. This underscores the safety and effectiveness of Durolane hyaluronic acid injections for knee osteoarthritis patients.

Knee osteoarthritis typically takes time to develop and tends to get worse. It brings symptoms like joint pain, swelling, and stiffness in the affected area. For those seeking an alternative to surgery, Durolane provides a solution. This injection treatment offers optimal outcomes and can enhance individuals’ quality of life.

This article will focus on Durolane’s effectiveness for knee osteoarthritis, its long-lasting effects, and medical professionals’ insights about this single-injection therapy.

Key Takeaways

  • The Durolane manufacturer created this hyaluronic acid gel-like substance, which medical professionals inject into the joint and acts as a lubricant and shock absorber for the joints.
  • The injection can effectively replenish joint fluid, allowing Durolane to provide symptomatic relief and may delay surgery.
  • Thanks to the gel bead-like HA in the formulation, it can slow down the progression of osteoarthritis and delay or avoid the need for replacement surgery.
  • Durolane has proven its efficacy and safety while demonstrating how it can enhance patients’ quality of life. 
  • This injection considerably enhanced the quality of life of Durolane-treated people as early as two weeks after the treatment. 
  • A patient-centric approach comprehensively addresses one’s overall health instead of targeting the knee OA symptoms alone. 

Understanding Durolane Treatment for Osteoarthritis

Durolane is a single-injection therapy developed by Bioventus, LLC. This treatment for knee osteoarthritis directly targets the symptoms of the degenerative joint disease. The Durolane manufacturer created this hyaluronic acid gel-like substance, which medical professionals inject into the joint. The HA in the injection works as the fluid that surrounds the joints in the body, in this case, the knee.

When injected, the fluid acts as a lubricant and shock absorber for the joints. The Durolane ingredients created a unique formulation and non-animal stabilized hyaluronic acid (NASHA) technology that stands out among others. NASHA technology naturally entangles HA chains, creating a gel bead-like structure in the injections.

The HA structure in the Durolane injections slows the degradation, allowing the treatment and its effect to have an extended duration. So, how long for Durolane to work? The infusion can effectively replenish joint fluid, allowing Durolane to provide symptomatic relief and may delay surgery.

Patients need to know what Durolane treatments can offer to them. Medical professionals can recommend Durolane to individuals seeking relief from the symptoms of osteoarthritis.

  • Pain Relief: Durolane’s formulation and technology allow it to provide up to six (6) months of relief to individuals. Depending on the severity of the OA condition, some treatment effects may last longer.
  • Reduced Medications: Durolane has shown efficacy in treating OA symptoms, significantly reducing the need for oral or other pain medications. This can benefit patients who may have experienced side effects from other medicines.
  • Avoid or Delay Surgery: With regular Durolane treatment, depending on your professional’s recommendations, the injection treatment can avoid or postpone invasive therapies. Durolane maintenance can benefit individuals who wish to prevent replacement surgery.
  • Versatility: Durolane effectively treated OA symptoms in various joints, such as the knee, shoulder, ankle, fingers, and toes. With the help of professional expertise, individuals can maximize the benefits of Durolane for their joint disease concerns.

Immediate Symptom Relief vs. Long-Term Joint Health

The knee joint of an individual.

Among hyaluronic acid injections that treat osteoarthritis, Durolane is the top choice for medical practitioners and their patients suffering from OA. When learning a new treatment, patients must know what benefits and relief it offers.

Short-Term Effects of Durolane

  • Immediate Relief: Durolane can provide relief outcomes to patients by lubricating and cushioning the affected joint area. Typically, patients notice results two days after the treatment and can fully acquire optimal relief outcomes in about two weeks.
  • Pain Reduction: Tied to immediate relief, it reduces the pain and increases joint function and mobility. It can quickly improve the patient’s quality of life after the injection treatment,
  • Side Effects: Like other treatments, patients may experience mild to moderate side effects after the injection. These include discomfort, swelling, pain, or mild reactions at the injection site.

Long-Term Impact on Joint Health

Durolane injections can stimulate the production of hyaluronic acid, improving the joint cartilage’s strength. Thanks to the gel bead-like HA in the formulation, it can slow down the progression of osteoarthritis and delay or avoid the need for replacement surgery.

According to an observational study, individuals with grades 2 to 3 osteoarthritis can experience longer-lasting effects after the injection treatment. Pain relief with subsequent Durolane injections can extend the duration to an average of 466 days. This emphasizes Durolane’s capability to have a lasting impact on joint health.

Durolane proved its treatment effect to last up to six months of relief for patients. A single injection can provide long-term symptomatic relief; repeated administration can maintain this effect. This hyaluronic acid injection into the knee can offer immediate and prolonged benefits for joint health.

It’s worth noting that patients can only achieve optimal outcomes under healthcare professionals’ guidance. They understand best about the treatment and can create a tailored treatment plan for each patient, considering their medical history, concerns, and goals. This ensures that Durolane therapies can lead to safe and practical sessions.

Durolane’s Enduring Effects on Joint Mobility

  • Improving Joint Function: A single Durolane injection can work as a lubricant and shock absorber for an extended period. As it restores the HA balance in the joint, it can significantly reduce joint pain and improve its function.
  • Enhancing Range of Motion: Durolane can improve the range of motion in the affected joints. Individuals can improve their joint function and mobility and address common OA symptoms such as pain, stiffness, and swelling.
  • Impact on Daily Activities and Quality of Life: The symptomatic relief brought by the Durolane injection tremendously affects the daily lives of patients suffering from osteoarthritis. Moreover, pain relief and improved mobility allow individuals to return to their routine without discomfort.

Durolane has proven its efficacy and safety while demonstrating how it can enhance patients’ quality of life. Many Durolane patients have shared their positive experiences after receiving Durolane injections. In just two weeks, they regained control of their knee without feeling pain or swelling on the site.

Expert Insights

Many medical professionals and experts have conducted studies about Durolane, its benefits, and the effectiveness of the injections. According to an open-label study, most individuals have proven viscosupplementation using NASHA technology effective and well-tolerated. The results revealed consistency with knee and hip OA, showing favorable tolerability and an extended duration.

Moreover, Leighton R. et al. (2018) also shared that the evidence from clinical studies demonstrated sustained and effective relief of knee OA symptoms. The treatment with NASHA injections also showed safe procedures beneficial for managing knee OA.

Durolane has also revealed its product’s science-driven results, comparing it to Synvisc-One. A Level 1 study showed that Durolane offered a more significant reduction in pain scores at three (3) and six (6) months. It also exhibited that Durolane injection is clinically equivalent to five-injection hyaluronic acid therapy.

79% of the patients treated with Durolane experienced improved pain after their treatment, lasting until 26 weeks. This study emphasized Durolane’s convenience factor after its single-injection therapy. Furthermore, this injection considerably enhanced the quality of life of Durolane-treated people as early as two weeks after the treatment. Durolane can extend the optimal outcome until 24 weeks for symptomatic relief.

Making Informed Decisions

An individual consulting with a medical professional.

A thorough consultation with a medical professional can help patients understand more about the procedure and how it can align with their needs, goals, and concerns. Medical professionals may inquire about the factors to consider before Durolane treatment, which they can add to the customized treatment plan.

  • Allergies: Patients should inform their doctors about unusual or allergic reactions to other medicines. Individuals with hypersensitivity or allergy to any HA solution should not undergo a Durolane injection.
  • Age: The effects of Durolane injections have yet to be thoroughly studied and tested for younger people aged 21 and below.
  • Other Medical Conditions: Medical professionals should use this single-injection therapy with caution on patients with pre-existing chondrocalcinosis as the treatment may lead to an acute attack. Moreover, patients should inform their doctors of other medical conditions to ensure a safe procedure.
  • Pregnancy or Breastfeeding: Like younger individuals, the Durolane manufacturer has not tested the injection in pregnant and lactating individuals.
  • Medicine and Food Intakes: It’s crucial to consider potential risks with other medications or food and beverages. It’s necessary to let the providers know about your interactions with any of these intakes.

A patient-centric approach considers the patient’s needs, goals, treatment, and affordability. It comprehensively addresses one’s overall health instead of targeting the knee OA symptoms alone. With this, doctors play a significant role in engaging patients in creating tailored treatment plans to ensure their safety and offer them the knowledge to make informed decisions for their healthcare.

Healthcare providers can offer their expertise to patients so that they can understand how the treatment works, Durolane’s longer-lasting results and benefits, and its versatility in addressing this degenerative joint disease. Patient education is a powerful tool for empowering patients to take control of their health.

Conclusion

Durolane’s long-term impact on joint health offers a promising lifestyle, delivering immediate symptom relief and sustained benefits. This single-injection treatment can enhance joint function, improve range of motion, and positively impact a patient’s daily activities and quality of life. Healthcare providers can deliver these results to individuals with a patient-centric approach and a tailored treatment plan.

Medical professionals may find encouraging individuals to sustain joint health practices crucial. However, they can utilize the power of Durolane to empower patients to take control of their joint health and overall health to foster patient engagement. Durolane’s role in joint care looks likely to expand, offering hope for many patients dealing with osteoarthritis.

About: Medica Depot is your trusted all-in-one supplier, offering a range of high-quality medical injectables and supplies. We offer a worry-free experience in searching for the best and most popular products on the market, like Durolane. Whether for health professionals, plastic surgeons, dermatologists, licensed estheticians, or other specialists, we can offer genuine, brand-name products you may need. With Medica Depot, we prioritize serving you better to improve the patient’s quality of life.

References

  1. Carney, G., Harrison, A., & Fitzpatrick, J. (2021). Long-Term Outcome Measures of Repeated Non-Animal Stabilized Hyaluronic Acid (Durolane) Injections in Osteoarthritis: A 6-Year Cohort Study with 623 Consecutive Patients. Open access rheumatology: research and reviews, 13, 285–292. https://doi.org/10.2147/OARRR.S331562
  2. Science-driven results. (n.d.). Bioventus OA Knee Pain Relief. Retrieved March 26, 2024, from https://www.oakneepainrelief.com/durolane/science-driven-results/