STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine
$109.00
Manufacturer: Vivacy
Active Substance(s) : CROSS-LINKED HYALURONIC ACID (HA), MANNITOL, LIDOCAINE
Strength: 18.5mg/g HA, 3mg/ml Lidocaine
Pack Size: 1 x 1ml Pre-Filled Syringes, 2 x 30 G ½ Needles
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is an injectable hyaluronic acid lips filler (18.5mg/g cross-linked HA with 0.3% lidocaine, stabilized with mannitol) from Laboratories VIVACY, France, designed for precise lip augmentation and perioral volume restoration. As the successor to STYLAGE® SPECIAL LIPS (Bi-SOFT®), it uses IPN-Like Technology™ and the updated BI-FLEX® syringe for improved ergonomics and injection control, and is supplied as 1 × 1mL prefilled syringe with 2 × 30G ½ needles in the new magenta/purple and white packaging. Licensed professionals looking to buy STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine online should verify local regulatory requirements before procurement and contact Medica Depot’s support representatives for information and guidance.
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INFORMATION
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine — Injectable HA Lips Filler for Precise Lip Augmentation & Perioral Volume Restoration
Product Specifications
- Drug Class: Injectable hyaluronic acid filler for lip augmentation (cross-linked, BI-FLEX® syringe system, with lidocaine)
- Active Ingredients: Hyaluronic acid (cross-linked) 18.5mg/g; Lidocaine 0.3%
- Manufacturer: Laboratories VIVACY
- Brand: STYLAGE®
- Country of Origin: France
- Strength:5mg/g HA; 0.3% Lidocaine
- Dosage Form: Injectable gel — 1 × 1mL prefilled BI-FLEX® syringe + 2 × 30G ½ needles
- FDA Status: Not currently approved by the US FDA
- Regulatory Status: CE-marked (EU); current as of 2026
Mechanism of Action of STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine Injection
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine injection contains cross-linked HA that integrates into lip and perioral tissues, binding water to restore volume, define borders, and improve hydration at the injection site. This allows targeted correction of localized volume loss and fine lines in a dynamic area such as the lips.
IPN-Like Technology™ combines two interpenetrating HA networks, increasing gel cohesivity, elasticity, and resistance to mechanical deformation compared with single-network fillers. The gel remains stable with lip movement yet is soft to the touch, while 0.3% lidocaine reduces injection discomfort without requiring a separate injectable anesthetic in most patients.
Like STYLAGE® M and L, this formulation incorporates mannitol to act as an antioxidant scavenger, minimizing post-injection swelling and preventing premature free-radical degradation in the highly mobile lip tissue. The product is gradually degraded by endogenous enzymes and can be reversed with hyaluronidase if required.
About STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine replaces the former STYLAGE® SPECIAL LIPS Bi-SOFT® while retaining the same lip-specific HA concentration and lidocaine content. The BI-FLEX® syringe was introduced to improve ergonomics, reduce extrusion force, and enhance precision for safer, more controlled injections in delicate lip tissue. The updated magenta/purple and white packaging differentiates this lips filler from earlier presentations and other STYLAGE® products, assisting procurement teams and practitioners when re-ordering.
The formulation utilizes VIVACY’s signature mannitol stabilization, aligning its preservation profile with the rest of the classic line, while its specific 18.5mg/g HA concentration delivers the precise rheology required for delicate mucosal tissue rather than deep-plane structural lifting
Practitioners evaluating whether STYLAGE® is a good filler for lip indications will find the answer in its formulation choices:
- IPN-Like Technology™ for structural integrity under lip movement
- Lip-optimized BI-FLEX® rheological profile
- Built-in lidocaine for patient comfort
As a CE-marked product from an established manufacturer, it meets the quality standards expected of professional injectable dermal fillers in aesthetic medicine.
Indications & Clinical Use
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is indicated for lip augmentation, including subtle to moderate volume enhancement, contour refinement, and correction of age-related volume loss in the lips treatment area. It can help balance upper- and lower-lip proportions and refine the cupid’s bow when used by trained practitioners.
Perioral indications include vermillion border definition, shaping of the philtrum columns, and softening of selected perioral lines with appropriate micro-bolus or linear threading techniques. SPECIAL LIPS rheology supports precision shaping and definition, and can supplement higher-volume fillers used elsewhere in multi-layer lip protocols.
Patient selection should consider lip tissue thickness, skin condition, and the desired correction outcome. The product is for licensed aesthetic medicine professionals only; practitioners must screen for contraindications, follow aseptic technique, and avoid intravascular injection.
Administration, Side Effects & Safety
Injection sites typically include the lip body, vermillion border, and philtrum, with depth and pattern tailored to anatomy and practitioner technique. The BI-FLEX® syringe aids controlled extrusion and precise placement in small, anatomically complex zones.
Lidocaine 0.3% provides intraprocedural analgesia during lidocaine administration, while a topical anesthetic can be added based on patient sensitivity. After treatment, patients should be advised to avoid excessive sun exposure, heat, and strenuous exercise until redness and swelling resolve.
Common side effects include temporary redness, swelling, tenderness, and bruising, which typically resolve within a few days. Serious but rare complications include infection, nodules, vascular occlusion, skin necrosis, and visual disturbance, requiring prompt management by trained professionals familiar with filler complication and hyaluronidase protocols.
Legal & Regulatory Status for STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is CE-marked and manufactured in France by Laboratories VIVACY for professional aesthetic use in the EU and other CE-recognizing markets. It is not currently approved by the US FDA. Use is restricted to licensed medical professionals and registered aesthetic clinics. Practitioners should verify local regulatory status and any applicable import rules before ordering or administering this Stylage filler. Information on this page is current as of 2026 and is subject to change.
When buying online, practitioners should source exclusively from verified, authorized distributors who can provide documentation of product authenticity and supply chain compliance. Practitioners wishing to buy STYLAGE® or buy dermal fillers through an authorized channel should confirm product authenticity and documentation with their chosen distributor. For sourcing guidance and information, contact Medica Depot’s support representatives.
Citations
- Kaufman-Janette J, Taylor SC, Cox SE, et al. Efficacy and safety of a new resilient hyaluronic acid dermal filler, in the correction of moderate-to-severe nasolabial folds: a 64-week, prospective, multicenter, controlled, randomized, double-blind and within-subject study. J Cosmet Dermatol. 2019;18(5):1244-1253. doi: 10.1111/jocd.13101
- Sundaram H, Cassuto D. Biophysical characteristics of hyaluronic acid soft-tissue fillers and their relevance to aesthetic applications. Plast Reconstr Surg. 2013;132(4 suppl 2):5S-21S. doi: 10.1097/PRS.0b013e31829c4edf
- Guo J, Fang W, Wang F. Injectable fillers: current status, physicochemical properties, function mechanism, and perspectives. RSC Adv. 2023;13(34):23841-23858. doi: 10.1039/d3ra04321e
The contents of this page are meant for licensed medical professionals. They serve informational purposes only and are not to be taken as medical advice.
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine — Injectable HA Lips Filler for Precise Lip Augmentation & Perioral Volume Restoration
Product Specifications
- Drug Class: Injectable hyaluronic acid filler for lip augmentation (cross-linked, BI-FLEX® syringe system, with lidocaine)
- Active Ingredients: Hyaluronic acid (cross-linked) 18.5mg/g; Lidocaine 0.3%
- Manufacturer: Laboratories VIVACY
- Brand: STYLAGE®
- Country of Origin: France
- Strength:5mg/g HA; 0.3% Lidocaine
- Dosage Form: Injectable gel — 1 × 1mL prefilled BI-FLEX® syringe + 2 × 30G ½ needles
- FDA Status: Not currently approved by the US FDA
- Regulatory Status: CE-marked (EU); current as of 2026
Mechanism of Action of STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine Injection
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine injection contains cross-linked HA that integrates into lip and perioral tissues, binding water to restore volume, define borders, and improve hydration at the injection site. This allows targeted correction of localized volume loss and fine lines in a dynamic area such as the lips.
IPN-Like Technology™ combines two interpenetrating HA networks, increasing gel cohesivity, elasticity, and resistance to mechanical deformation compared with single-network fillers. The gel remains stable with lip movement yet is soft to the touch, while 0.3% lidocaine reduces injection discomfort without requiring a separate injectable anesthetic in most patients.
Like STYLAGE® M and L, this formulation incorporates mannitol to act as an antioxidant scavenger, minimizing post-injection swelling and preventing premature free-radical degradation in the highly mobile lip tissue. The product is gradually degraded by endogenous enzymes and can be reversed with hyaluronidase if required.
About STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine replaces the former STYLAGE® SPECIAL LIPS Bi-SOFT® while retaining the same lip-specific HA concentration and lidocaine content. The BI-FLEX® syringe was introduced to improve ergonomics, reduce extrusion force, and enhance precision for safer, more controlled injections in delicate lip tissue. The updated magenta/purple and white packaging differentiates this lips filler from earlier presentations and other STYLAGE® products, assisting procurement teams and practitioners when re-ordering.
The formulation utilizes VIVACY’s signature mannitol stabilization, aligning its preservation profile with the rest of the classic line, while its specific 18.5mg/g HA concentration delivers the precise rheology required for delicate mucosal tissue rather than deep-plane structural lifting
Practitioners evaluating whether STYLAGE® is a good filler for lip indications will find the answer in its formulation choices:
- IPN-Like Technology™ for structural integrity under lip movement
- Lip-optimized BI-FLEX® rheological profile
- Built-in lidocaine for patient comfort
As a CE-marked product from an established manufacturer, it meets the quality standards expected of professional injectable dermal fillers in aesthetic medicine.
Indications & Clinical Use
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is indicated for lip augmentation, including subtle to moderate volume enhancement, contour refinement, and correction of age-related volume loss in the lips treatment area. It can help balance upper- and lower-lip proportions and refine the cupid’s bow when used by trained practitioners.
Perioral indications include vermillion border definition, shaping of the philtrum columns, and softening of selected perioral lines with appropriate micro-bolus or linear threading techniques. SPECIAL LIPS rheology supports precision shaping and definition, and can supplement higher-volume fillers used elsewhere in multi-layer lip protocols.
Patient selection should consider lip tissue thickness, skin condition, and the desired correction outcome. The product is for licensed aesthetic medicine professionals only; practitioners must screen for contraindications, follow aseptic technique, and avoid intravascular injection.
Administration, Side Effects & Safety
Injection sites typically include the lip body, vermillion border, and philtrum, with depth and pattern tailored to anatomy and practitioner technique. The BI-FLEX® syringe aids controlled extrusion and precise placement in small, anatomically complex zones.
Lidocaine 0.3% provides intraprocedural analgesia during lidocaine administration, while a topical anesthetic can be added based on patient sensitivity. After treatment, patients should be advised to avoid excessive sun exposure, heat, and strenuous exercise until redness and swelling resolve.
Common side effects include temporary redness, swelling, tenderness, and bruising, which typically resolve within a few days. Serious but rare complications include infection, nodules, vascular occlusion, skin necrosis, and visual disturbance, requiring prompt management by trained professionals familiar with filler complication and hyaluronidase protocols.
Legal & Regulatory Status for STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is CE-marked and manufactured in France by Laboratories VIVACY for professional aesthetic use in the EU and other CE-recognizing markets. It is not currently approved by the US FDA. Use is restricted to licensed medical professionals and registered aesthetic clinics. Practitioners should verify local regulatory status and any applicable import rules before ordering or administering this Stylage filler. Information on this page is current as of 2026 and is subject to change.
When buying online, practitioners should source exclusively from verified, authorized distributors who can provide documentation of product authenticity and supply chain compliance. Practitioners wishing to buy STYLAGE® or buy dermal fillers through an authorized channel should confirm product authenticity and documentation with their chosen distributor. For sourcing guidance and information, contact Medica Depot’s support representatives.
Citations
- Kaufman-Janette J, Taylor SC, Cox SE, et al. Efficacy and safety of a new resilient hyaluronic acid dermal filler, in the correction of moderate-to-severe nasolabial folds: a 64-week, prospective, multicenter, controlled, randomized, double-blind and within-subject study. J Cosmet Dermatol. 2019;18(5):1244-1253. doi: 10.1111/jocd.13101
- Sundaram H, Cassuto D. Biophysical characteristics of hyaluronic acid soft-tissue fillers and their relevance to aesthetic applications. Plast Reconstr Surg. 2013;132(4 suppl 2):5S-21S. doi: 10.1097/PRS.0b013e31829c4edf
- Guo J, Fang W, Wang F. Injectable fillers: current status, physicochemical properties, function mechanism, and perspectives. RSC Adv. 2023;13(34):23841-23858. doi: 10.1039/d3ra04321e
The contents of this page are meant for licensed medical professionals. They serve informational purposes only and are not to be taken as medical advice.
Frequently Asked Questions
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is a CE-marked, lip-dedicated hyaluronic acid filler (18.5mg/g) with 0.3% lidocaine, manufactured by Laboratories VIVACY in France. It uses IPN-Like Technology™ and the BI-FLEX® syringe system for precise lip augmentation and perioral volume restoration. It is supplied as a 1 × 1mL prefilled syringe with 2 × 30G ½ needles and is for licensed aesthetic professionals only.
The cross-linked HA gel integrates into lip tissue and binds water, restoring volume, definition, and hydration while smoothing selected perioral lines. IPN-Like Technology™ provides a cohesive, elastic matrix that resists deformation during lip movement, and 0.3% lidocaine reduces injection discomfort without requiring a separate injectable anesthetic in most patients.
It is indicated for lip augmentation (e.g., volume enhancement, contour refinement, and correction of age-related volume loss)and for defining the vermillion border and philtrum columns. Selected perioral lines can also be treated when injected by trained professionals in aesthetic medicine.
It was previously marketed as STYLAGE® SPECIAL LIPS with the Bi-SOFT® syringe system. The BI-FLEX® rebrand introduced an updated syringe for improved ergonomics and injection precision, along with the new magenta/purple and white packaging for easier product identification.
Duration varies by factors such as skin type, treatment area, technique, and lifestyle habits.
STYLAGE® dermal fillers, including STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine, are CE-marked in Europe but are not currently approved by the US FDA. Practitioners outside the EU should verify the regulatory status of this Stylage filler in their jurisdiction before ordering or administering it. Information is current as of 2026.
Whether STYLAGE® is a good filler depends on the indication, technique, and patient selection, but it is widely used internationally and benefits from IPN-Like Technology™ and CE-marked manufacturing standards. STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is formulated specifically for the lips, with a lip-adapted rheological profile and BI-FLEX® precision syringe for controlled, natural-looking results.
Common side effects include temporary swelling, redness, tenderness, and bruising at the injection site, which typically resolve within a few days and are consistent with other injectable dermal fillers. Rare but serious complications (vascular occlusion, skin necrosis, or visual disturbance) require immediate management by a trained medical professional familiar with hyaluronidase protocols.




