MEDITOXIN® 200u

MEDITOXIN® 200u Key Features and Benefits

MEDITOXIN® 200u is a botulinum toxin type A complex designed for medical and cosmetic purposes. It offers proven efficacy and safety, verified through comparative clinical studies against leading alternatives like OnabotulinumtoxinA. The product is distributed worldwide under various brand names, including Siax®, Botulift®, Cunox®, and Neuronox®. Key advantages include:

• Comparable efficacy and safety to OnabotulinumtoxinA in multiple clinical indications.
• A versatile product line available in 50, 100, and 200 units for tailored use.
• Trusted globally in 27 countries, with registrations ongoing in an additional 30 nations.

MEDITOXIN® 200u Reconstitution Chart

Dilution Guidelines: MEDITOXIN® 200u is supplied as a lyophilized white powder. It is reconstituted with 0.9% sodium chloride injection to achieve the desired dosage.

Preparation Steps:

1. Inject the appropriate volume of diluent gently into the vial.
2. Mix by rotating; do not shake.
3. Use within 24 hours after reconstitution, stored at 2–8°C.

MEDITOXIN® 200u Storage Information

• Store unopened vials in a freezer (below -5°C) or refrigerator (2–8°C).
• Reconstituted product must be stored in the refrigerator and used within 24 hours.
• Inspect for clarity and colorlessness before use. Discard if particulate matter is present.

MEDITOXIN® 200u Product Treatment Areas

Meditoxin acts on the cause of wrinkles by targeting the underlying muscle activity responsible for their formation. As an immunobiological drug with a muscle relaxant effect, it is widely used in both aesthetic and therapeutic treatments. The following are key indications for its use:

• Glabellar Wrinkles: Temporary improvement of moderate to severe frown lines caused by corrugator and procerus muscle activity. This helps smooth the skin for a more youthful appearance.
• Blepharospasm: Effective treatment for patients aged 18 and older experiencing involuntary eyelid muscle contractions.
• Cerebral Palsy: Helps correct equinus foot deformity in pediatric patients (ages 2 and older), improving mobility and comfort.
• Muscle Spasticity: Manages upper limb spasticity in post-stroke patients (ages 20 and older) by reducing muscle stiffness and improving movement.

By addressing both cosmetic and medical concerns, Meditoxin provides a versatile solution for patients seeking improved skin aesthetics and muscle function.

MEDITOXIN® 200u Dosing for Different Indications

• Glabellar Wrinkles:
  • Dosage: 20 units divided into 5 injection sites (4 units per site).
  • Injection depth: Subcutaneous, avoiding the levator palpebrae superioris.
  • Duration of effect: 3–4 months.
• Blepharospasm:
  • Initial dose: 1.25–2.5 units per site.
  • Sites: Medial and lateral pre-tarsal orbicularis oculi.
  • Maximum dose: 200 units in a 30-day period.
• Pediatric Cerebral Palsy:
  • Dosage: 4 units/kg for hemiplegia, 6 units/kg for diplegia (max: 200 units per session).
  • Injection: Medial and lateral gastrocnemius muscle heads.
• Upper Limb Spasticity:
  • Dosage tailored based on muscle size and spasticity severity.
  • Recommended total dose: Not exceeding 360 units.

MEDITOXIN® 200u Side Effects and Precautions

Common Side Effects:

• Eyelid ptosis (3.2% incidence).
• Extraocular muscle disorders (<1%).

Precautions:

• Avoid frequent injections (<12 weeks apart) to minimize tolerance.
• Reconstituted product must not be reused across multiple patients.
• Ensure accurate dose measurement to prevent adverse reactions like ptosis.

MEDITOXIN® 200u Aftercare

Patients should adhere to the following aftercare guidelines:

• Avoid applying makeup for 24 hours post-injection.
• Minimize exposure to UV light or extreme temperatures for 48 hours.
• Refrain from vigorous physical activity on the day of treatment.

MEDITOXIN® 200u Drug Interactions

MEDITOXIN® may interact with medications that affect neuromuscular transmission, potentially enhancing their effects. Physicians should carefully review a customer’s medical history before administration to prevent complications. Notable interactions include:

• Aminoglycosides (e.g., gentamicin)
• Muscle relaxants
• Anticholinergic drugs

Recommendation: Physicians should review patient medication histories to avoid potentiated effects.

Clinical Studies and Real-World Outcomes

Extensive study data and customer feedback highlight MEDITOXIN®’s efficacy and safety across various medical and aesthetic applications.

Comparative Study Results

• Glabellar Lines: Clinical studies report that MEDITOXIN® delivers results comparable to OnabotulinumtoxinA, with no significant difference in adverse effects.
• Pediatric Cerebral Palsy: A study found that ≥60% of patients experienced improved spasticity within four weeks post-injection.
• Post-Stroke Upper Limb Spasticity: MEDITOXIN® demonstrated a similar efficacy and safety profile to Botox®.

Global Adoption and Patient Satisfaction

MEDITOXIN® is widely used worldwide due to its reliability, affordability, and positive customer feedback. As more patients report successful treatment outcomes, its reputation continues to grow in both medical and aesthetic fields.

MEDITOXIN® 200u Manufacturer and Regulatory Information

• Manufacturer: Medytox Inc.
• Shelf Life: 36 months from the manufacturing date.
• Compliance: Meets CE certification standards, ensuring adherence to safety and quality requirements.

For further details: Visit www.medytox.com.