Skin boosters are defined as biological materials or bio-actives that enhance or stimulate the skin’s functional capabilities. The aesthetic field uses these boosters to address structural changes associated with aging and other factors, such as corticosteroid-induced skin atrophy.
As skin boosters evolve, brands incorporate vital ingredients into their injectables, such as polynucleotides derived from salmon DNA and hyaluronic acid. Specifically, Rejuran and Profhilo skin boosters utilize these components to effectively address and rejuvenate each patient’s unique skin concerns.
This article will compare Rejuran vs Profhilo, their compositions, mechanisms of action, clinical efficacy, benefits, side effects, and the longevity of results.
Key Takeaways
- The Rejuran manufacturer utilizes polynucleotides derived from salmon DNA, while Profhilo injections capitalize on highly pure hyaluronic acid.
- These skin boosters can deliver various benefits, specifically anti-aging, due to Rejuran’s skin regeneration and Profhilo’s bio-remodeling effects.
- Medical practitioners must discuss the potential Profhilo and Rejuran side effects that may occur after the treatment.
- When administered by medical professionals, Rejuran and Profhilo can deliver long-lasting results and maximum benefits.
- The typical Rejuran treatment protocol requires three initial injections spaced three weeks apart, while Profhilo’s treatment protocol usually involves two to three injections, with a month between the first and second shots.
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Understanding Rejuran and Profhilo
Skin boosters continuously emerge as popular non-surgical solutions to address individuals’ skin concerns. When comparing Rejuran vs Profhilo, medical professionals first explain their unique compositions. They differ in their formulations’ key ingredients, allowing patients to decide which treatments suit their needs and concerns.
Rejuran’s manufacturer utilizes polynucleotides (PN) derived from salmon DNA. These PN facilitate skin regeneration, collagen synthesis, and tissue repair. Salmon DNA’s high compatibility with human skin significantly enhances Rejuran Healer’s efficacy in improving skin elasticity, texture, and hydration.
Meanwhile, Profhilo injections capitalize on highly pure hyaluronic acid (HA), which is made with their patented NAHYCO technology. This method results in a smooth HA gel injectable with extended stimulating activity on the dermal cells. Profhilo’s bio-remodeling properties lead to remodeling aging and sagging tissue.
Mechanism of Action
These skin boosters can combat aging with their specific mechanisms of action. Rejuran uses its polynucleotides derived from salmon DNA to stimulate collagen production, enhance skin elasticity, and promote tissue repair. By enhancing fibroblast activity, Rejuran effectively improves skin texture and diminishes the appearance of fine lines and wrinkles.
Furthermore, Profhilo addresses aging with its high hyaluronic acid (HA) concentration. This formulation deeply hydrates the skin and stimulates collagen and elastin production. Consequently, Profhilo’s bio-remodeling properties produce firmer, smoother, and more youthful skin.
Clinical Efficacy and Skin Concerns
A clinical study of Rejuran Healer conducted four treatments in two-week intervals. The findings revealed that the respondents received significant improvements in their full-face rejuvenation, including improved hydration, reduced wrinkles and sagging skin, and reduced pigmentation. Furthermore, more clinical studies highlight Rejuran Healer’s ability to revitalize, restore skin elasticity, hydrate, and normalize skin.
According to an open-label evaluation, the study’s conclusion showed that the improvements in facial parameters aligned with the bio-remodeling objectives and remained statistically significant. Both investigators and volunteers rated Profhilo’s tolerability and safety profile as good or excellent, highlighting the bio-remodeling claims of these stable hybrid cooperative complexes of its low- and high-molecular-weight hyaluronic acid.
While Rejuran lacks clinical evidence, medical professionals and individuals can look into Rejuran Healer reviews and patients’ before and after photos to see its benefits for the skin. Moreover, Profhilo has numerous reviews and testimonials showcasing its safety and efficacy in addressing facial skin concerns.
Benefits, Side Effects, and Longevity of Results
These skin boosters can deliver various benefits, specifically for anti-aging. The Rejuran salmon DNA component stimulates collagen production and tissue repair, improving skin elasticity, reducing aging signs, enhancing overall skin health, and delivering skin regeneration.
Meanwhile, due to Profhilo’s purest form of hyaluronic acid, this skin booster provides intense hydration. Similar to Rejuran, it can stimulate collagen production. Patients can achieve optimal results with visible lifting of the skin and improvement in overall skin texture and radiance.
Medical practitioners must discuss the potential Profhilo and Rejuran side effects that may occur after the treatment. These typical symptoms are temporary and may resolve within a few days to a week. By understanding these risks and using their expertise, they can ensure patient safety and allow them to manage these symptoms properly.
- Common Rejuran Side Effects: Injection site reactions, such as redness, swelling, and bruising.
- Common Profhilo Side Effects: Post-treatment discomfort, such as bumps, redness, swelling, pain, itching, bruising, or tenderness at the injection site.
Both skin boosters can deliver long-lasting results. However, Rejuran results can last up to 12 months, while Profhilo effects typically last within six months. Patients may receive maintenance treatments to sustain the impressive effects of these injectables.
Practical Considerations
Understanding the treatment procedure should help patients decide which skin booster to use between Rejuran vs Profhilo. Medical practitioners should discuss the treatment protocols of these injectables and equip patients with comprehensive information about them, allowing them to make informed decisions for their treatment.
The typical Rejuran treatment protocol requires three initial injections spaced three weeks apart. The Rejuran administration technique involves fine injections into the superficial dermis skin layer. The polynucleotides from salmon DNA are injected into targeted areas to stimulate cellular repair and collagen production.
Profhilo’s treatment protocol usually involves two to three injections, with a month between the first and second shots. Medical professionals can administer the third injection two months after the second. Profhilo requires injecting the hyaluronic acid into ten specific Bio-Aesthetic Points on the face. This method ensures even distribution and deep hydration, enhancing skin elasticity and firmness.
Despite the lack of data on patient satisfaction, Rejuran and Profhilo have earned high satisfaction with the impressive before and after improvements and photos of patient treatments. Rejuran’s polynucleotides contribute to skin regeneration, while Profhilo’s hyaluronic acid provides bio-remodeling effects.
Rejuran treatment sessions may range from $500 to $800, while Profhilo ranges between $600 to $900. Patients must seek the help of medical professionals for the exact cost comparison, as they would also consider their expertise, clinic, region, treatment area, and severity of concern. Furthermore, both treatments require maintenance sessions to sustain results.
Conclusion
When considering Rejuran vs Profhilo for anti-aging treatments, it is essential to understand these skin boosters’ unique compositions and mechanisms of action. Rejuran harnesses the power of polynucleotides derived from salmon DNA to promote skin regeneration and collagen synthesis, while Profhilo relies on highly pure hyaluronic acid to deliver intense hydration and stimulate collagen and elastin production.
Both treatments have demonstrated clinical efficacy in addressing aging-related skin concerns. Medical practitioners are crucial in discussing the potential benefits, side effects, and treatment protocols with patients to help them make informed decisions based on their unique needs. The choice between Rejuran and Profhilo will depend on individual skin concerns and treatment preferences.
FAQs
1. What are the key differences between Rejuran and Profhilo?
Rejuran utilizes polynucleotides derived from salmon DNA, while Profhilo injections capitalize on highly pure hyaluronic acid.
2. What are the benefits of Rejuran and Profhilo for anti-aging?
Rejuran stimulates collagen production and tissue repair, improving skin elasticity and delivering skin regeneration. Profhilo provides intense hydration, stimulates collagen production, and offers visible skin lifting.
3. How many treatments are typically required for Rejuran and Profhilo, and what is the spacing between treatments?
Rejuran’s typical treatment protocol requires three initial injections spaced three weeks apart, while Profhilo’s treatment protocol usually involves two to three injections, with a month between the first and second shots.
References
- Arora, G., Arora, S., Sadoughifar, R., & Batra, N. (2020). Biorevitalization of the skin with skin boosters: Concepts, variables, and limitations. Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.13871
- Sparavigna, A., & Tenconi, B. (2016). Efficacy and tolerance of an injectable medical device containing stable hybrid cooperative complexes of high- and low-molecular-weight hyaluronic acid: a monocentric 16 weeks open-label evaluation. Clinical, cosmetic and investigational dermatology, 9, 297–305. https://doi.org/10.2147/CCID.S114450
