NEXPLANON®

NEXPLANON® Product Description

NEXPLANON is a long-acting hormonal contraceptive used as birth control and to prevent pregnancy. Also, Nexplanon is a progestin hormone-containing rod containing 68 mg etonogestrel, preloaded in a sterile, single-use applicator for subdermal insertion.

• Provides contraception for up to three years.
• A single-rod progestin contraceptive that measures 4 cm in length and 2 mm in diameter.
• Designed for insertion under the skin of the inner side of the non-dominant upper arm.

How NEXPLANON Works and Its Benefits in Birth Control

NEXPLANON etonogestrel contraceptive prevents pregnancy and supports women’s reproductive health. This birth control implant offers years of low-maintenance contraception for each patient and is recommended by healthcare providers. Key benefits when doctors insert Nexplanon implant include:

• Highly effective: Pearl Index of 0.38 pregnancies per 100 women-years of use.
• Convenient: Does not require daily, weekly, or monthly administration.
• Rapid reversibility: Fertility can return as early as 7-14 days after removal.
• Radiopaque design implant allows easy localization using imaging methods.

NEXPLANON insertion by a health care provider ensures proper placement of this subdermal implant.

NEXPLANON® Ingredients

This contraceptive implant inserted in the subdermal into a patient contains:

• Etonogestrel levels (68 mg): A synthetic progestin suppressing ovulation.
• Barium sulfate (15 mg): Contains radiopaque etonogestrel for imaging.
• Magnesium stearate (0.1 mg): Stabilizer.

NEXPLANON® Indications and Treatment Applications as a Subdermal Implant

NEXPLANON is a hormone-releasing birth control implant indicated for use in women for the prevention of pregnancy and planned parenthood. Nexplanon works primarily by:

• Suppressing ovulation.
• Increasing cervical mucus viscosity, which inhibits sperm motility.
• Altering endometrial structure, reducing implantation likelihood.

NEXPLANON® Dosage and Administration

NEXPLANON is a subdermal implant inserted by a professional health care provider in the non-dominant upper arm. Administration of this birth control method involves:

• Insertion performed under aseptic conditions by trained healthcare professionals.
• Removal and replacement required by the end of three years.
• Specific timing considerations for insertion depending on the woman’s contraceptive history, postpartum status, or following abortion.

NEXPLANON® Side Effects and Warnings

While generally well-tolerated compared with oral contraceptives, NEXPLANON is a single-rod progestin contraceptive that may cause side effects that vary by individual. Here are information about some of them:

• Menstrual irregularities – May cause amenorrhea, frequent or prolonged bleeding.
• Common reactions – Headache (24.9%), acne (13.5%), breast pain (12.8%), and may cause weight gain in some people (13.7%).
• Sexual health changes – Some individuals report changes in libido or mood.
• Serious risks – Side effects that include thrombosis, ectopic pregnancy, and liver dysfunction.
• Insertion/removal complications – Pain, scarring, or implant migration.

NEXPLANON® Precautions and Contraindications

Information on the contraindications for NEXPLANON® include:

• Known or suspected pregnancy of a patient.
• History of thrombosis, liver disease, or progestin-sensitive cancers.
• Undiagnosed abnormal genital bleeding.

Precautions involve monitoring for:

• Remove Nexplanon implant if blood pressure becomes uncontrolled.
• Consider discontinuation if significant symptoms develop.
• Proper care and use in women with diabetes or hyperlipidemia.

Any patient receiving these services at a clinic should be monitored regularly. Consistent follow-ups every few months after Nexplanon insertion ensure the best care outcomes.

NEXPLANON® Long-Term Considerations

The implant is associated with reversible effects and requires monitoring over time:

• Potential impact on bone density is not fully established.
• Changes in weight and blood pressure should be monitored.

NEXPLANON® Manufacturer and Regulatory Information

For students and healthcare providers seeking detailed health information about the contraceptive, here is the NEXPLANON manufacturer and regulatory health information:

• Manufacturer: Organon USA LLC, a subsidiary of Organon & Co.
• Approval: Initial U.S. approval in 2001.
• Storage: Store this implant at controlled room temperature (25°C) with excursions permitted to 15-30°C.

NEXPLANON® FAQs

Here’s a list of questions frequently asked about NEXPLANON®.

How effective is NEXPLANON?

NEXPLANON has a failure rate of 0.38 pregnancies per 100 women-years, making it one of the most reliable contraceptive methods available.

Can the implant migrate after insertion?

Yes, there have been reports of migration, typically within the arm. Rare cases of migration to the pulmonary vasculature have been noted.

What should I do if the implant is not palpable?

Healthcare providers may use X-ray, ultrasound, or MRI to locate a non-palpable implant. Removal should be performed by a trained professional.

How soon does fertility return after removal?

Fertility can return as early as 7-14 days after removal, so alternate contraception should be initiated immediately if desired.

Are there risks during insertion or removal?

Complications may include pain, infection, or difficulty locating the implant, particularly if improperly inserted or migrated.