The global facial rejuvenation market has expanded significantly, growing from $15 billion in 2016 to a projected $25.11 billion within the next two years. This surge reflects a rising demand for treatments that help individuals restore a youthful appearance without undergoing invasive surgery.
Facial rejuvenation focuses on addressing volume loss, sagging skin, fine lines, wrinkles, and dullness. Minimally invasive options, such as hyaluronic acid-based dermal fillers, are often preferred over surgical alternatives. Among the top choices are Stylage and Juvederm, both known for delivering effective, long-lasting results.
In this article, we will compare Stylage vs Juvederm, exploring their formulations, clinical performance, longevity, and patient satisfaction to help you determine the best option for your aesthetic goals.
Key Takeaways
- Stylage employs IPN-like technology in its injectables, enhancing durability and elasticity.
- In contrast, Juvederm utilizes Vycross technology, which provides a smoother gel consistency.
- Both Stylage and Juvederm provide formulations with lidocaine, which helps to minimize patient discomfort during injections.
- Stylage fillers can provide six to eighteen months, whereas Juvederm typically offers results lasting nine to twelve months.
- Although both fillers are generally well-tolerated, patients should know that common side effects from Juvederm and Stylage may occur after treatment.
About: Medica Depot is your trusted all-in-one supplier, offering a range of high-quality medical injectables and supplies. Order Stylage online at Medica Depot today! Whether for health professionals, plastic surgeons, dermatologists, licensed estheticians, or other specialists, we can offer genuine, brand-name products you may need. With Medica Depot, we prioritize serving you better to improve the patient’s quality of life.
Understanding Stylage and Juvederm Fillers

Laboratoires Vivacy and Allergan Aesthetics have developed leading dermal fillers, Stylage and Juvederm, to address a wide range of facial skin concerns.
Stylage uses advanced IPN-like technology to enhance the elasticity and durability of its fillers, delivering natural-looking, long-lasting results. Its comprehensive product line includes:
- Stylage S, M, L: Ideal for fine to deep wrinkles.
- Stylage XL and XXL: Designed for restoring volume.
- Stylage Lips Lidocaine and Lips Plus: Specially formulated for lip enhancement.
Juvederm employs Vycross Technology, creating smooth, gel-like fillers that seamlessly blend with the skin. This range includes:
- Voluma XC and Volux XC: For contouring and volume restoration.
- Vollure XC: Targeting moderate wrinkles.
- Ultra XC and Ultra Plus XC: For versatile facial treatments.
- Volbella XC: Designed for subtle lip enhancement.
Both brands are trusted by medical professionals for their proven efficacy and adaptability to diverse patient needs. Stylage vs Juvederm is often a choice influenced by the specific goals of the treatment and the unique preferences of the patient.
Formulation and Composition
Stylage combines hyaluronic acid (HA) with antioxidants like mannitol or sorbitol. These antioxidants reduce inflammation and enhance filler longevity, with effects lasting 6 to 12 months depending on the product. This unique blend supports skin rejuvenation while addressing volume loss.
On the other hand, Juvederm employs Vycross Technology, which integrates low and high-molecular-weight HA into a smooth gel. This technology enhances filler durability, offering natural-looking results lasting up to a year or longer, depending on the treatment area and specific product used.
The inclusion of lidocaine has been a known process in many dermal fillers, highlighting the industry’s commitment to enhancing patient experience. Fortunately, both Stylage and Juvederm offer formulations that include lidocaine to minimize patient discomfort during injections.
Comparison of Hyaluronic Acid Concentration and Viscosity
Stylage generally features a higher HA concentration, ranging from 16 mg/g to 26 mg/g, which enhances its volumizing effects. Juvederm fillers, with HA concentrations between 15 mg/g and 24 mg/g, achieve a cohesive, smooth texture suitable for structural support.
Stylage’s precise formulations excel in creating natural-looking enhancements, making it a go-to for subtle rejuvenation. Conversely, Juvederm’s smoother gel consistency ensures durability and is ideal for areas requiring more structural integrity.
Both brands incorporate lidocaine in many of their products, ensuring a more comfortable injection experience for patients. This shared feature highlights their commitment to patient comfort during minimally invasive procedures.
Clinical Studies and Efficacy
The 18-month Beauty Volume study validated the effectiveness and safety of Stylage XL Lidocaine for facial volume augmentation and restoration. Patients reported high satisfaction with the aesthetic improvements, with results persisting at 12 and 18 months. Additionally, Stylage XL Lidocaine demonstrated a favorable safety profile and was well tolerated by the study participants.
After over nine months, 75% of nasolabial folds treated with Juvederm Ultra and 81% treated with Juvederm Ultra Plus maintained clinically significant correction. This randomized controlled trial confirmed that Juvederm injectable gel provides reliable, long-term results. Juvederm Ultra generally lasts over nine months, while Juvederm Ultra Plus can sustain results for a year or longer.
When comparing Stylage vs Juvederm, individuals may consider the longevity of the results of these minimally invasive treatments. Due to the addition of antioxidants, Stylage fillers can offer more prolonged effects than Juvederm.
- Stylage’s Longevity: Filler results can last six to eighteen months, depending on the product used and the targeted treatment area.
- Juvederm’s Longevity: These HA-based fillers typically last between nine to twelve months but can last longer based on the filler.
Patient Satisfaction and Outcomes
While there are limited reports on Stylage’s patient satisfaction, visual evidence in before-and-after photos showcases the safety and efficacy of treatments like Stylage lip fillers in delivering optimal treatment outcomes. These patients have received enhancements for their lips, providing a more defined and symmetrical pout.

Meanwhile, Juvederm received a high 90% satisfaction rate in RealSelf. This figure underscores the positive patient outcomes associated with these minimally injection treatments. This patient has shared their impressive experience with Juvederm injections for their nose, chin, jaw, and midface regions.

Advantages and Drawbacks
Stylage and Juvederm each offer distinct benefits tailored to different patient needs, making them leading choices in the dermal filler market.
Stylage fillers stand out for their innovative features:
- Antioxidants: The inclusion of mannitol or sorbitol minimizes post-injection inflammation and extends the filler’s longevity.
- IPN-like Technology: This proprietary feature enhances filler elasticity and durability, ensuring long-lasting, natural-looking results.
Meanwhile, Juvederm is renowned for its FDA-approved collection of fillers, ensuring safety and efficacy. Its unique benefits include:
- Smooth Gel Consistency: Offers even distribution for flawless application.
- Vycross Technology: Combines low and high-molecular-weight hyaluronic acid, extending filler longevity and improving integration into the skin.
Potential Drawbacks of Each Filler
While generally safe and effective, both Stylage and Juvederm can have temporary side effects. Understanding these potential drawbacks can help patients set realistic expectations.
- Stylage Side Effects: Common reactions include redness, swelling, bruising, itching, or pain at the injection site. These usually resolve within a few days.
- Juvederm Side Effects: Patients may experience redness, swelling, tenderness, lumps, bruising, or discoloration. These effects are typically mild and temporary.
Conclusion
Stylage and Juvederm provide effective non-surgical solutions for facial rejuvenation, each with distinct strengths. Stylage excels in volume enhancement and longevity with its antioxidant-rich formula, while Juvederm’s Vycross technology offers smooth application and versatility for various facial areas.
Choosing the right filler depends on individual needs and consultation with a professional, ensuring natural, long-lasting results for a youthful appearance.
FAQs
1. What are the main differences between Stylage and Juvederm fillers?
Stylage uses IPN-like technology, enhancing durability and elasticity, while Juvederm employs Vycross technology for a smoother gel consistency. Stylage fillers generally have a higher concentration of hyaluronic acid, leading to longer-lasting effects.
2. How long do the results from Stylage and Juvederm fillers typically last?
Stylage fillers can last six to eighteen months, depending on the product, whereas Juvederm often provides results lasting nine to twelve months.
3. Do Stylage and Juvederm fillers contain lidocaine?
Both Stylage and Juvederm formulations include lidocaine to help minimize discomfort during injections, enhancing the overall patient experience.
References
- Statista. (2024, February 22). Facial rejuvenation market size worldwide from 2016-2026. https://www.statista.com/statistics/988827/facial-rejuvenation-revenue-global-market/
- Mojallal, A. (2023). Efficacy and Safety of Stylage XL Lidocaine for the Restoration and/or Augmentation of Facial Volume: The Beauty Volume Study. Aesthetic Surgery Journal Open Forum, 5. https://doi.org/10.1093/asjof/ojad056