In 2018, the demand for non-surgical hyaluronic acid procedures experienced a remarkable 54% increase. Notably, an impressive $544 million was allocated to these aesthetic treatments. Among these procedures, injectable dermal fillers emerged as the second most favored non-invasive option.
Recent advancements in aesthetic medicine have positioned hyaluronic acid (HA) dermal fillers as a prominent solution for beauty enhancements. Individuals seeking to address skin or facial concerns—such as facial wrinkles or fine lines—can benefit from the tailored HA injectables provided by both Revanesse and Juvederm. These treatments cater to each patient’s unique needs, ensuring optimal outcomes.
This article will compare Revanesse vs Juvederm, their compositions, mechanisms of action, clinical efficacy, safety profiles, and practical considerations.
Key Takeaways
- Due to its similar active ingredient, Revanesse and Juvederm boost hydration levels, add volume, and maintain skin firmness and smoothness when injected.
- Both injectables have US FDA approval, and while they’re generally safe to use, patients should expect potential side effects to occur after their treatments.
- With the guidance and expertise of medical professionals, patients can receive optimal outcomes and safe procedures with Juvederm and Revanesse products.
- The duration of results of Juvederm and Revanesse products are 12 to 24 months and around 12 months, respectively.
- To avoid further complications during and after the procedure, it’s essential to follow the US FDA-approved indications and treatment protocols for these injectables.
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Composition and Mechanism of Action

When comparing hyaluronic acid (HA) dermal fillers like Revanesse vs Juvederm, medical professionals must understand their unique composition and mechanism of action. They can then determine which brand suits each patient’s health condition and skin concern to ensure a safe and effective aesthetic treatment.
Revanesse offers two US Food and Drug Administration (FDA)-approved HA dermal fillers for facial aging and lip concerns. Its solution is an injectable hydrogel containing bioresorbable cross-linked HA 25 mg/mL and 0.3% lidocaine to ensure patient comfort during the procedure.
Juvederm developed six HA dermal fillers, each with specific indications for aesthetic enhancements in various facial regions and concerns. It capitalizes on HA as its active ingredient, combined with lidocaine, and utilizes Vycross Technology to cross-link and ensure smooth gel consistency.
Due to its similar active ingredient, Revanesse and Juvederm boost hydration levels, add volume, and maintain skin firmness and smoothness when injected. Their HA solution retains moisture and helps in immediate volumization to enhance facial features.
Clinical Efficacy and Safety Profiles

Both Revanesse and Juvederm received the approval of the US Food and Drug Administration for their hyaluronic acid dermal fillers, ensuring their safety and efficacy in addressing aesthetic issues. According to a study on fillers, Juvederm is the most commonly used HA dermal filler, while Revanesse is the most recently FDA-approved HA filler.
Revanesse fillers have undergone rigorous clinical trials, and a controlled study highlights the high treatment success rates associated with Revanesse Lips+. Moreover, this injectable treatment received high satisfaction with their Revanesse Lips+ outcomes.
Meanwhile, a randomized controlled trial revealed that Juvederm Ultra or Ultra Plus significantly improved the correction of subjects’ nasolabial folds. These Juvederm fillers also provided long-lasting improvements compared to a dermal filler, lasting more than nine months after treatment.
Both injectables have US FDA approval, and while they’re generally safe to use, patients should expect potential side effects to occur after their treatments. These common Juvederm and Revanesse side effects typically last a few days to a week; however, if they persist, patients must seek immediate medical attention.
- Revanesse Side Effects: Bleeding, bruising, swelling, and pain.
- Juvederm Side Effects: Redness, swelling, pain, and tenderness.
Furthermore, the lidocaine component in Revanesse and Juvederm helps minimize patient discomfort during the procedure. To avoid further complications during and after the procedure, following the approved indications and treatment protocols for these injectables from the US FDA is essential.
Practical Considerations

With the guidance and expertise of medical professionals, patients can receive optimal outcomes and safe procedures with Juvederm and Revanesse products. Hyaluronic acid procedures like these injections offer quick treatment and minimal downtime, making it a viable option for aesthetic concerns.
- Treatment Areas for Revanesse: Facial wrinkles and folds and lip augmentation.
- Treatment Areas for Juvederm: Jawline, chin, facial wrinkles and folds, lips, and undereye hollows.
The recommended Revanesse age for prospective patients interested in the treatment is at least 22, while Juvederm requires at least 21. This ensures that adult individuals undergo the injection treatment; however, patients must meet their trusted medical professionals for a thorough consultation to determine patient suitability and create a tailored treatment plan to maximize the treatment’s benefits and achieve their desired results.
Moreover, both injection brands received high satisfaction ratings from user reviews on RealSelf. Revanesse dermal filler reviews reached an average of 71%, while Juvederm received a 91% satisfaction rate. The cost for Juvederm and Revanesse products may depend on the location of the clinic or provider, the treatment area, and the product used for the procedure.
The typical range of Revanesse products at Medica Depot ranges from $195 to $271, while Juvederm injections run from $179 to $359. It’s worth noting that patients must seek providers’ guidance for a more precise cost comparison. In addition, they may also compare the duration of results to determine which brand they should receive for their aesthetic enhancement.
- Duration of Results for Revanesse: Aesthetic enhancements can last up to 12 months
- Duration of Results for Juvederm: With optimal treatment, results may last from 12 to 24 months, depending on the formula used and the area treated.
Conclusion
Juvederm and Revanesse products effectively address facial aging and lip concerns. They harness the power of hyaluronic acid to boost hydration levels and maintain skin firmness. While Revanesse and Juvederm have undergone rigorous clinical trials and received US FDA approval, patients must know potential side effects, proper treatment areas, benefits, and treatment processes before their procedure.
Medical professionals are crucial in guiding patients toward optimal outcomes and safe procedures with Revanesse and Juvederm fillers. With the convenience of quick treatment and minimal downtime, hyaluronic acid procedures with Revanesse and Juvederm offer viable options for individuals seeking non-invasive aesthetic enhancements.
FAQs
1. What are the key differences between Revanesse and Juvederm dermal fillers?
Revanesse and Juvederm are hyaluronic acid dermal fillers with similar mechanisms of action, but they differ in their specific compositions, treatment duration, and approved treatment areas.
2. Are there notable side effects associated with Revanesse and Juvederm injections?
Common side effects of Revanesse and Juvederm injections include swelling, pain, and tenderness. These typically subside within a few days to a week. However, patients should seek immediate medical attention if these side effects persist.
3. What are the recommended treatment areas for Revanesse and Juvederm injections?
Revanesse is recommended for treating facial wrinkles and folds and for lip augmentation. At the same time, Juvederm is suitable for the jawline, chin, facial wrinkles and folds, lips, and undereye hollows.
References
- The Aesthetic Society. (n.d.). The Aesthetic Society releases annual statistics revealing significant increases in face, breast, and body in 2021. https://www.theaestheticsociety.org/media/press-releases/aesthetic-society-releases-annual-statistics-revealing-significant-increases
- Pinsky, M. A., Thomas, J. A., Murphy, D. K., Walker, P. S., & Juvéderm vs. Zyplast Nasolabial Fold Study Group (2008). Juvéderm injectable gel: a multicenter, double-blind, randomized study of safety and effectiveness. Aesthetic surgery journal, 28(1), 17–23. https://doi.org/10.1016/j.asj.2007.09.005