Did you know that the global aesthetic injectables market is projected to grow by 12 to 14 percent annually over the next five years? This upward trend in the aesthetic field underscores the growing number of individuals seeking various injectable brands for facial and body rejuvenation.
As the market for aesthetic injectables grows, numerous brands compete for rejuvenation. Aesthetic professionals play a crucial role in guiding individuals toward the most suitable filler for their skin concerns. While comparing Radiesse and Restylane, they consider these injectables’ distinct ingredients and mechanisms, ensuring safe and effective aesthetic outcomes.
This article will thoroughly compare Radiesse vs Restylane, their compositions, mechanisms of action, clinical efficacy, and safety profiles.
Key Takeaways
- Radiesse vs Restylane injectables offer different active ingredients but can deliver optimal outcomes with the help of licensed and experienced aesthetic providers.
- Radiesse and Restylane are US FDA-approved dermal fillers that address facial aging signs and volume loss.
- While both injections are generally safe for most individuals, follow-up appointments with their medical professionals can help them monitor the progress and any other Restylane or Radiesse side effects.
- Medical professionals can determine the most suitable Radiesse or Restylane injections for each individual’s facial or body concerns.
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Introduction to Radiesse and Restylane
Dermal fillers are injectable substances that moisturize the skin, plump up wrinkles, fill in folds, smoothen lines, and restore volume in the face. This minimally invasive procedure enhances facial features and helps individuals appear more youthful. These injectables offer various benefits that can deliver satisfactory results to patients.
- Natural-Looking Outcomes
- Quick Procedure
- Minimal Downtime
- Temporarily Addresses Facial Aging Signs
- Longer-Lasting Results
- Immediate Results After Treatment
Among many dermal filler brands, medical professionals may compare Radiesse vs Restylane for their unique mechanisms and effective solutions for aging skin concerns. These injectables offer different active ingredients but can deliver optimal outcomes with the help of licensed and experienced aesthetic providers.
Selecting the appropriate filler or facial rejuvenation is crucial for natural-looking results and patient satisfaction and safety. Seeking a medical professional can significantly impact the treatment procedure as they know what factors to consider based on the patient’s medical history, previous treatments, desired goals, and aesthetic concerns. Choosing the suitable filler includes factors such as:
- Mechanism of Action
- Outcome Longevity
- Ease of Injection
- Specific Aesthetic Goals
- Approved Uses and Indications
Composition and Mechanism of Action
Despite their safety and efficacy, Radiesse and Restylane offer different injectable ingredients and mechanisms. It’s worth noting that Radiesse has two injectables (Radiesse and Radiesse+), while Restylane has a collection of dermal fillers with specific indications for facial rejuvenation.
Radiesse consists of calcium hydroxyapatite (CaHA) gel microspheres suspended in a gel carrier. It contains approximately 30% CaHA and 70% gel carrier by volume. When injected, this CaHA injectable provides immediate visible improvements and, over time, stimulates collagen production, leading to an extended correction and increased satisfaction. Radiesse builds structural scaffolding by stimulating collagen for a year or longer.
On the other hand, Restylane capitalizes on hyaluronic acid (HA) as its active ingredient, along with two unique technologies: NASHA and XpresHAn Technology. Once injected, Restylane delivers immediate skin improvement by integrating with dermal tissue, binding with water molecules, and maintaining volume. Restylane treatment effects generally last six months or more, gradually disappearing from the body.
Considering their differences, medical professionals can help patients decide between Radiesse vs Restylane. These providers’ expertise and knowledge can explain and discuss which injectable filler fits patients’ concerns, as both can deliver effective results.
Clinical Efficacy
A study by Green et al. (2024) emphasized that the Radiesse (+) treatment resulted in significant and enduring enhancements in jawline contour, which was well-tolerated by patients over 60 weeks. Moreover, adverse events primarily involved procedure-related or Radiesse (+) events were predominantly mild and resolved.
Furthermore, diluted and hyper-diluted Radiesse offers versatile treatment options, delivering the desired dermal rejuvenation without the intense volumizing effects of the undiluted product. As a result, there has been a surge in off-label use, including treating skin laxity in the face, neck, decolletage, arms, abdomen, buttocks, and thighs.
A clinical trial on Restylane revealed that comprehensive facial treatments yielded sustained aesthetic enhancements, as both study participants and investigators observed. High subject satisfaction persisted for 24 months following a single re-treatment. Additionally, repeated treatment for various facial indications demonstrated a favorable safety profile.
Moreover, a randomized clinical trial compared Restylane with bovine collagen for nasolabial fold treatment. This study demonstrated that the stabilized hyaluronic acid of non-animal origin (Restylane) offers a more enduring aesthetic enhancement than bovine-derived collagen and exhibits commendable tolerability.
Radiesse and Restylane are US FDA-approved dermal fillers that address facial aging signs and volume loss. They offer minimally invasive, in-office treatments that yield immediate results. While specific studies comparing Radiesse and Restylane’s efficacy are unavailable, both fillers have advantages.
Radiesse can offer longer-lasting results due to its unique collagen stimulation once the body absorbs the gel. It also has better efficacy in addressing moderate to severe facial wrinkles and lines, but Restylane has more indications for full-face rejuvenation, thanks to its collection of fillers.
Safety Profiles
In addition to the dermal fillers’ benefits, medical professionals should discuss the potential risks that these injectables can cause. Equipping patients with comprehensive treatment information can help them make informed healthcare decisions. Restylane and Radiesse side effects are often temporary and may resolve independently.
- Common Radiesse Side Effects: Bruising, redness, swelling, pain, and itching at the injection site.
- Common Restylane Side Effects: Swelling, redness, pain, bruising, headache, tenderness, lump formation, itching at the injection site, and impaired hand function.
Radiesse and Restylane have favorable safety profiles, but it’s worth understanding that rare complications may occur. Understanding how to recognize symptoms of adverse events and unexpected side effects allows patients to seek immediate medical attention for proper management.
While both injections are generally safe for most individuals, follow-up appointments with their medical professionals can help them monitor the progress and any other Restylane or Radiesse side effects. Individual responses can vary, so consultation with a qualified provider is essential to ensure a safe and effective treatment.
Practical Considerations
Aside from their difference in active ingredients and mechanisms, Radiesse and Restylane also differ in their treatment areas. Additionally, medical professionals may recommend these injectables due to their US Food and Drug Administration approval for facial wrinkles, skin folds, and volume loss.
- Treatment Areas Suitable for Radiesse: This injectable can help smooth moderate to severe facial wrinkles and folds, correcting volume loss in the back of the hands. Radiesse (+) can help in jawline contouring.
- Treatment Areas Suitable for Restylane: Each Restylane product has specific treatment areas. These injectables have indications for correcting moderate to severe facial wrinkles and folds, volume loss, perioral wrinkles, lip augmentation, chin augmentation, cheek augmentation, and the under-eye area.
Medical professionals can determine the most suitable Radiesse or Restylane injections for each individual’s facial or body concerns. While these treatment outcomes are temporary, their mechanism of action and formulation can still offer long-lasting results.
- Radiesse: Natural-looking results of Radiesse can last a year or more in many patients.
- Restylane: Depending on the product used and treatment area, Restylane treatment outcomes can last six to 18 months.
Based on an online user rating and review platform, RealSelf, Restylane treatments have received a higher average rating of 89% than Radiesse’s 67% patient reviews. In addition to these ratings, both can work effectively for aging skin; however, outcomes depend on specific concerns, the filler used, and the skills and expertise of the medical professional.
Conclusion
The comprehensive comparison of Radiesse and Restylane highlights the diverse options available for individuals seeking facial and body rejuvenation through aesthetic injectables. These injectables’ distinct compositions and mechanisms of action offer unique benefits, such as long-lasting results and immediate improvements.
Radiesse and Restylane have demonstrated clinical efficacy and safety in various studies, emphasizing their potential to deliver enduring aesthetic enhancements with high patient satisfaction. Understanding these differences and clinical evidence can assist medical professionals and individuals in making informed decisions to achieve the desired aesthetic outcomes through minimally invasive procedures.
FAQs
1. What are the key differences between Radiesse and Restylane?
The main difference lies in their compositions and mechanisms of action. Radiesse contains calcium hydroxyapatite gel microspheres, stimulating collagen production for long-lasting results, while Restylane capitalizes on hyaluronic acid and integrates with dermal tissue for immediate skin improvement.
2. How can medical professionals help in choosing between Radiesse and Restylane?
Medical professionals are crucial in guiding patients toward the most suitable filler by considering factors such as mechanism of action, outcome longevity, ease of injection, specific aesthetic goals, and approved uses and indications.
3. What clinical evidence supports the efficacy and safety of Radiesse and Restylane?
Clinical studies have shown that Radiesse and Restylane offer enduring aesthetic enhancements with high patient satisfaction. The studies demonstrate significant and long-lasting improvements in facial areas and favorable safety profiles for both injectables.
References
- Leclerc, O., Peters, N., Scaglione, A., & Waring, J. (n.d.). From extreme to mainstream: The future of aesthetics injectables | McKinsey. Www.mckinsey.com. Retrieved July 8, 2024, from https://www.mckinsey.com/industries/life-sciences/our-insights/from-extreme-to-mainstream-the-future-of-aesthetics-injectables
- Green, J. B., Del Campo, R., Durkin, A. J., Funt, D. K., Nasrallah, N., Martinez, K., & Moradi, A. (2024). Long‐term duration and safety of Radiesse (+) for the treatment of jawline. Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.16436
