A study by Sylwia and Krzysztof (2017) demonstrated the effectiveness of intradermal mesotherapy in reducing cellulite. This safe and minimally invasive treatment significantly decreased the surface area of the serrated hypodermis-dermis junction and reduced hypodermis thickness compared to baseline measurements, highlighting its potential for skin improvement.
Cellulite is a common yet distressing condition that predominantly affects women, causing uneven skin texture and dimpling. While various therapeutic approaches aim to improve its appearance or severity, many individuals seek effective solutions that deliver noticeable results and enhance skin quality. Understanding the composition of treatments like Alidya provides valuable insights into their effectiveness in managing cellulite.
In this article, we will examine Alidya’s ingredients, their roles in cellulite treatment, safety and efficacy, and potential risks associated with the procedure.
Key Takeaways
- Alidya is an injectable treatment for cellulite formulated with active ingredients like polyamino acid gel, which promotes tissue regeneration and enhances skin elasticity.
- The combination of Alidya’s ingredients works synergistically to improve microcirculation and support collagen production, effectively reducing the appearance of cellulite.
- Although Alidya has received CE approval, it lacks comprehensive clinical trials for FDA approval, leading to some reservations about its safety and efficacy in the U.S. market.
- Common side effects, such as redness and swelling, may occur with Alidya, and patients should be assessed for contraindications to ensure a safe treatment experience.
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What are the Active Ingredients in Alidya?

Marllor Biomedical has meticulously formulated Alidya, an injectable solution designed to prevent and treat cellulite. By combining potent ingredients, Alidya targets the underlying causes of cellulite formation while ensuring safety and efficacy. The key components include:
- Polyamino Acid Gel: Enhances tissue regeneration and hydration by supplying essential amino acids.
- 1-4 Glycosidic: Maintains formulation stability, ensuring effectiveness.
- Amino Acid Buffer System with Sodium Bicarbonate Corrector: Balances pH levels to enhance performance and reduce irritation.
- D-(+) Alpha-D-glucopyranose: Provides energy for cellular processes, supporting skin health.
- Osmolarity Regulator: Maintains osmotic balance, preventing tissue damage.
- Sodium Ethylenediaminetetraacetic Acid (EDTA): Binds metal ions, improving stability and effectiveness.
Polyamino acid gel is particularly vital in Alidya, as it supplies amino acids essential for synthesizing collagen and elastin—key components for skin elasticity, firmness, and texture. This biocompatible matrix supports skin repair and tissue regeneration, playing a central role in the treatment’s effectiveness.
In cellulite treatment, the polyamino acid gel works synergistically with other active ingredients to promote skin regeneration, improve hydration, and support metabolic activity. It also facilitates even distribution and absorption of key components like Sodium EDTA and mannitol within the targeted tissues, ensuring optimal results.
How Do Alidya Ingredients Work to Improve Cellulite?

Alidya’s polyamino acid gel strengthens the extracellular matrix by providing essential amino acids. This process supports collagen and elastin synthesis, which are critical for skin firmness, elasticity, and improved texture. When combined with other active ingredients, Alidya delivers potent results in reducing the appearance of cellulite.
Additionally, Alidya’s components promote lipolysis, reducing the size and number of fat cells. This minimizes fat protrusion into the dermis, smoothing the skin and decreasing the visibility of cellulite. By addressing the damage caused by localized fat deposits and poor microcirculation, Alidya takes a comprehensive approach to repair, resulting in smoother, more uniform skin.
The Safety and Efficacy of Alidya Ingredients

The lack of clinical trials and studies on Alidya has prevented it from obtaining approval from the US Food and Drug Administration (FDA). The FDA requires extensive testing to confirm a product’s safety and efficacy before granting market authorization.
Despite this, Alidya has earned CE approval in the European Union, allowing its broader use in countries like the United Kingdom. Developed by Marllor Biomedical, Alidya highlights a research-driven focus on treating cellulite with its carefully formulated ingredients, designed to ensure safety and deliver optimal treatment outcomes.
The combined action of Alidya’s ingredients addresses the root causes of cellulite. These components work together to enhance microcirculation, boost collagen production, and support tissue regeneration. This synergy effectively reduces cellulite and improves the overall appearance of the skin.
Potential Side Effects and Contraindications
While Alidya is generally well-tolerated, some potential side effects may occur. Alidya cellulite reviews often highlight positive patient experiences and results, but typical injection site-related reactions may include:
- Redness
- Swelling
- Bruising
- Discomfort
Rare side effects, such as infection, allergic reactions, or skin discoloration, may occur due to unsterilized conditions, improper treatment protocols, or contraindications. Contraindications include:
- Active infections
- Hypersensitivity to any Alidya ingredients
- Certain medical conditions
- Pregnancy and breastfeeding
Proper patient assessment and tailored treatment plans are essential to ensure the safety and suitability of Alidya treatments. Practitioners should provide patients with comprehensive information about the procedure, empowering them to make informed decisions. Adhering to aftercare instructions is also critical for a safe recovery and maximizing the benefits of Alidya.
Conclusion
Alidya provides an innovative approach to cellulite treatment through its carefully selected ingredients, which target the underlying causes of this common skin condition. The combination of polyamino acid gel and other active components not only aids in tissue regeneration but also enhances skin firmness and appearance.
As with any injectable treatment, patient safety should be a priority. Individuals considering Alidya must undergo a thorough assessment to identify potential contraindications and ensure the treatment aligns with their health needs. By doing so, patients can make informed decisions and maximize their chances for successful outcomes in their cellulite treatment journey.
FAQs
1. What are the main ingredients in Alidya, and how do they work?
Alidya primarily contains a polyamino acid gel, 1-4 glycosidic, and amino acid buffer systems, among other ingredients. These ingredients work together to promote skin hydration, improve elasticity, and support collagen production, ultimately reducing the appearance of cellulite.
2. Is Alidya FDA approved?
No, Alidya has not undergone the rigorous clinical trials needed for FDA approval in the U.S. However, it has received CE approval, indicating safety and efficacy in the European market.
3. What side effects can occur with Alidya treatment?
Common side effects include redness, swelling, and bruising at the injection site. More serious effects, like infections or allergic reactions, may occur more rarely, especially in individuals with specific contraindications.
References
- Sylwia, M., & Krzysztof, M. R. (2017). Efficacy of intradermal mesotherapy in cellulite reduction – Conventional and high-frequency ultrasound monitoring results. Journal of Cosmetic and Laser Therapy, 19(6), 320–324. https://doi.org/10.1080/14764172.2017.1334927
- ALIDYA (Anti LipoDystrophic Agents). (n.d.). In Marllor Biomedical. Marllor Biomedical. Retrieved January 23, 2025, from https://www.marllor.com/_files/ugd/d005d2_e472d88dcc0042f7be6e590d879ee34e.pdf