Semaglutide 50mg

What is Semaglutide (50 mg)?

Semaglutide (50 mg) is a synthetic peptide analog used in laboratory research to investigate metabolic regulation and related signaling activity in experimental systems. It is commonly used to explore how peptide-based compounds influence nutrient-response pathways, cellular communication, and downstream biological readouts in preclinical or in vitro models. With a defined sequence and high purity, it supports controlled study designs where material consistency and reproducibility are crucial.

Product Specifications

• CAS Number: 910463-68-2
• Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH
• Category: Peptides
• Subcategory: Weight Loss & Metabolic Peptides
• Chemical Formula: C₁₈₇H₂₉₁N₄₅O₅₉
• Molecular Weight:4113.6 g/mol
• Synonyms: NN9535
• Purity: ≥99% (99.88% typical)
• Packaging Format: 50 mg
• Storage Conditions: Store at -20°C, avoid light exposure
• Designation: For Laboratory Research Use Only

Key Characteristics of Semaglutide (50 mg)

• High Purity: ≥99% purity, designed for research environments where consistency is essential.
• Defined Peptide Sequence: Supports repeatable experimental setup and comparison across studies.
• Commonly Studied: Frequently used in metabolic research to evaluate peptide-driven signaling and regulation.
• Larger Packaging Format: Supplied in a 50 mg format for laboratories requiring a larger mass for project work or method development.
• Light- and Temperature-Sensitive: Store at -20°C and protect from light.
• Research Use Only: Not intended for diagnostic, therapeutic, or consumer applications.

How Semaglutide (50 mg) Supports Research

In research settings, Semaglutide is used to investigate metabolic regulation and peptide-related signaling. It is often included in studies examining how metabolic pathways respond to peptide-based compounds in controlled experimental systems. Researchers commonly use it to support projects focusing on energy balance biology, nutrient signaling, and metabolic model development, where a consistent, well-characterized peptide reagent is needed.

Research Applications & Usage Information

Semaglutide (50 mg) is commonly used as a research reagent in studies such as:

• Metabolic Signaling Studies: Exploring pathway activity and downstream cellular responses in experimental models.
• Glucose and Energy Regulation Research: Investigating how metabolic control systems respond to peptide-based tools.
• Appetite and Nutrient-Response Pathway Research: Focused on characterizing signaling networks in preclinical or in vitro models, rather than clinical outcomes.
• Receptor Interaction and Binding Characterization: Used in screening assays, comparative profiling, or method validation.
• Model Development and Benchmarking: Evaluating readouts, assay performance, or reproducibility using a standardized peptide reference material.
• Stability and Analytical Testing: Including identity confirmation, purity checks, and comparability testing in lab workflows.

Note: Research applications vary depending on laboratory protocol and model selection. This material is intended for laboratory research only.

Handling and Storage Recommendations

• Store at -20°C.
• Protect from light exposure by keeping the vial in its original packaging or a light-limiting container when not in use.
• Avoid repeated warming and freezing.
• Keep the container tightly closed and handle with standard laboratory precautions to reduce the risk of contamination.
• Label clearly for research use and store according to your lab’s chemical hygiene and inventory procedures.

Research Use Only Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

1. Lau J, Bloch P, Schäffer L, et al. Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. J Med Chem. 2015;58(18):7370-7380. doi:10.1021/acs.jmedchem.5b00726
2. Loomba R, Abdelmalek MF, Armstrong MJ, et al. Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial. Lancet Gastroenterol Hepatol. 2023;8(6):511-522. doi:10.1016/S2468-1253(23)00068-7
3. Knudsen LB, Lau J. The Discovery and Development of Liraglutide and Semaglutide. Front Endocrinol (Lausanne). 2019;10:155. Published 2019 Apr 12. doi:10.3389/fendo.2019.00155

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