Mazdutide (10mg)
All products are 100% genuine and sourced from trusted manufacturers, with authenticity that can be verified for complete peace of mind.
Order exactly what you need with no minimum quantity required, whether it’s a single unit or a larger order.
Your order is guaranteed to arrive safely, with full shipment tracking and dedicated support to ensure a smooth delivery experience.
Your payments are protected with industry-standard encryption and trusted payment providers, ensuring every transaction is safe, private, and secure.
99% PURITY GUARANTEE
Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC). Full analytical reports are available in the Certificate of Analysis section.
The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.
This product is intended for research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and should only be handled by qualified professionals.
Strength: 10 mg
CAS: 2259884-03-0
Chemical Formula: C₂₁₀H₃₂₂N₄₆O₆₇
Molecular weight: 4563.06 g/mol
Peptide Sequence: His-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Glu-Lys-Lys-Ala-Lys-{AEEA-AEEA-γGlu-Nonadecanoic acid}-Glu-Phe-Val-Glu-Trp-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-NH2
Synonyms: IBI-362 (or IBI362) LY-3305677 (or LY3305677)
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
Mazdutide (10 mg) is a synthetic, long-acting investigational peptide (also known as IBI-362 / LY-3305677) designed as a dual GLP-1 receptor and glucagon receptor (GLP-1R/GCGR) agonist for laboratory research into metabolic hormone signaling. Research suggests that it may help scientists explore how the body regulates appetite, blood sugar, and energy use by acting on two key hormone pathways involved in metabolism.
-
Cold chain shipping available for temperature-sensitive products.
-
Orders are processed within 1–2 business days.
-
Delivery timelines vary by destination and shipping method — view our Shipping Policy for region-specific estimates.
-
Tracking information will be provided once shipped.
-
No order minimum applies.
-
If your shipment is delayed, lost, or arrives damaged, you're covered under our Refund & Replacement Policy.
We accept Visa, Mastercard, and American Express. Apple Pay and Google Pay are available upon request via your account manager.
All transactions are processed through a secure, PCI DSS–compliant system to ensure your data is fully protected.
Why Choose NOVERA COMPOUNDS Peptides?
Novera Research delivers high-quality research peptides developed under strict manufacturing and quality-control standards. Each product is carefully synthesized, tested, and handled to ensure consistency, reliability, and transparency for advanced research applications.
High-purity, research-grade peptide synthesis
Analytical testing to verify quality and composition
Consistent batch-to-batch performance
Batch identification on every vial for traceability
Stored and shipped under controlled conditions
Why Choose Medica Depot
Shop hundreds of medical products with no minimums and free shipping on large orders.
INFORMATION
What is Mazdutide (10 mg)?
Mazdutide (10 mg) is a synthetic investigational peptide. It is a dual GLP-1R/GCGR agonist (investigational) used in research to study metabolic hormone signaling. In laboratory experiments, Mazdutide is examined for its interactions with receptors that regulate glucose, fat metabolism, and overall energy balance.
The peptide includes specific amino acid changes and a lipidated side chain, which helps extend its effects by increasing plasma protein binding in research models. These modifications allow researchers to study longer-lasting receptor activation and its effects compared to shorter-acting peptide versions. Mazdutide is commonly used in research on hormone signaling, insulin sensitivity, and energy metabolism.
Mazdutide (10 mg) is provided as a high-purity lyophilized powder to ensure consistent results in laboratory studies. It is for research purposes only and not intended for medical or diagnostic use.
Product Specifications
- CAS Number: 2259884-03-0
- Peptide Sequence:
His–Aib–Gln–Gly–Thr–Phe–Thr–Ser–Asp–Tyr–Ser–Lys–Tyr–Leu–Asp–Glu–Lys–Lys–Ala–Lys–(AEEA–AEEA–γGlu–Nonadecanoic acid)–Glu–Phe–Val–Glu–Trp–Leu–Leu–Glu–Gly–Gly–Pro–Ser–Ser–Gly–NH₂ - Molecular Formula: C₂₁₀H₃₂₂N₄₆O₆₇
- Molecular weight: 4563.06 g/mol
- Synonyms: IBI-362, LY-3305677
- Purity: ≥95% (verified by HPLC and mass spectrometry)
- Packaging Format: 10 mg lyophilized powder in a sealed research vial
- Storage Conditions: Store at 2–8 °C or frozen at ≤ –20 °C as appropriate. Protect from light and moisture
- Intended Use: For Laboratory Research Use Only
Key Characteristics of Mazdutide (10 mg)
- Synthetic long-acting metabolic peptide analog
- Lipidated structure designed to enhance protein binding in research models
- Studied for multi-receptor engagement in glucose and energy signaling pathways
- High analytical purity confirmed via HPLC and mass spectrometry
- Lyophilized formulation supports stability and consistent reconstitution
- Suitable for in vitro assays and preclinical metabolic research frameworks
- Compatible with controlled endocrine and receptor-binding experimental models
How Mazdutide (10 mg) Supports Research
Mazdutide (10 mg) is used in research to study how the peptide influences metabolic regulation. Researchers focus on how it interacts with hormone receptors related to glucose control and energy balance. Its design allows scientists to observe how the peptide activates receptors and causes changes inside cells.
Because Mazdutide has extended-acting properties, it is especially useful in studies that compare long-term versus short-term exposure to peptides. It is typically used in laboratory models to explore receptor activation, insulin response, fat metabolism, and hormone signaling. All research applications are for investigational purposes and are conducted in controlled lab settings.
Research Applications & Usage Information
Mazdutide (10 mg) is commonly used in research for:
- Peptide–receptor interaction assays related to metabolic hormone signaling
- Glucose homeostasis and insulin-response research models
- Energy expenditure and adipose tissue signaling investigations
- Lipid metabolism and nutrient utilization studies
- Comparative analysis of long-acting versus short-acting metabolic peptides
- Preclinical endocrine signaling pathway characterization
- Pharmacodynamic and receptor-binding studies in controlled systems
These applications are restricted to in vitro and preclinical research settings.
Handling and Storage Recommendations
- Store unopened vials at 2–8 °C
- For long-term storage, maintain at ≤–20 °C
- Protect from light and moisture
- Allow vial to equilibrate before reconstitution to reduce condensation
- After reconstitution, store solutions at 2–8 °C
- Avoid repeated freeze-thaw cycles to preserve structural integrity
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Dong W, Bai J, Yuan Q, et al. Mazdutide, a dual agonist targeting GLP-1R and GCGR, mitigates diabetes-associated cognitive dysfunction: mechanistic insights from multi-omics analysis. EBioMedicine. 2025;117:105791. doi:10.1016/j.ebiom.2025.105791
- Han C, Sun Y, Yang Q, et al. Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease. Mol Pharm. 2021;18(8):2906-2923. doi:10.1021/acs.molpharmaceut.0c00995
- Cheng W, Chen Z, Li P, et al. Case Report: Efficacy and safety of dose-escalated Mazdutide, a GLP-1/GCGR dual agonist, in an adolescent with obesity, type 2 diabetes, and hyperuricemia. Front Endocrinol (Lausanne). 2025;16:1654506. Published 2025 Sep 15. doi:10.3389/fendo.2025.1654506
What is Mazdutide (10 mg)?
Mazdutide (10 mg) is a synthetic investigational peptide. It is a dual GLP-1R/GCGR agonist (investigational) used in research to study metabolic hormone signaling. In laboratory experiments, Mazdutide is examined for its interactions with receptors that regulate glucose, fat metabolism, and overall energy balance.
The peptide includes specific amino acid changes and a lipidated side chain, which helps extend its effects by increasing plasma protein binding in research models. These modifications allow researchers to study longer-lasting receptor activation and its effects compared to shorter-acting peptide versions. Mazdutide is commonly used in research on hormone signaling, insulin sensitivity, and energy metabolism.
Mazdutide (10 mg) is provided as a high-purity lyophilized powder to ensure consistent results in laboratory studies. It is for research purposes only and not intended for medical or diagnostic use.
Product Specifications
- CAS Number: 2259884-03-0
- Peptide Sequence:
His–Aib–Gln–Gly–Thr–Phe–Thr–Ser–Asp–Tyr–Ser–Lys–Tyr–Leu–Asp–Glu–Lys–Lys–Ala–Lys–(AEEA–AEEA–γGlu–Nonadecanoic acid)–Glu–Phe–Val–Glu–Trp–Leu–Leu–Glu–Gly–Gly–Pro–Ser–Ser–Gly–NH₂ - Molecular Formula: C₂₁₀H₃₂₂N₄₆O₆₇
- Molecular weight: 4563.06 g/mol
- Synonyms: IBI-362, LY-3305677
- Purity: ≥95% (verified by HPLC and mass spectrometry)
- Packaging Format: 10 mg lyophilized powder in a sealed research vial
- Storage Conditions: Store at 2–8 °C or frozen at ≤ –20 °C as appropriate. Protect from light and moisture
- Intended Use: For Laboratory Research Use Only
Key Characteristics of Mazdutide (10 mg)
- Synthetic long-acting metabolic peptide analog
- Lipidated structure designed to enhance protein binding in research models
- Studied for multi-receptor engagement in glucose and energy signaling pathways
- High analytical purity confirmed via HPLC and mass spectrometry
- Lyophilized formulation supports stability and consistent reconstitution
- Suitable for in vitro assays and preclinical metabolic research frameworks
- Compatible with controlled endocrine and receptor-binding experimental models
How Mazdutide (10 mg) Supports Research
Mazdutide (10 mg) is used in research to study how the peptide influences metabolic regulation. Researchers focus on how it interacts with hormone receptors related to glucose control and energy balance. Its design allows scientists to observe how the peptide activates receptors and causes changes inside cells.
Because Mazdutide has extended-acting properties, it is especially useful in studies that compare long-term versus short-term exposure to peptides. It is typically used in laboratory models to explore receptor activation, insulin response, fat metabolism, and hormone signaling. All research applications are for investigational purposes and are conducted in controlled lab settings.
Research Applications & Usage Information
Mazdutide (10 mg) is commonly used in research for:
- Peptide–receptor interaction assays related to metabolic hormone signaling
- Glucose homeostasis and insulin-response research models
- Energy expenditure and adipose tissue signaling investigations
- Lipid metabolism and nutrient utilization studies
- Comparative analysis of long-acting versus short-acting metabolic peptides
- Preclinical endocrine signaling pathway characterization
- Pharmacodynamic and receptor-binding studies in controlled systems
These applications are restricted to in vitro and preclinical research settings.
Handling and Storage Recommendations
- Store unopened vials at 2–8 °C
- For long-term storage, maintain at ≤–20 °C
- Protect from light and moisture
- Allow vial to equilibrate before reconstitution to reduce condensation
- After reconstitution, store solutions at 2–8 °C
- Avoid repeated freeze-thaw cycles to preserve structural integrity
Research Use Only Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Dong W, Bai J, Yuan Q, et al. Mazdutide, a dual agonist targeting GLP-1R and GCGR, mitigates diabetes-associated cognitive dysfunction: mechanistic insights from multi-omics analysis. EBioMedicine. 2025;117:105791. doi:10.1016/j.ebiom.2025.105791
- Han C, Sun Y, Yang Q, et al. Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease. Mol Pharm. 2021;18(8):2906-2923. doi:10.1021/acs.molpharmaceut.0c00995
- Cheng W, Chen Z, Li P, et al. Case Report: Efficacy and safety of dose-escalated Mazdutide, a GLP-1/GCGR dual agonist, in an adolescent with obesity, type 2 diabetes, and hyperuricemia. Front Endocrinol (Lausanne). 2025;16:1654506. Published 2025 Sep 15. doi:10.3389/fendo.2025.1654506




