DEPO-PROVERA®

DEPO-PROVERA® Product Description

DEPO-PROVERA® is an injectable contraceptive containing medroxyprogesterone acetate, a synthetic hormone similar to natural progesterone. It is designed to prevent pregnancy, treat endometriosis, and manage specific cancers. The product is only available with a doctor’s prescription.

Key uses include:

• Contraception: Provides protection for up to 3 months per injection.
• Endometriosis: Reduces the growth of uterine lining cells outside the uterus.
• Cancer Management: Used for breast, kidney, and endometrial cancer treatment.

DEPO-PROVERA® Key Features and Benefits

This injectable solution offers a convenient and effective alternative to other contraceptives and treatments. Its key features include:

• Long-lasting efficacy with one injection every three months for contraception.
• Effective hormone regulation to address endometriosis symptoms.
• Reduction of cancer cell growth in specific cases.

DEPO-PROVERA® Indications and Treatment Applications

DEPO-PROVERA® is indicated for:

• Women seeking long-term contraception.
• Management of endometriosis-related pain and bleeding.
• Treatment of hormone-responsive cancers such as breast and kidney cancer.

DEPO-PROVERA® Dosage and Administration

The dosage depends on the indication:

• Contraception: 150 mg injected into the buttock muscle every 3 months.
• Endometriosis: 50 mg weekly or 100 mg every two weeks for at least 6 months.
• Cancer Treatment:
  • Initial dose: 500-1200 mg weekly.
  • Maintenance dose: 450-600 mg every 1-4 weeks.

Important guidelines:

• For contraception, the first injection should occur during the first 5 days of the menstrual cycle or postpartum.
• Maintain a strict schedule to ensure consistent contraceptive protection. 

DEPO-PROVERA® Side Effects and Warnings

Like all medications, DEPO-PROVERA® has potential side effects. Common side effects include:

• Changes in menstruation: Irregular periods or absence of menstruation.
• Bone density reduction: Prolonged use can lead to osteoporosis.
• Weight changes: Weight gain or loss is possible.
• Mood disturbances: Nervousness, depression, or fatigue.
• Physical reactions: Acne, hair thinning, or breast tenderness.

Serious side effects requiring immediate medical attention:

• Allergic reactions: Swelling, rash, or difficulty breathing.
• Blood clots: Painful swelling in the legs or chest tightness.
• Severe abdominal pain.

DEPO-PROVERA® Precautions and Contraindications

DEPO-PROVERA® should not be used by individuals with:

• History of blood clots or strokes.
• Liver disease or undiagnosed vaginal bleeding.
• Allergy to medroxyprogesterone acetate or other ingredients.
• Current or suspected pregnancy.

Caution is advised for:

• Women under 18 due to bone density concerns.
• Patients with conditions like diabetes, migraines, or kidney disease.

DEPO-PROVERA® Long-Term Considerations

Prolonged use may increase the risk of osteoporosis, especially in younger women. Calcium levels in bones usually recover after stopping the medication, but this may not be complete in all cases.

DEPO-PROVERA® Storage and Handling

• Store in a cool, dry place below 30°C.
• Avoid exposure to heat or direct sunlight.
• Keep out of reach of children.

DEPO-PROVERA® Manufacturer and Regulatory Information

DEPO-PROVERA® is manufactured by Pfizer Australia Pty Ltd. The product is a registered trademark and complies with regulatory standards. For more information, contact Pfizer at 1800 675 229 or visit their website.

DEPO-PROVERA® FAQs

What is the recommended schedule for contraception injections?

The injection should be administered every 3 months. Timely follow-ups are essential to maintain contraceptive efficacy.

Does DEPO-PROVERA® protect against sexually transmitted infections (STIs)?

No, DEPO-PROVERA® does not provide protection against STIs. Safe sex practices, including condom use, are recommended.

What should I do if I miss an injection?

If more than 14 weeks have passed since the last injection, consult your doctor for a pregnancy test before resuming treatment.

Is it possible to conceive after stopping DEPO-PROVERA®?

Yes, most women regain fertility within 12-18 months after the last injection. This timeline is not affected by the length of DEPO-PROVERA® use.

Are there dietary considerations while using DEPO-PROVERA®?

Ensure adequate intake of calcium and vitamin D to mitigate bone density loss, especially with long-term use.

Can DEPO-PROVERA® be used during breastfeeding?

Yes, but only 6 weeks postpartum, after confirming the absence of pregnancy.