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BOTULAX 100U KOREAN 01
BOTULAX 100U KOREAN 02
BOTULAX 100U KOREAN 03
BOTULAX 100U KOREAN 04
KFDA Approved EU Approved
BOTULAX®

BOTULAX® (LETYBO®) 100u (Korean)

Manufacturer: Hugel Pharma
Active Substance(s) : BOTULINUM TOXIN TYPE A
Strength: 100u
Pack Size: 1 x 100u Vial (Powder)
Accessories: Package insert
BOTULAX® is a peripheral muscle relaxant that contains purified botulinum toxin type A (in combination with haemagglutinin) and sodium chloride (excipient). The mechanism of action of the product is based on the ability of botulinum toxin type A to block the transmission of nerve impulses. Intramuscular administration of the toxin disrupts the synthesis of acetylcholine (a neurotransmitter that ensures neuromuscular conduction) and leads to temporary paralysis of the facial muscles. Frozen facial expressions help relax muscles and smooth wrinkles.Anti-wrinkle treatment to be used for nasolabial folds, hyperhidrosis, lip contouring, and overall natural face lifting

Toxin products

Vial may appear empty, which is normal. Toxins come as concentrated freeze-dried powder which looks like a transparent film at the bottom of the vial. This product must be reconstituted with saline before use.

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INFORMATION

BOTULAX® 100u (Korean) Key Features and Benefits

BOTULAX® 100u is a botulinum toxin type A product manufactured by Hugel Pharma, designed to provide effective treatment with stability and high quality. It is commonly used in the aesthetic and medical markets, offering a cost-effective solution.

  • Key Benefits:
    • High potency maintained through strict quality control.
    • Affordable pricing for premium-grade botulinum toxin.
    • Stable potency after reconstitution for efficient use.
    • Tailored to the needs of aesthetic professionals.

BOTULAX® 100u (Korean) Reconstitution Chart

Reconstitution involves dissolving freeze-dried BOTULAX® 100u in sterile saline. Accurate reconstitution ensures optimal product performance.

  • Dilution Recommendations:
    • Reconstitute with 0.9% Sodium Chloride Injection.
    • Use within 24 hours post-reconstitution.
    • Store at 2–8°C after preparation.

BOTULAX® 100u (Korean) Storage Information

Proper storage of BOTULAX® 100u is critical to maintain its efficacy and safety.

  • Storage Guidelines:
    • Keep at 2–8°C in a hermetically sealed container.
    • Avoid freezing or exposing to direct sunlight.
    • Expiry: 24 months from the manufacturing date.

BOTULAX® 100u (Korean) Treatment Areas

BOTULAX® 100u is indicated for treating specific facial and muscular conditions through targeted injections.

  • Primary Applications:
    • Glabellar lines.
    • Blepharospasm.
    • Essential muscular conditions requiring relaxation.

BOTULAX® 100u (Korean) Dosing for Different Indications

Dosage varies based on the treatment area and patient requirements. Physicians should use the lowest effective dose.

  • Dosing Guidelines:
    • Typical initial dose: 1.25–2.5 units per site.
    • Maximum dose in a 30-day period: 200 units.
    • Use fine needles (27–30 gauge) for injections.

BOTULAX® 100u (Korean) Side Effects and Precautions

While effective, BOTULAX® 100u may cause mild to moderate adverse reactions. Proper administration minimizes risks.

  • Common Side Effects:
    • Localized pain or swelling at the injection site.
    • Temporary muscle weakness.
    • Mild bruising or erythema.
  • Precautions:
    • Avoid in patients with known hypersensitivity to botulinum toxin or formulation components.
    • Not recommended for pregnant or breastfeeding women.
    • Caution in patients with neuromuscular disorders.

BOTULAX® 100u (Korean) Aftercare

Post-treatment care ensures the safety and longevity of the results.

  • Aftercare Tips:
    • Avoid strenuous activity for 24 hours post-treatment.
    • Do not massage or rub the treated area for at least 4 hours.
    • Keep upright for 4 hours after injection to prevent toxin migration.

BOTULAX® 100u (Korean) Drug Interactions

Certain medications may interact with BOTULAX® 100u, influencing its effects.

  • Potential Interactions:
    • Aminoglycoside antibiotics may potentiate the effects.
    • Muscle relaxants or anticholinergic drugs may increase the risk of adverse reactions.
    • Consult with a physician regarding current medications before administration.

BOTULAX® 100u (Korean) Key Features and Benefits

BOTULAX® 100u is a botulinum toxin type A product manufactured by Hugel Pharma, designed to provide effective treatment with stability and high quality. It is commonly used in the aesthetic and medical markets, offering a cost-effective solution.

  • Key Benefits:
    • High potency maintained through strict quality control.
    • Affordable pricing for premium-grade botulinum toxin.
    • Stable potency after reconstitution for efficient use.
    • Tailored to the needs of aesthetic professionals.

BOTULAX® 100u (Korean) Reconstitution Chart

Reconstitution involves dissolving freeze-dried BOTULAX® 100u in sterile saline. Accurate reconstitution ensures optimal product performance.

  • Dilution Recommendations:
    • Reconstitute with 0.9% Sodium Chloride Injection.
    • Use within 24 hours post-reconstitution.
    • Store at 2–8°C after preparation.

BOTULAX® 100u (Korean) Storage Information

Proper storage of BOTULAX® 100u is critical to maintain its efficacy and safety.

  • Storage Guidelines:
    • Keep at 2–8°C in a hermetically sealed container.
    • Avoid freezing or exposing to direct sunlight.
    • Expiry: 24 months from the manufacturing date.

BOTULAX® 100u (Korean) Treatment Areas

BOTULAX® 100u is indicated for treating specific facial and muscular conditions through targeted injections.

  • Primary Applications:
    • Glabellar lines.
    • Blepharospasm.
    • Essential muscular conditions requiring relaxation.

BOTULAX® 100u (Korean) Dosing for Different Indications

Dosage varies based on the treatment area and patient requirements. Physicians should use the lowest effective dose.

  • Dosing Guidelines:
    • Typical initial dose: 1.25–2.5 units per site.
    • Maximum dose in a 30-day period: 200 units.
    • Use fine needles (27–30 gauge) for injections.

BOTULAX® 100u (Korean) Side Effects and Precautions

While effective, BOTULAX® 100u may cause mild to moderate adverse reactions. Proper administration minimizes risks.

  • Common Side Effects:
    • Localized pain or swelling at the injection site.
    • Temporary muscle weakness.
    • Mild bruising or erythema.
  • Precautions:
    • Avoid in patients with known hypersensitivity to botulinum toxin or formulation components.
    • Not recommended for pregnant or breastfeeding women.
    • Caution in patients with neuromuscular disorders.

BOTULAX® 100u (Korean) Aftercare

Post-treatment care ensures the safety and longevity of the results.

  • Aftercare Tips:
    • Avoid strenuous activity for 24 hours post-treatment.
    • Do not massage or rub the treated area for at least 4 hours.
    • Keep upright for 4 hours after injection to prevent toxin migration.

BOTULAX® 100u (Korean) Drug Interactions

Certain medications may interact with BOTULAX® 100u, influencing its effects.

  • Potential Interactions:
    • Aminoglycoside antibiotics may potentiate the effects.
    • Muscle relaxants or anticholinergic drugs may increase the risk of adverse reactions.
    • Consult with a physician regarding current medications before administration.

Frequently Asked Questions

BOTULAX® is a botulinum toxin injection indicated for the temporary improvement of moderate to severe glabellar lines in individuals aged between 18 and 65. In pediatric cerebral palsy patients aged two or older, Botulax can be used for the treatment of dynamic equinus foot deformity due to spasticity.

Superior stability after reconstitution: This product exhibits superior stability on the condition of cold/freezer storage after reconstitution.
Highly potent: Botulax demonstrates excellent potency, thanks to the manufacturing process.

1 transparent glass vial containing white injectable dry powder
Package insert

BOTULAX® has inhibitory effects on neuromuscular transmission. It cleaves a protein called SNAP-25 to stimulate the release of Ach.

100 units (U) of Clostridium Botulinum Toxin A type (derived from Clostridium Botulinum CBFC26 strain)
0.5 mg of human serum albumin
0.9 mg sodium chloride

In clinical trials, BOTULAX® can last from 120 to 130 days. Its duration of action is about the same as that of Botox.

BOTULAX® generally requires minimal recovery time, as it is administered via a minimally-invasive injection.

Ensure that BOTULAX® is sealed. Do not use this product if the seal has been broken.
To ensure the potency of its active ingredient, BOTULAX® should be stored at a temperature of 2 to 8 degree Celsius in a hermetic container. Improper storage method may shorten the shelf life of BOTULAX®. Check the expiration date prior to using BOTULAX®. Do not use if the product has expired (i.e., 24 months after the manufacturing date). It is advisable to use BOTULAX® within a day on reconstitution.
BOTULAX® is intended for professional use only. Patients must not attempt to self-administer BOTULAX®. Doctors administering Botulax should understand the orbital and/or neuromuscular anatomy of the treatment area, as well as any anatomical alternations due to a previous surgical procedure.
Do not use this product in patients with known allergy to any component of the formulation, or for that matter, those with neuromuscular junctional disorders. This include amyotrophic laternal sclerosis, Lambert-Eaton syndrome and myasthenia gravis. Be aware that Botulax is contraindicated for use during pregnancy or breastfeeding.

Asthenia
Diplopia
Generalized muscle weakness
Dysphagia
Ptosis
Dysarthria
Dysphonia
Breathing difficulties
Urinary incontinence

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