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Treatment for deep wrinkles and lip augmentation
$139.00 / pack
(you save $0)
Quantity Our Price
1 - 5 pack(s) $139.00 USD
6 - 10 pack(s) $135.00 USD
11 - 20 pack(s) $132.00 USD
21+ pack(s) USD$130.00 130.00USD
Manufacturer: Merz Pharmaceuticals
Active Substance(s) : Hyaluronic acid, mannitol
Strength: 24mg/ml
Pack Size: 2-1ml prefilled syringes
Accessories: Package insert, 2-27G 1/2" needles, 2-25G 1" needles, 4 traceability labels

What is Etermis 4?

Etermis 4 is an injectable gel used for correcting deep wrinkles and for lip augmentation. Its hyaluronic acid content attracts moisture within the skin to restore volume, while its mannitol acts as a protective antioxidant. This gel is suitable for use on the lips or aging skin.

Where can I buy this product?

Licensed medical practitioners may buy Etermis 4 at wholesale prices from Medica Depot. Place an order today either through our website at, or contact 1 of our friendly customer care specialists by phone. Simply sign up for a free account, and you can start ordering Etermis 4 and other aesthetic injectables once your account is verified.

What does this product come with?

Each box includes:

  • 2 prefilled 1ml syringes;
  • 2-27G1/2” needles;
  • 2-25G1” needles;
  • And 1 packaging insert.

What are the benefits of this product?

This highly versatile treatment is suitable for treating a wide range of cosmetic concerns related to skin aging, including skin depressions. It is also suitable for providing volume to the upper and lower lips. This formula also includes the antioxidant mannitol, which is added to preserve the action of hyaluronic acid in the skin tissue. Made with high-quality ingredients, Etermis 4 boasts an excellent safety profile as well as natural, noticeable, and long-lasting results.

How does this product work?

Etermis 4 treats the signs of aging associated with facial volume loss by plumping the skin. Etermis 4 has the highest viscosity gel all fillers in the Etermis range, making it suitable to treat facial volume loss effectively and with natural-looking results.

What are the ingredients?

Etermis 4 contains 24mg/ml of hyaluronic acid, a sodium phosphate buffer of pH 7.1, and mannitol.

Use Instructions

How to inject/administer this product

This procedure should only be carried out by a legally licensed medical practitioner who is trained in dermal filling.

Prior to treatment, brief the patient on the product’s indications, contraindications, incompatibilities, and potential side effects. To administer this product, prepare the syringe by attaching the needle to the syringe tip securely, as per the manufacturer’s instructions. Thoroughly sanitize the treatment area with a suitable antiseptic. Inject the product slowly into the mid to deep dermis using the appropriate injection technique (linear threading, fanning, cross-hatching, serial puncture, or sandwich injection techniques will work). An alternative method of administration is to use a cannula. After injection, massage the treated area gently to ensure that the product is evenly distributed. Review all precautions, contraindications, and use instructions prior to treatment.

When should I use this product?

Etermis 4 can be used to correct deep and severe wrinkles such as nasolabial folds and marionette lines, as well as to enhance the lips. Correction using this product can be performed in 1 or 2 injection sessions, after which maintenance treatments once every year are necessary to perpetuate the effects.

What areas can I treat with this product?

Etermis 4 is indicated for areas of the face that require correction of deep and severe wrinkles, such as marionette lines. It may also be used to elevate the mouth corner and volumize the upper and lower lips.

How long do results last?

The results of an Etermis 4 treatment will likely last up to 1 year, depending on the patient’s age, gender, and skin quality, among other factors. To extend the benefits, maintenance treatments need to be performed.

Frequently Asked Questions

Who is an ideal candidate for this product?

Patients who will benefit from an Etermis 4 treatment are those afflicted with the loss of volume in their facial features. As well, this product is also suitable for the enhancement of the lips. This product is not suitable for patients who are hypersensitive to hyaluronic acid or mannitol, for children under 18 years of age, and for women who expecting or lactating.

Why should I purchase this product?

Etermis products function as highly adaptable, versatile fillers that are able to cater to a wide range of patients. As a monophasic, highly cohesive product, Etermis 4 provides extremely natural-looking—and noticeable—results. Manufactured by a reputable company, the Etermis range of products has low extrusion force, is well-tolerated, and boasts a low rate of adverse events.

Are there any side effects?

Treatment with Etermis 4 may result in erythema, edema, swelling, or pain after injection. In some cases, itching or burning sensations, as well as irritation, tenderness, or tingling sensations may also be experienced. Rare and serious adverse effects include nodule formation, hypersensitivity, and infection. Any side effect that persists for longer than 1 week should be brought to your attention immediately. Educate your patient on all of the precautions and contraindications to ensure they are suitable for treatment. This is not a complete list of side effects. All side effects can be found listed in the product pamphlet.

*This website offers only genuine products made by their original manufacturer. All brands are trademarks of their respective owners. This website is not operated by, supported by, or affiliated with the manufacturer in any way. Product packaging may not be exactly as shown.

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