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Etermis

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Etermis is an injectable dermal filler range that is comprised of 3 cohesive, monophasic, hyaluronic acid-based cosmetic fillers infused with mannitol. Being an antioxidant, mannitol protects against free radicals, ultimately inhibiting the degradation of the hyaluronic acid when the filler is introduced to the skin. This filler line offers solutions to fine to severe lines and wrinkles.

Hyaluronic acid is a naturally occurring sugar found in the body that ensures retains moisture and promotes optimal skin health. Etermis restores the volume of the dermal tissues, giving a more supple and flawless complexion.

What makes a good candidate?

Etermis’ filler range can be administered to both male and female patients looking to reduce signs of aging.

The use of Etermis is contraindicated in:

  • patients taking anticoagulants;
  • pregnant or breastfeeding patients;
  • children;
  • patients with a history of hypertrophic scars or keloid scars;
  • patients with skin infections or inflamed skin;
  • patients with a known allergy to any of the fillers’ components.

Ensure to review the medical history of your patient to avoid complications.

Areas treated with Etermis

Etermis 2 is suitable for patients seeking treatment of delicate areas showing signs of mild or superficial wrinkles.

Etermis 3 is used to treat moderate wrinkles and to enhance the lips.

Etermis 4 is used to smooth out deep wrinkles and can be used to increase lip volume.

Use Etermis for:

  • Nasolabial folds
  • Marionette lines
  • Philtrum columns
  • Upper and lower lips
  • Corners of the mouth
  • How does Etermis work

Etermis dermal fillers contain hyaluronic acid, which attracts and holds moisture in the skin. This helps to increase volume and smooth out lines and wrinkles. As well, the added mannitol helps protect against free radicals and increases the duration of the fillers’ effects.

Treatment details

Discuss potential side effects with your patient, as well as any contraindications and precautions. Ensure the product is at room temperature. You should also check the packaging to ensure that there is no any damage to the filler and it is not expired.

Disinfect the treatment area using an antiseptic. You can use an anesthetic, if desired. Slowly inject the product according to the instructions listed in their respective product pamphlets. You can use sandwich, fanning, serial puncture, cross-hatching, or linear threading injection techniques. The amount to administer depends on the area to be corrected. After the injection, massage the treated area in order to facilitate even distribution of the product.

Properly dispose of any used or opened needles and syringes.

How long does Etermis last?


Etermis dermal fillers have the added benefit of mannitol. This antioxidant not only promotes healthy skin by fighting off free radicals, but it also increases the duration of the results. On average, the effects last for up to a year before the hyaluronic acid is absorbed into the surrounding tissues. The results may be affected by the patient’s skin condition, age, and lifestyle. To maintain a youthful complexion, schedule your client for follow up treatments once a year or as needed.

Safety information

Etermis boasts an excellent safety profile, with good tolerability and a low rate of adverse effects.


Although generally well-tolerated, some patients may experience mild, injection-related side effects.

These are the most common side effects the patient might experience after administration of the filler:

  • inflammation, swelling, pain or redness;
  • bruising or bleeding;
  • Tyndall effect, if injected too superficially;
  • Burning or itching sensation.

Some rare side effects may occur, including necrosis, hyperpigmentation, or hypersensitivity. In case of any adverse events, advise the patient to seek immediate medical attention.
Common side effects usually resolve themselves within a week after the injection. Should these effects last longer, advise your patient to seek medical attention.
For a full list of side effects, contraindications, and precautions, refer the product leaflet.

Recovery time

Etermis cosmetic filler treatments do not require any downtime. Immediately after treatment, your client should be able to resume their regular routine. For the first 12 hours after the treatment, your patient should not apply makeup. As well, they should avoid extreme temperatures, including prolonged sun exposure, saunas, and cold temperatures.

Cost of Etermis

The cost of dermal filler treatments is determined by the amount used and the number of areas being treated. On average, clients can expect to pay $550 or more for aesthetic injectables. You can determine the cost of Etermis in your clinic based on the aforementioned factors.

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