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synvisc vs euflexxa image comparison
Synvisc (hylan G-F 20) is the brand name for the high-molecular-weight injectable fluid that contains both hylan A and hylan B polymers. The polymers in Synvisc, like most hyaluronic derivatives, are derived from rooster combs and are classified as avian-derived hyaluronic acid (AV-HA). Euflexxa, on the other hand is made from a very highly purified product extracted from bacterial cells. It is a polysaccharide consisting of a repeating disaccharide of N-Acetylglucosamine and sodium glucuronate that are linked by glycosidic bonds. While Supartz, Synvisc, and other AV-HA brands are similar in their efficacy, Synvisc offers a one-dose treatment that prevents multiple trips to a doctor’s office. According to the National Institute of Health, AV-HA treatments all appear to relieve pain for between 4 and 14 weeks by restoring both mechanical and biomechanical homeostasis in the joint. A difference in price gives Euflexxa a bit of an edge. At present, Euflexxa is about 20% cheaper [Read more]
Orthovisc vs Synvisc: Knee osteoarthritis Treatment
Viscosupplements Viscosupplementation addresses the diminished amount of hyaluronic acid in synovial fluid by supplementing the degraded synovial fluid in the diseased joint with a hyaluronic acid product that possesses the rheological properties of healthy synovial fluid. These medications are normally offered as second-line therapies, which are treatments that are used after the patient has not adequately responded to primary treatments such as pain medication and physical therapy. Viscosupplement preparations differ significantly in their molecular weight, concentration, rheological properties, manufacturing processes, and residence times in the joint. The effects that viscosupplements confer are delayed but long-lasting. While it can sometimes take weeks or even several months for the full results of viscosupplements like Orthovisc and Synvisc to materialize, these medications can provide up to six months of improvement, including reduced pain and a greater range of motion. [Read more]
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