A woman gets an injection of Xeomin in glabellar lines from a doctor which explains the usage and dosage

Guide to Xeomin: Purchasing Online, Usage, Dosage, Administration & More

Where to Buy Xeomin

Xeomin is available for purchase from Medica Depot and similar online stores. Simply select your desired quantity, submit a mailing address, provide payment details and verify your medical license information.

While buying Xeomin online is not difficult, finding the best deals when ordering supplies for your medical practice can be time consuming. Price is important but product quality must also be taken into consideration.

While authentic Xeomin contains a specific quantity of botulinum toxin, this may not be the case if you unknowingly order a counterfeit product. Avoid those scams and save time by letting our purchasing agents point you to the best deals available online for authentic Xeomin.

Helpful Information to Consider

What’s in the box?

Product Name: Xeomin
Active Composition: Clostridium Botulinum neurotoxin type A (150kD), free from complexing proteins
Form & Contents: One vial. It contains 100 LD50 units powder for solution for injection.
Manufacturer: Merz Pharmaceutical GmbH
Origin: Europe
Accessory: Package leaflet only.
Storage Conditions: Keep out of reach and sight of children. Do not store above 25 ℃.
Note: Sterile packaging.

Why use this product?

Xeomin is an injectable that relaxes the muscles. It is used for treatment of a range of conditions in adults, including eyelid spasms, twisted neck, and increased muscle tension/uncontrollable muscle stiffness in arms or hands after a stroke.

Xeomin is reconstituted prior to use with sodium chloride 9 mg/ml (0.9%) solution for injection. It may only be used by health care professionals experienced in the application of botulinum toxin. The optimum dosage and number of injection sites in the treated muscle will be chosen by the doctor. Due to differences in the LD50 assay, these units are specific to Xeomin and are not applicable to other botulinum toxin preparations.

Can I buy Xeomin without a medical license?

Xeomin should not be purchased without a medical license. Websites offering to sell Xeomin and similar products to individuals without requiring proper documention are disreputable and can put your practice at risk. The use of Xeomin is restricted to medical professionals and it should not be self-injected.

Additional Information 

What is Xeomin?

Xeomin is a medication that contains botulinum toxin type A and is indicated for the treatment of blepharospasm (eyelid spasms), spasmodic torticollis (twisted neck), and upper limb spasticity. As an inhibitor of the neurotransmitter acetylcholine, this neurotoxin temporarily relaxes the muscles involved in neuromuscular disorders by preventing the muscle fibers from receiving nerve transmission. This injectable is clinically proven to be a safe, effective and durable treatment.

Patients who have a history of hypersensitivity to botulinum toxin or to any of the other components of Xeomin should not be treated with it. Do not inject it into infected skin and do not use this medication in nursing or pregnant women. The safety profile of this product has not yet been established in patients below 18 years of age.

How does Xeomin work?

Movement disorders arise as a result of neurological conditions that cause increased abnormal movement. These conditions are often painful and debilitating. The types of movement disorders Xeomin can treat include spasmodic torticollis, a condition involving spasms or contractions of the neck muscles that cause abnormal head movement; blepharospasm, a condition where there is involuntary contraction or twitching of the eyelid; and upper limb spasticity, which refers to muscle stiffness in various regions in the upper limb, such as flexed elbow or wrist, clenched fist, pronated forearm, thumb-in-palm, or rotated/adducted/extended, to name a few.

Intended for intramuscular injection only, Xeomin alleviates symptoms of these disorders by acting on the nerves of the muscles involved in the abnormal movement to temporarily cease muscle contractions underneath the treatment area. This product is made of a neurotoxin isolated from the bacterium clostridium botulinum that acts on nerve endings to prevent the release of acetylcholine, a neurotransmitter. This action effectively stops nerve signaling in the affected area, resulting in paralysis. This effect is temporary, and will gradually cease once signaling is re-established by the formation of new nerve endings.

Treatment details & dosing

Only an authorized medical practitioner with specialist knowledge of treatment with botulinum neurotoxin type A may administer this treatment.

Prior to treatment, fully inform your prospective patient on the associated indications, contraindications, precautions, and potential adverse events. Take down a complete medical history of the patient before proceeding.


Xeomin must be reconstituted prior to intramuscular injection. Reconstitute Xeomin with 0.9% sodium chloride solution.


The optimum dose, frequency, and number of injection sites in the treated muscle should be tailored to the individual patient. The results of initial treatment with Xeomin should be evaluated and dosage adjustment may be required to achieve the desired therapeutic effect.

Recommended starting doses for each indication are as follows:

  • Twisted neck (spasmodic torticollis): Up to 50 units per injection site, up to a maximum dose of 200 units in the first treatment session. Doses of up to 300 units may be given in subsequent courses depending on response. Usually, the first onset of effect is observed within 7 days of injection.
  • Spasticity of the upper limb: Up to 500 units per treatment session, with no more than 250 units administered to the shoulder muscles. Patients reported the onset of action as being 4 days after treatment. An improvement of muscle tone is usually perceived within 4 weeks.

How long does Xeomin last?

The duration of effect of Xeomin varies by indication:

  • Blepharospasm: Up to 4 months. Treatment can be repeated if required.
  • Spasmodic torticollis: Up to 4 months. Treatment intervals of less than 12 weeks are not recommended.
  • Upper limb spasticity: Typically 12 weeks. The period between treatment sessions should be a minimum of 12 weeks.

Safety information: side effects and precautions

Xeomin is made via a state-of-the-art manufacturing process that minimizes the quantity of accessory or complexed proteins. As a result, this toxin is less prone to triggering immunogenic reactions in the patient, which in turn increases the success rate of repeat treatment.

As with all medications, injection with this product may cause unintended side effects. Advise your patient to seek medical attention immediately if he or she experiences an allergic reaction. Swallowing difficulties and excessive muscle weakness are other side effects that may occur when Xeomin acts to relax muscles in sites distal to the injection site. This is more likely to happen when using Xeomin to treat spasmodic torticollis.

The most common side effects observed with Xeomin treatment are mild inflammatory reactions at the site of injection, which may include:

  • Redness
  • Itching
  • Edema
  • Bruising at the site of injection

These reactions are typically not severe and will spontaneously resolve within a week.

Other side effects may be associated with a specific indication. Refer to the product pamphlet for a complete list of possible reactions.

Recovery time

There is no recovery time associated with botulinum toxin injections. Patients may resume their daily activities immediately following a treatment session.

Cost of Xeomin

In the United States, a Xeomin injection typically costs an average of $450. The price varies depending on the number of units administered.

The box of Bocouture 100 Units for buying online with the Best Wholesale Prices

Buy Bocouture Online: Best Wholesale Prices – Help & Guide

Botulinum Toxins, Cosmetic Treatments / By  Medical Community

10 Jul

Where to buy Bocouture?

You can buy Bocouture, also known as Xeomin, online through online retailers and also from brick and mortar authorized merchants. Buying online can be more convenient and save you time. Shopping online usually requires you to simply select the strength and quantity you want to purchase, submit your medical license number, complete payment and provide a mailing address. Buying online has become more popular among medical practitioners since it allows them to focus on their practice and manage their supply inventory better.

Need help finding Bocouture or another product?

If you cannot find what you need in our extensive product catalog, we can help source any medical or aesthetic product for you.
Simply use our product request form or  speak to one of our expert purchasing agents and start saving today!

What is Bocouture?

Also known as Xeomin or Xeomin Aesthetic, this is a cosmetic injectable made of botulinum toxin type A—similar to Botox and Dysport, but with units that are not equivalent. The botulinum toxin comes from the Clostridium botulinum bacterium, known for causing the illness botulism, but this neuromodulator is beneficial in small quantities. It temporarily paralyzes muscles, which relaxes wrinkles or treats certain medical conditions. Unlike its rival neurotoxins, this brand is free of complexing proteins, which the manufacturer claims makes it less likely to trigger antibodies. The lack of these complexing proteins helps to maintain the treatment’s effectiveness over time. Available in 50 units and 100 units, this neuromodulator comes in a powder ready for reconstitution using saline solution. Botulinum toxins such as this are the most popular minimally-invasive cosmetic treatments, used in millions of injections each year in the U.S. alone.

What makes a good candidate for this treatment?

Only patients over the age of 18 are suitable candidates for these cosmetic treatments. Although most mature patients wait until wrinkles are visible, patients in their 20s and 30s now choose these injections to help prevent future wrinkles. Since these injections work by relaxing muscles before wrinkles have the chance to form, doctors can offer this as wrinkle-prevention treatments. Doctors may also use this injectable for medical uses, targeting muscle spasms. This injectable is usually not suitable for use during pregnancy or breastfeeding, if the patient has a nerve or muscle disorder, or if the patient has a bleeding disorder.

Areas treated with Bocouture:

Doctors use this injectable to target muscles underlying wrinkles or other medical conditions. These uses can include:

• Glabellar lines, which are vertical frown lines between eyebrows;

• Horizontal frown lines between the eyebrows;

• Crow’s feet, which are lateral periorbital lines;

• Blepharospasm, which is involuntary muscle contractions around the eyes;

• Cervical dystonia, with neck spasms causing an abnormal head position;

• Upper limb spasticity;

• Other wrinkles caused by facial expressions and other medical conditions.

How does Bocouture work?

Botulinum toxin A is a natural neuromodulator that acts on nerves. The neurotoxin helps block the release of acetylcholine, so the nerves are unable to signal muscles to move. Without this signal to move, the muscles remain in a paralyzed position temporarily. They are then unable to spasm, in the case of medical conditions, and are unable to fold the skin to produce wrinkles. Since certain wrinkles are caused by repeated muscle movements, temporarily preventing these movements will temporarily smooth the wrinkles.

Treatment details

Before using this cosmetic injectable, you must reconstitute the powder with saline solution, obtaining an appropriate concentration for your needs. Clean the target area using an antiseptic, and if desired, apply an anesthetic. Then, inject the solution directly into the muscle or muscles targeted, possibly with multiple injections in the same area. The procedure should usually last less than 30 minutes, allowing your patients to return to their usual activities immediately.

How long does Bocouture last?

After an injection, patients usually see results as soon as 2 or 3 days later, with their maximum results about 30 days later. The effects will usually last about 4 months, and you can repeat the treatment at this time. You should not inject this botulinum toxin any more frequently than every 3 months.

Safety information

Botulinum toxins have established their safety after many millions of injections around the world. Some patients may experience minor side effects, and rarely, a patient may experience a rare allergic reaction, overdose, or the spread of toxic effect to another area of the body. If your patients experience symptoms such as difficulty breathing, difficulty swallowing, drooping eyelids, or hives, they should seek medical attention immediately because this could be life-threatening. The majority of patients may experience minor side effects at most, usually related to the injection itself and not specific to the solution injected. These side effects can include:

• Pain at injection site;

• Tenderness at injection site;

• Swelling;

• Bruising;

• Localized muscle weakness.

Recovery time after a treatment

These injections are minimally-invasive with no downtime. In fact, they are sometimes referred to as the lunchtime facelift because someone can have treatment and return to work immediately, with none the wiser. If the patient does experience side effects, they are usually minor, involving some pain, swelling, or bruising, but these usually resolve within a few days after treatment. Rarely, side effects can appear later and last longer. The majority of patients can immediately resume their normal activities after their injection.

Cost of Bocouture treatment

Doctors may charge different amounts for a treatment depending on their geographical location, but the cost to a patient may also vary by the amount of botulinum toxin needed, which depends on the size of the area treated, the condition of the patient’s skin and severity of their wrinkles, and other factors. The cost to the patient may be per unit, per vial, or per treatment area, but since the entire vial of reconstituted solution should be used within a certain time frame, many clinics will offer a limited-time sale or discount so patients book their appointments around the same time. In the U.S., injections usually cost between $240 to $415, or about $700 for a package. According to a study, Xeomin was the most cost-effective treatment compared to Dysport and Botox, so although Xeomin and its cosmetic version Bocouture are less well-known to the patient, many opt to save money with this more affordable option.

How does this botulinum toxin differ from Xeomin, Botox, and Dysport?

Bocouture and Xeomin are both made by Merz, with Bocouture marketed for cosmetic uses and Xeomin for medical uses. Otherwise, they are the same product, with equivalent units of botulinum toxin type A. Both are similar to Botox and Dysport in that they contain botulinum toxin type A, with units that are not equivalent, although Merz claims there are fewer complexing proteins in their products, making them less likely to trigger antibodies. They claim this means the product is less likely to lose effectiveness with repeated injections.